Gene News and Research

Latest Gene News and Research

Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

A Cedars-Sinai physician-scientist has been awarded a $3 million grant from the California Institute for Regenerative Medicine to study with new stem cell technology Charcot-Marie-Tooth disease, the most common inherited neurological disorder and which damages nerves that control muscles.

14 Dec 2012

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

Every time a human or bacterial cell divides it first must copy its DNA. Specialized proteins unzip the intertwined DNA strands while others follow and build new strands, using the originals as templates. Whenever these proteins encounter a break - and there are many - they stop and retreat, allowing a new cast of molecular players to enter the scene.

14 Dec 2012

National Cheng Kung University kicks off 23rd International Conference on Genome Informatics

National Cheng Kung University kicked off GIW 2012 -- the 23rd International Conference on Genome Informatics -- at International Conference Hall Dec. 12, attracting more than 140 scholars from 10 countries including Japan, Korea, China, Singapore, Canada, America, Germany, and Australia.

14 Dec 2012

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour - not only genes - drive tumour growth, contributing to therapy failure and relapse.

14 Dec 2012

Administration of N2O + ISO appears to have negative effect on fetal development

An anesthetic regimen typically used during surgery on pregnant mothers appears to have a negative effect on the development of the fetus, according to a new study on mice conducted by neurobiologists from the National Center for Toxicological Research, in Arizona.

14 Dec 2012

Knocking out PKNP gene is the Achilles' heel of some cancers

Medical researchers at the University of Alberta have discovered that knocking out a particular "partner" gene is the Achilles' heel of some cancers.

14 Dec 2012

Cedars-Sinai scientist to study Charcot-Marie-Tooth disease

14 Dec 2012

TUBB5 gene responsible for microcephaly: IMP study

Neurobiologists at the Research institute of Molecular Pathology (IMP) in Vienna have discovered one of the key genes required to make a brain. Mutations in this gene, called TUBB5, cause neurodevelopmental disease in children.

14 Dec 2012

Pairing statins with cyclin-dependent kinase inhibitors might effectively treat melanomas

A novel approach to identifying potential anticancer drug combinations revealed that pairing cholesterol-reducing drugs called statins with cyclin-dependent kinase inhibitors might provide an effective approach to treating intractable melanomas driven by mutations in the NRAS and KRAS gene.

14 Dec 2012

Meridian completes beta trials for two new illumigene molecular amplification tests

Meridian Bioscience, Inc. today announced that it has successfully completed beta trials for two new illumigene molecular amplification tests.

14 Dec 2012

MicroRNA-218 especially low in medulloblastoma

Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes or shrink the expression of helpful genes that would otherwise suppress tumors. A University of Colorado Cancer Center study published in the December issue of the Journal of Biological Chemistry shows that in medulloblastoma, a malignant brain tumor of children, microRNA-218 is especially low.

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

A computer model of the heart wall predicted risk of irregular heart rhythms and sudden cardiac death in patients, paving the way for the use of more complex cardiac models to calculate the consequences of genetic, lifestyle and other changes to the heart.

14 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

UCL scientists discover more than 200 gene locations for Crohn's disease

More than two hundred gene locations have now been identified for the chronic bowel condition Crohn's Disease, in a study that analysed the entire human genome.

13 Dec 2012

New way to effectively make designer drugs that hit collections of protein targets simultaneously

An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.

13 Dec 2012

GM604 target regulates over 4,000 genes: Genervon

Genervon scientists have confirmed that the target of GM604 regulates over 4,000 genes. More significantly, it modifies ALS disease progression by modulating at least 30 significant ALS related genes. It does this through at least 8 pathways, potentially more, and up to 22 biological processes.

13 Dec 2012

TSEC strategy can benefit postmenopausal women

Investigators at Wake Forest Baptist Medical Center have concluded research on a new postmenopausal hormone therapy that shows promise as an effective treatment for menopausal symptoms and the prevention of osteoporosis without increasing the risk for heart disease or breast cancer.

13 Dec 2012

Study focuses on nontraditional lifestyle of Retinoblastoma tumor suppressor proteins

Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.

13 Dec 2012

Study investigates different approaches to eradicate mosquito-borne diseases

A special issue of Pathogens and Global Health, published by Maney Publishing, investigates different approaches to eradicate mosquito-borne diseases. Mosquitoes can transmit a number of pathogenic diseases including dengue fever, yellow fever, and malaria.

13 Dec 2012

Gene News and Research

Latest Gene News and Research

Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

National Cheng Kung University kicks off 23rd International Conference on Genome Informatics

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Administration of N2O + ISO appears to have negative effect on fetal development

Knocking out PKNP gene is the Achilles' heel of some cancers

Cedars-Sinai scientist to study Charcot-Marie-Tooth disease

TUBB5 gene responsible for microcephaly: IMP study

Pairing statins with cyclin-dependent kinase inhibitors might effectively treat melanomas

Meridian completes beta trials for two new illumigene molecular amplification tests

MicroRNA-218 especially low in medulloblastoma

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

UCL scientists discover more than 200 gene locations for Crohn's disease

New way to effectively make designer drugs that hit collections of protein targets simultaneously

GM604 target regulates over 4,000 genes: Genervon

TSEC strategy can benefit postmenopausal women

Study focuses on nontraditional lifestyle of Retinoblastoma tumor suppressor proteins

Study investigates different approaches to eradicate mosquito-borne diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices