Gene News and Research

Latest Gene News and Research

Researchers discover biological mechanism behind sarcopenia

Researchers at Columbia University Medical Center have discovered the biological mechanism behind age-related loss of muscle strength and identified a drug that may help reverse this process.

3 Aug 2011

Illumina board authorizes new $100 million share repurchase program

Illumina today announced that on August 1, 2011, its Board of Directors authorized the Company to repurchase, on a discretionary basis, up to $100 million of its outstanding common shares in the open market or in privately negotiated transactions, subject to market conditions and other factors. The previous discretionary $100 million share repurchase program authorized in July 2010 was completed this week.

From Illumina, Inc. 3 Aug 2011

Chromogenic in situ hybridization can identify ALK rearrangement in lung cancer patients

A relatively simple and inexpensive method may be used to determine whether a lung cancer patient is a candidate for crizotinib therapy, according to research published in the August issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer.

3 Aug 2011

Combination molecules with BRAF inhibitors may help overcome drug resistance in melanoma patients

About 50 to 60 percent of patients with melanoma have a mutation in the BRAF gene that drives the growth of their cancer. Most of these patients respond well to two novel agents being studied in clinical trials that inhibit the gene, with remarkable responses that are, unfortunately, almost always limited in duration.

3 Aug 2011

Insight into how brain organizes during development

Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. The findings, published in the Journal of Comparative Neurology today, describe - in more detail than ever before - the consequences of the loss of a key molecule involved in establishing proper brain architecture during brain development.

3 Aug 2011

Positive results from combination drug trial for late-stage ovarian cancer

An experimental two-drug combination for treating late-stage ovarian cancer continues to produce strong results, leading its Indiana University researchers to actively pursue the next step, conducting a larger clinical trial to test the therapy and to see how it compares with existing treatments for ovarian cancer.

3 Aug 2011

VIB researchers develop mouse model for Charcot-Marie-Tooth neuropathy

VIB researchers have developed a mouse model for Charcot-Marie-Tooth (CMT) neuropathy, a hereditary disease of the peripheral nervous system.

3 Aug 2011

Nottingham animal scientist receives 'Marshall Medal' for fertility and reproduction study

A leading University of Nottingham animal scientist has been awarded one of the most prestigious medals in the field of animal reproductive biology.

3 Aug 2011

Lifestyle factors of people with exceptional longevity

People who live to 95 or older are no more virtuous than the rest of us in terms of their diet, exercise routine or smoking and drinking habits, according to researchers at Albert Einstein College of Medicine of Yeshiva University.

3 Aug 2011

Federal appeals court partially reverses ruling in BRCA patents case

In a 2-1 decision, a federal appeals court today partially reversed a lower court's ruling in a case challenging patents on two human genes, BRCA1 and BRCA2, associated with hereditary breast and ovarian cancer. The court ruled that companies can obtain patents on the genes but cannot patent methods to compare those gene sequences.

3 Aug 2011

Vanderbilt researcher receives Waxman Foundation's award for B-cell lymphoma study

Scott Hiebert, Ph.D., of Vanderbilt University was awarded a $25,000 grant from the Samuel Waxman Cancer Research Foundation to further his research in abnormal BCL6 overexpression, which occurs in a common B-cell lymphoma.

3 Aug 2011

New insights into genesis and development of Sézary syndrome

Scientists at Charité - Universitätsmedizin Berlin, Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, the Max-Planck-Institut für Molekulare Genetik Berlin, and four other German institutes succeeded in proving a specific gene loss in a certain human lymphoma, the genesis of which is largely unexplained to date.

3 Aug 2011

British scientists find seven new gene variants linked to prostate cancer

Cancer Research UK-funded scientists have taken a further step to identifying men at a greater risk of prostate cancer with the discovery of seven new variants in the human genome that increase the chances of developing the disease. The research is published in Nature Genetics.

3 Aug 2011

GSK, NPS enter agreement to evaluate ronacaleret in new indications

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing orphan therapeutics for rare gastrointestinal and endocrine disorders, today reported that it has entered into a new agreement with GlaxoSmithKline (GSK), that terminates and replaces a prior collaborative research and license agreement between NPS and GSK from 1993, which focused on the discovery and development of small molecule antagonists of the calcium receptor that increase secretion of parathyroid hormone.

3 Aug 2011

Lipid nanocarriers in cancer diagnosis and therapy: New book

This book introduces fundamental principles of lipid nanocarriers science relevant to cancer therapy. The first in this field, it fills a need for an accurate, coherent and authoritative introduction to lipid nanocarriers focusing in cancer therapy; both because of the growing popularity of these modern drug delivery systems and also because of the emergent need of dealing with cancer treatment.

2 Aug 2011

Scientists look to create blood platelets from stem cells to study genetics of blood clotting disorders

Johns Hopkins scientists have launched a pioneering research program to create, for the first time, human platelet cells from stem cells in order to study inherited blood clotting abnormalities ranging from clots that cause heart attacks and stroke to bleeding disorders. The study is funded by a $9 million grant from the National Institutes of Health (NIH) as part of a nationwide initiative to examine how genetic variations cause heart, lung and blood diseases.

2 Aug 2011

Lack of TLR1 surface expression linked with increased susceptibility to tuberculosis

Are you genetically predisposed to tuberculosis? Scientists may now be able to answer this question and doctors may be able to adjust their therapeutic approach based on what they learn. That's because new research presented in the Journal of Leukocyte Biology suggests that two frequent mutations in an immune system gene called TLR1 are responsible for cellular changes that ultimately make us less likely to resist the disease.

2 Aug 2011

Positive results from Jennerex JX-594 proof-of-concept trial on metastatic melanoma

Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic products for cancer, today announced that positive results from a proof-of-concept clinical trial using JX-594 to treat patients with metastatic melanoma were published in the peer-reviewed journal Molecular Therapy.

2 Aug 2011

Elsevier launches new interactive feature for life sciences journals

Elsevier, a world-leading provider of scientific, technical and medical information products and services, introduces the Genome Viewer, a new interactive feature on SciVerse ScienceDirect for applicable life sciences journals.

2 Aug 2011

Alnylam second quarter revenue decreases to $20.6 million

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today reported its consolidated financial results for the second quarter 2011, and company highlights.

From Precision NanoSystems Inc. 2 Aug 2011

Gene News and Research

Latest Gene News and Research

Researchers discover biological mechanism behind sarcopenia

Illumina board authorizes new $100 million share repurchase program

Chromogenic in situ hybridization can identify ALK rearrangement in lung cancer patients

Combination molecules with BRAF inhibitors may help overcome drug resistance in melanoma patients

Insight into how brain organizes during development

Positive results from combination drug trial for late-stage ovarian cancer

VIB researchers develop mouse model for Charcot-Marie-Tooth neuropathy

Nottingham animal scientist receives 'Marshall Medal' for fertility and reproduction study

Lifestyle factors of people with exceptional longevity

Federal appeals court partially reverses ruling in BRCA patents case

Vanderbilt researcher receives Waxman Foundation's award for B-cell lymphoma study

New insights into genesis and development of Sézary syndrome

British scientists find seven new gene variants linked to prostate cancer

GSK, NPS enter agreement to evaluate ronacaleret in new indications

Lipid nanocarriers in cancer diagnosis and therapy: New book

Scientists look to create blood platelets from stem cells to study genetics of blood clotting disorders

Lack of TLR1 surface expression linked with increased susceptibility to tuberculosis

Positive results from Jennerex JX-594 proof-of-concept trial on metastatic melanoma

Elsevier launches new interactive feature for life sciences journals

Alnylam second quarter revenue decreases to $20.6 million

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development