Gene News and Research

Latest Gene News and Research

Researchers create online database of disease genes that could be targeted with drugs

Researchers at Washington University School of Medicine in St. Louis have created a massive online database that matches thousands of genes linked to cancer and other diseases with drugs that target those genes.

14 Oct 2013

Patient with certain gene variation more likely to suffer cognitive decline five years after surgery

Long-term memory loss, difficulty understanding verbal or written communication or impaired ability to pay attention may still occur five years after heart surgery if a patient has a certain gene variation, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Scientists discover genetic mutation associated with low-risk bladder cancer

An international research team led by scientists from Georgetown Lombardi Comprehensive Cancer Center has discovered a genetic mutation linked to low-risk bladder cancer.

13 Oct 2013

New approach could help identify specific gene mutations linked to increased disease risk

Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.

13 Oct 2013

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Conventional chemotherapy could further extend life in some women with ovarian cancer when used in tandem with a new type of targeted treatment, a new international study shows.

13 Oct 2013

Study evaluates possibility of individualisation of castration-resistant prostate cancer management

A new study reveals that in the prediction of treatment outcome for castration-resistant prostate cancer, a change in circulating tumour cells detection might be more accurate than the change in prostate-specific antigen levels. The findings of this award-winning study were presented at the recent EAU 13th Central European Meeting in Prague.

12 Oct 2013

Research findings may lead to new ways to combat cancer

The way cells divide to form new cells - to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning - is controlled in previously unsuspected ways UC San Francisco researchers have discovered.

12 Oct 2013

Change in gene expression occurs in patients with "pouchitis" after UC surgery

"Pouchitis" developing after surgery for ulcerative colitis (UC) is associated with changes in gene expression, which increase along with disease severity, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

11 Oct 2013

New gene transfer strategy effective for achieving persistent immunotherapy to treat tumors

Cancer immunotherapy can successfully use the body's own immune system to kill tumor cells. But some current approaches to stimulate an antitumor immune response are short-lived, with limited clinical effectiveness. A new gene transfer strategy that introduces modified, immune-stimulating human stem cells is both feasible and effective for achieving persistent immunotherapy to treat leukemias and lymophomas, according to a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

11 Oct 2013

HSCI researchers discover on-off switch for gene expression

Harvard Stem Cell Institute researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before they are methylated.

11 Oct 2013

Super-enhancers could play important roles in disease diagnostics and therapeutics

Having recently discovered a set of powerful gene regulators that control cell identity in a few mouse and human cell types, Whitehead Institute scientists are now showing that these regulators-which they named "super-enhancers"-act across a vast array of human cell types and are enriched in mutated regions of the genome that are closely associated with a broad spectrum of diseases.

11 Oct 2013

TSRI scientists discover viable strategy for weight loss in people

Scientists at The Scripps Research Institute have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from the worm versions of the neurotransmitters serotonin and adrenaline, and there are reasons to suspect that it exists in a similar form in humans and other mammals.

11 Oct 2013

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

A Ludwig Cancer Research study published in Cell today identifies a common mutation that dramatically increases the risk for testicular cancer—and describes a likely molecular mechanism by which it exerts that effect.

11 Oct 2013

Cedars-Sinai woman researcher puts extensive effort to increase awareness on ovarian cancer research

Julie Miller is a key part of an extensive effort at Cedars-Sinai to increase awareness of and support for women's cancer research. She not only has registered to participate in clinical research, but she's also lacing up her running shoes.

11 Oct 2013

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

The National University of Singapore (NUS) and A*STAR will be jointly establishing the S$148 million Singapore Centre for Nutritional Sciences, Metabolic Diseases, and Human Development (SiNMeD).

11 Oct 2013

FDA accepts, files Genentech's sBLA for subcutaneous use of Xolair in people with CIU

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted and filed the company's supplemental Biologics License Application for subcutaneous use of Xolair (omalizumab) in people with Chronic Idiopathic Urticaria who remained symptomatic despite treatment with H1-antihistamine therapy at approved doses.

11 Oct 2013

Researchers find ways to identify, isolate HCC progenitor cells before tumors become evident

For the first time, researchers at the University of California, San Diego School of Medicine have isolated and characterized the progenitor cells that eventually give rise to malignant hepatocellular carcinoma tumors - the most common form of liver cancer. The researchers found ways to identify and isolate the HCC progenitor cells long before actual tumors were apparent.

11 Oct 2013

Researchers identify gene that orchestrates important branching of nerve fibers

Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.

11 Oct 2013

Small interfering RNAs in mammals act as specific antiviral weapons

Many viral infections are nipped in the bud by the innate immune response. This involves specific proteins within the infected cell that recognize the virus and trigger a signalling cascade - the so-called interferon response. This activates a protective mechanism in neighbouring cells and often results in the death of the primarily infected cell.

11 Oct 2013

Genetic variation can affect how people see and experience the world

A new study by a University of British Columbia researcher finds that some people are genetically predisposed to see the world darkly.

11 Oct 2013

Gene News and Research

Latest Gene News and Research

Researchers create online database of disease genes that could be targeted with drugs

Patient with certain gene variation more likely to suffer cognitive decline five years after surgery

Scientists discover genetic mutation associated with low-risk bladder cancer

New approach could help identify specific gene mutations linked to increased disease risk

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Study evaluates possibility of individualisation of castration-resistant prostate cancer management

Research findings may lead to new ways to combat cancer

Change in gene expression occurs in patients with "pouchitis" after UC surgery

New gene transfer strategy effective for achieving persistent immunotherapy to treat tumors

HSCI researchers discover on-off switch for gene expression

Super-enhancers could play important roles in disease diagnostics and therapeutics

TSRI scientists discover viable strategy for weight loss in people

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

Cedars-Sinai woman researcher puts extensive effort to increase awareness on ovarian cancer research

NUS, A*STAR establish joint center to study role of nutrition and development in health, disease in Asia

FDA accepts, files Genentech's sBLA for subcutaneous use of Xolair in people with CIU

Researchers find ways to identify, isolate HCC progenitor cells before tumors become evident

Researchers identify gene that orchestrates important branching of nerve fibers

Small interfering RNAs in mammals act as specific antiviral weapons

Genetic variation can affect how people see and experience the world

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research