Gene News and Research

Latest Gene News and Research

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

New Studies in Mice Support Toxic Role of Aluminum in Neurodegenerative Conditions, According to Report in Restorative Neurology and Neuroscience

3 Aug 2013

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Specific mutations in FLT3 receptor can contribute to acute myeloid leukemia

Specific mutations (N676K) in the FLT3 receptor can contribute to the development of acute myeloid leukemia. The FLT3 receptor regulates cell growth, while activating gene mutations promote the uncontrolled proliferation of white blood cells. These findings were reported in the specialist journal Blood by a group of scientists from the Helmholtz Zentrum München and the Hospital of the Ludwig Maximilians University in Munich as part of a clinical research collaboration with the German Cancer Consortium.

3 Aug 2013

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

Castle Biosciences Inc. announced that data from studies of its DecisionDx-Melanoma test are being presented today at the Summer Academy Meeting of the American Academy of Dermatology. The validation data confirm previous studies showing that the gene expression profile test is a strong independent predictor for classifying which Stage I or II non-metastatic cutaneous melanoma patients will likely recur.

2 Aug 2013

Keeping Alzheimer's disease in check

The future is looking good for drugs designed to combat Alzheimer's disease. EPFL scientists have unveiled how two classes of drug compounds currently in clinical trials work to fight the disease. Their research suggests that these compounds target the disease-causing peptides with high precision and with minimal side-effects.

2 Aug 2013

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

The American Society of Hematology will present the 2013 William Dameshek Prize to Andrew S. Weyrich, PhD, of The University of Utah for his seminal research on the cellular and molecular causes of blood clots.

2 Aug 2013

NanoString announces Early Access Program for nCounter Elements used in translational research

NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced an Early Access Program for nCounter Elements™, a line of General Purpose Reagents (GPRs) developed specifically to meet the needs of translational research and clinical laboratories.

From NanoString Technologies 2 Aug 2013

Protein linked to learning induces cocaine addiction, say researchers

A team of researchers says it has solved the longstanding puzzle of why a key protein linked to learning is also needed to become addicted to cocaine. Results of the study, published in the Aug. 1 issue of the journal Cell, describe how the learning-related protein works with other proteins to forge new pathways in the brain in response to a drug-induced rush of the “pleasure” molecule dopamine.

2 Aug 2013

Duke Medicine researchers identify a protein critical to TMJD pain

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments.

2 Aug 2013

New finding suggests potential to improve safety, performance of reprogrammed cells

The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

2 Aug 2013

Study offers new hope for treatment of diffuse large B-cell lymphoma

Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

2 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Scientists prevent cell sleep to reduce chance of tumor recurrence

An international research team led by University of Pittsburgh Cancer Institute (UPCI) scientists discovered that by preventing cancer cells from entering a state of cellular sleep, cancer drugs are more effective, and there is a lower chance of cancer recurrence.

2 Aug 2013

Researchers find a crucial on-off switch in visual development

A discovery by a University of Maryland-led research team offers hope for treating "lazy eye" and other serious visual problems that are usually permanent unless they are corrected in early childhood.

2 Aug 2013

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

If you think stress is killing you, you may be right, but what you don't know is that stress might have harmed your health even before you were born. In a new report appearing in the August 2013 issue of The FASEB Journal, Harvard researchers find that epigenetic disruptions, which are associated with chronic disease later in life, are already common at birth.

2 Aug 2013

Verinata Health receives New York's Laboratory Permit for CLIA-certified verifi prenatal test

Illumina, Inc. (NASDAQ: ILMN) today announced that Verinata Health, an Illumina company, received the Clinical Laboratory Permit from the New York State Department of Health for its CLIA-certified, CAP-accredited laboratory.

2 Aug 2013

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings are published today, Aug. 1, in the journal Skeletal Muscle.

2 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Bethesda, MD-Japanese researchers have made a new step toward understanding why-and how to stop-runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The FASEB Journal scientists show that two receptors of an inflammatory molecule, called "leukotriene B4," play opposing roles in turning inflammation on and off for allergic asthma and COPD.

2 Aug 2013

Researchers hope to exploit unique metabolic profile of cancer

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

2 Aug 2013

Gene News and Research

Latest Gene News and Research

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

Specific mutations in FLT3 receptor can contribute to acute myeloid leukemia

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

Keeping Alzheimer's disease in check

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

NanoString announces Early Access Program for nCounter Elements used in translational research

Protein linked to learning induces cocaine addiction, say researchers

Duke Medicine researchers identify a protein critical to TMJD pain

New finding suggests potential to improve safety, performance of reprogrammed cells

Study offers new hope for treatment of diffuse large B-cell lymphoma

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Scientists prevent cell sleep to reduce chance of tumor recurrence

Researchers find a crucial on-off switch in visual development

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

Verinata Health receives New York's Laboratory Permit for CLIA-certified verifi prenatal test

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

UCLA researchers develop treatment approach for breast cancer metastasized to brain

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Researchers hope to exploit unique metabolic profile of cancer

Genomics - Industry Focus eBook (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research