Gene News and Research

Latest Gene News and Research

ACCR designates Georgetown student as early-career scientist

David A. Solomon, who will graduate from Georgetown University School of Medicine this year with M.D. and Ph.D. degrees, has been designated one of four outstanding early-career scientists by the American Association for Cancer Research (AACR) -- a highly prestigious honor. Solomon will present his work at a special symposium, Future Leaders in Basic Cancer Research, on April 2nd at the AACR Annual Meeting 2012 in Chicago.

28 Mar 2012

Imatinib improves RFS, overall survival in GIST patients after surgery

Among patients with a high risk of recurrence of a gastrointestinal stromal tumor following surgery for its removal, patients who received imatinib (a drug to treat certain cancers) for 3 years instead of 1 had improved recurrence-free survival and overall survival, according to a study in the March 28 issue of JAMA.

28 Mar 2012

Study examines link between lab-tested drugs and defective protein that causes CF

Cystic fibrosis is the most common fatal genetic disease affecting Canadian children and young adults, more than two children each and every week are diagnosed with cystic fibrosis (CF). New research at Ryerson University, in partnership with The Hospital for Sick Children, is examining the interaction between lab-tested drugs and the defective protein that causes CF to understand how and why the drugs work and to create stronger, more powerful second generation drugs to treat CF.

28 Mar 2012

Direct Molecular Recognition technique can quantitate multiple DNA species

Researchers at UCLA and New York University have developed a method to detect sequence differences in individual DNA molecules by taking nanoscopic pictures of the molecules themselves.

28 Mar 2012

Researchers identify genetic causes in nearly 1 in 5 patients with dilated cardiomyopathy

Researchers have identified genetic causes in nearly 1 in 5 patients who suffer a type of heart failure called dilated cardiomyopathy.

28 Mar 2012

Simple genetic test could help predict aggressiveness of rhabdomyosarcoma tumours

A study led by Dr Janet Shipley from The Institute of Cancer Research (ICR) in London in collaboration with Dr Mauro Delorenzi from the SIB Swiss Institute of Bioinformatics in Lausanne has shown that a simple genetic test could help predict the aggressiveness of rhabdomyosarcoma tumours in children

28 Mar 2012

New gene transfer technique can treat beta-thalassemia, sickle cell anemia

A team of researchers led by scientists at Weill Cornell Medical College has designed what appears to be a powerful gene therapy strategy that can treat both beta-thalassemia disease and sickle cell anemia. They have also developed a test to predict patient response before treatment.

28 Mar 2012

Experimental drugs from Sanofi and Regenron cut cholesterol in a new way

An experimental drug that acts in a novel way to lower cholesterol proved even more effective than statins and had few undesirable side effects, newly released data shows. The drug acts by modifying the way cholesterol levels are naturally controlled. A protein produced in the liver helps limit the amount of LDL, or “bad” cholesterol, that liver cells can remove from the bloodstream. The new drug, called REGN727, is a monoclonal antibody, made in a laboratory, that blocks the action of that protein.

27 Mar 2012

Pfizer to present data on ADCs at AACR 2012

Pfizer Oncology will present data from a variety of preclinical and clinical studies of Pfizer's early-stage compounds, including data from Pfizer's investigational antibody-drug conjugate (ADC) portfolio and research evaluating several molecules targeting novel pathways that play a crucial role in basic cellular functions, at the American Association for Cancer Research (AACR) Annual Meeting 2012 in Chicago, IL, from March 31-April 4.

27 Mar 2012

IU biologist to genetically modify variants of chlamydia

An Indiana University biologist has been awarded over $2.3 million from the National Institutes of Health to genetically modify variants of the human pathogen chlamydia in hopes of finding a vaccine for the most commonly reported bacterial infectious disease in the United States.

27 Mar 2012

GE Healthcare, DiaGenic enter research collaboration to develop blood-based test for MCI

DiaGenic ASA today announced a research agreement to collaborate with GE Healthcare to develop a blood-based test using DiaGenic's peripheral gene expression profiling in patients with mild cognitive impairment, a disorder associated with risk for Alzheimer's Disease.

