Gene News and Research

Latest Gene News and Research

Research explores molecular mechanisms connecting TBI to Alzheimer's

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer's disease later in life.

15 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

DNA changes from high potency cannabis use may signal psychosis risk

Published in Molecular Psychiatry, this is the first study to suggest that the use of high potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use.

15 Oct 2024

Genetic insights transform treatment for children with developmental disorders

Thousands of children with severe developmental disorders have benefited from more targeted treatments and support with genetic insights from the large-scale Deciphering Developmental Disorders (DDD) study, finds a new study.

15 Oct 2024

Genetics identified as key factor in gout development

A major international study has found gout is a chronic illness where genetics is a major cause, rather than lifestyle choices of the sufferer.

15 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Scripps Research identifies binding site on challenging cancer protein

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate.

15 Oct 2024

Breakthrough in understanding microtubule formation in cells

Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another.

15 Oct 2024

Mayo Clinic scientists develop mini brain models to study Lewy body dementia

Lewy body dementia (LBD) is a progressive neurodegenerative disease that shares traits with both Parkinson's disease and Alzheimer's disease but can be more difficult to diagnose.

15 Oct 2024

New gene therapy offers hope in combatting childhood obesity

According to the Centers for Disease Control, nearly 20% of children and teens are considered obese.

14 Oct 2024

Uncovering human-specific genes linked to brain development and disorders

The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities.

14 Oct 2024

Exploring the role of CPB2 gene in C. perfringens infections

C. perfringens is a widespread bacterium found in the intestines of animals and humans, known for causing severe enteric diseases.

14 Oct 2024

Differential gene expression linked to alcohol use disorder, offering new treatment possibilities

Researchers identified key gene expression differences in addiction-relevant brain regions that provide new insights into alcohol use disorder and potential therapeutic targets.

14 Oct 2024

Epigenomic dynamics shape human brain development and neuropsychiatric disorder risks

Researchers investigate chromatin conformational and epigenomic reorganization during the development of the prefrontal cortex and hippocampus.

14 Oct 2024

Discovery of USP50 protein sheds light on DNA replication processes

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study.

14 Oct 2024

Calluna Pharma appoints Mark Gaffney as Chief Executive Officer and Mark Altmeyer as Independent Chair of the Board

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the appointments of Mark Gaffney as Chief Executive Officer and Mark Altmeyer as Chair of the Board.

From Calluna Pharma 14 Oct 2024

Clec14a protein found to play vital role in regulating bone formation and density

The role of the C-type lectin domain containing 14A (Clec14a), a type-H endothelial protein, in coordinating osteoblast activity.

14 Oct 2024

Motor delays and hypotonia differentiate neurodevelopmental disease patients with and without genetic diagnoses

Researchers identified key clinical factors like motor delays and hypotonia that predict genetic diagnoses in children with neurodevelopmental disorders, creating a decision tree to guide clinicians.

14 Oct 2024

A novel approach to understanding protein compartmentalization

In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of high- and low-density phases in supercooled water and the coexistence of metal puddles in an insulating matrix in the Mott metal-insulator transition.

14 Oct 2024

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024