Gene News and Research

Latest Gene News and Research

AHRF to present free symposium on dizziness and balance disorders

The American Hearing Research Foundation will present a free, day-long educational symposium on dizziness and balance disorders on Saturday, April 6 at the Hilton Suites Chicago/Oakbrook in Oakbrook, Illinois.

27 Feb 2013

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new targeted therapies to potentially treat this deadly cancer.

27 Feb 2013

Surgical site infections appear to have significant genetic connections

An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame it partly on their genes.

27 Feb 2013

Research roundup: Patients hesitant to focus on costs; Increase in primary care demand is uneven

One way to contain health care spending is to get patients involved in weighing costs of treatment options with their doctors. Researchers recruited 211 medically insured participants to assess their willingness to consider costs when choosing treatments. The authors found that participants generally "preferred better care, even when the relative benefit it offered was marginal, and even when told that the second-best choice still met the threshold of 'good enough' care from a clinician's perspective.

26 Feb 2013

Insight into cellular operations that give extraordinary staying power to S. mansoni

From the point of view of its ultimate (human) host, the parasitic flatworm Schistosoma mansoni has a gruesome way of life. It hatches in feces-tainted water, grows into a larva in the body of a snail and then burrows through human skin to take up residence in the veins. Once there, it grows into an adult, mates and, if it's female, starts laying eggs. It can remain in the body for decades.

26 Feb 2013

HDAC-mediated mechanisms play critical role in regulating lung repair and regeneration

Lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are on the rise, according to the American Lung Association and the National Institutes of Health.

26 Feb 2013

Distinct bone marrow niches can nurture different types of blood stem cells

In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.

25 Feb 2013

Genetic testing strategy for familial high cholesterol questioned

Current testing strategies for the families of patients with familial hypercholesterolemia may not be an efficient use of health resources, suggest study results published in The Lancet.

25 Feb 2013

Individuals with psychogenic disease do have brains that function differently

Psychogenic diseases, formerly known as 'hysterical' illnesses, can have many severe symptoms such as painful cramps or paralysis but without any physical explanation. However, new research from the University of Cambridge and UCL (University College London) suggests that individuals with psychogenic disease, that is to say physical illness that stems from emotional or mental stresses, do have brains that function differently.

25 Feb 2013

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.

25 Feb 2013

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumour-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumour process, make the cancer tumour more sensitive to chemotherapy and to prevent the development of resistance.

25 Feb 2013

Study confirms presence of four molecular classes of head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of the disease has been established.

25 Feb 2013

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.

25 Feb 2013

Race and possibly genetics play a role in children's sensitivity to developing allergies

Research conducted at Henry Ford Hospital shows that race and possibly genetics play a role in children's sensitivity to developing allergies.

24 Feb 2013

HIF-1α protein can work directly to stop new cells from forming

A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying - known as DNA replication - and new cell growth to many of the body's functions and in such diseases as cancer.

23 Feb 2013

Leading cancer researcher, Dr. Lewis Cantley, named a winner of the inaugural Breakthrough Prize in Life Sciences

Dr. Lewis Cantley, a leading cancer researcher credited with discovering a family of enzymes fundamental to understanding cancer, was named a winner of the inaugural Breakthrough Prize in Life Sciences, the world’s richest academic prize for medicine and biology. The prize, which carries a $3 million cash award, recognizes excellence in research aimed at curing intractable diseases and human life.

22 Feb 2013

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Research published Online First in The Lancet provides new evidence that a substantial proportion of individuals with a clinical diagnosis of Familial Hypercholesterolaemia (FH) inherit a combination of small-effect changes in several genes (polygenic) rather than a large-effect mutation in a single gene (monogenic).

22 Feb 2013

Florida Hospital Pepin Heart Institute, USF partner for novel gene therapy trial

Cardiovascular disease specialists at Florida Hospital Pepin Heart Institute and Dr. Kiran C. Patel Research Institute affiliated with the University of South Florida announced they have enrolled their first patients into a clinical trial testing a novel gene therapy for the treatment of heart failure after ischemic injury. The therapy may promote the regeneration of heart tissue by encouraging the body to deploy more stem cells to the injury site.

22 Feb 2013

Combined complement mutations affect individuals' risk of aHUS and prognosis

Certain gene mutations affect individuals' risk of developing a serious kidney condition, as well as their prognosis after being diagnosed with the disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

22 Feb 2013

IntegraGen, Lab21 collaborate to develop new microRNA assay for colorectal cancer

Lab21 Limited, the global specialist in personalised medicine and clinical diagnostics, has entered into an agreement with IntegraGen, a leading player in the development and marketing of molecular diagnostic testing in autism and oncology, to develop a microRNA assay for colorectal cancer designed to further improve patient outcomes.

22 Feb 2013

Gene News and Research

Latest Gene News and Research

AHRF to present free symposium on dizziness and balance disorders

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Surgical site infections appear to have significant genetic connections

Research roundup: Patients hesitant to focus on costs; Increase in primary care demand is uneven

Insight into cellular operations that give extraordinary staying power to S. mansoni

HDAC-mediated mechanisms play critical role in regulating lung repair and regeneration

Distinct bone marrow niches can nurture different types of blood stem cells

Genetic testing strategy for familial high cholesterol questioned

Individuals with psychogenic disease do have brains that function differently

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

Study confirms presence of four molecular classes of head and neck squamous cell carcinoma

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Race and possibly genetics play a role in children's sensitivity to developing allergies

HIF-1α protein can work directly to stop new cells from forming

Leading cancer researcher, Dr. Lewis Cantley, named a winner of the inaugural Breakthrough Prize in Life Sciences

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Florida Hospital Pepin Heart Institute, USF partner for novel gene therapy trial

Combined complement mutations affect individuals' risk of aHUS and prognosis

IntegraGen, Lab21 collaborate to develop new microRNA assay for colorectal cancer

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