27 Mar 2012

Defects in schizophrenia-risk genes and environmental stress lead to abnormal brain development

Working with genetically engineered mice and the genomes of thousands of people with schizophrenia, researchers at Johns Hopkins say they now better understand how both nature and nurture can affect one's risks for schizophrenia and abnormal brain development in general.

27 Mar 2012

Study identifies major gene affecting chronic pain sensitivity

Nearly one in five people suffers from the insidious and often devastating problem of chronic pain.

27 Mar 2012

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

In the first published study of its kind, researchers from the Catholic University/Policlinico Gemelli in Rome, Italy, and NewYork-Presbyterian/Weill Cornell Medical Center found that bariatric surgery dramatically outperforms standard medical treatment of severe type 2 diabetes.

27 Mar 2012

ACS symposium focuses on biomimetics

Combining the secrets that enable water striders to walk on water and give wood its lightness and great strength has yielded an amazing new material so buoyant that, in everyday terms, a boat made from 1 pound of the substance could carry five kitchen refrigerators, about 1,000 pounds.

27 Mar 2012

Gene fault linked to flu risk for hospitalization: Study finds

Researchers have found a genetic flaw that may explain why some people get more ill with flu than others. The study was reported in the journal Nature this Sunday, where researchers said the variant of the IFITM3 gene was much more common in people hospitalized for flu than in the general population. It controls a malformed protein, which makes cells more susceptible to viral infection. Experts said those with the flaw could be given the flu jab, like other at-risk groups.

26 Mar 2012

USPTO issues patent to Inovio's SynCon H1N1 influenza vaccine

Inovio Pharmaceuticals, Inc. announced today that the United States Patent and Trademark Office granted U.S. Patent No. 8,133,723, covering Inovio's SynCon universal vaccine related to H1N1 influenza.

26 Mar 2012

Hi-tech 3D imaging may improve lives of chronic lung disease patients

Pioneering research in Southampton, using hi-tech 3D imaging, could improve the lives of those suffering from chronic lung disease.

26 Mar 2012

Mutational profiling could determine which AML patients will benefit from dose-intensive chemotherapy

An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that analyzed mutations in 18 genes of 398 patients who had acute myeloid leukemia.

26 Mar 2012

Study reveals central role played by DBIRD protein complex in gene transcription

In a study published this week in the journal Nature, researchers at the University of Liège's GIGA Unit, together with English and German teams, reveal the central role played by a protein complex, unknown up to now, in gene transcription.

26 Mar 2012

Gene News and Research

Latest Gene News and Research

ACCR designates Georgetown student as early-career scientist

Imatinib improves RFS, overall survival in GIST patients after surgery

Study examines link between lab-tested drugs and defective protein that causes CF

Direct Molecular Recognition technique can quantitate multiple DNA species

Researchers identify genetic causes in nearly 1 in 5 patients with dilated cardiomyopathy

Simple genetic test could help predict aggressiveness of rhabdomyosarcoma tumours

New gene transfer technique can treat beta-thalassemia, sickle cell anemia

Experimental drugs from Sanofi and Regenron cut cholesterol in a new way

Pfizer to present data on ADCs at AACR 2012

IU biologist to genetically modify variants of chlamydia

GE Healthcare, DiaGenic enter research collaboration to develop blood-based test for MCI

Defects in schizophrenia-risk genes and environmental stress lead to abnormal brain development

Study identifies major gene affecting chronic pain sensitivity

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

ACS symposium focuses on biomimetics

Gene fault linked to flu risk for hospitalization: Study finds

USPTO issues patent to Inovio's SynCon H1N1 influenza vaccine

Hi-tech 3D imaging may improve lives of chronic lung disease patients

Mutational profiling could determine which AML patients will benefit from dose-intensive chemotherapy

Study reveals central role played by DBIRD protein complex in gene transcription

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