Gene News and Research

Latest Gene News and Research

NIAID awards $36M grant to BIDMC for AIDS vaccine research in nonhuman primates

Beth Israel Deaconess Medical Center (BIDMC) has been awarded a grant from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to lead a Consortium for AIDS Vaccine Research in Nonhuman Primates.

21 Jul 2011

Cell biologists identify infection mechanism of adenoviruses

Mucosal epithelia do not have any receptors on the outer membrane for the absorption of viruses like hepatitis C, herpes, the adenovirus or polio, and are thus well-protected against pathogenic germs. However, certain viruses, such as the human immunodeficiency virus HIV, still manage to enter the body via the mucous membrane.

21 Jul 2011

Children and adults with social withdrawal due to Fragile X may benefit from STX209

Children and adults with social withdrawal due to Fragile X syndrome, the most common cause of inherited intellectual disability and the most common known single gene cause of autism, may benefit from an experimental drug under study by pediatric neurologists at Rush Children's Hospital at Rush University Medical Center.

21 Jul 2011

Researchers develop mouse model of rare human birth defect

A team of researchers from the University of Utah and Brigham Young University has developed a mouse model of focal dermal hypoplasia, a rare human birth defect that causes serious skin abnormalities and other medical problems. This animal model not only provides insight into studying the cause of focal dermal hypoplasia (FDH), but also offers a novel way to study a signaling pathway that is crucial for embryonic development.

21 Jul 2011

Lonza, Cellectis reach milestone in development of newly bioengineered cell line

Cellectis bioresearch, the genome customization specialist and a commercial subsidiary of Cellectis, and Lonza, a world leader in biotechnology production, announce today that they have reached a significant milestone in the development of a newly bioengineered cell line.

21 Jul 2011

Genetically engineered excitable cells made to generate and pass electrical current

By altering the genetic makeup of normally "unexcitable" cells, Duke University bioengineers have turned them into cells capable of generating and passing electrical current.

21 Jul 2011

Localized one-time gene therapy might effectively protect against atherosclerosis

A one-dose method for delivering gene therapy into an arterial wall effectively protects the artery from developing atherosclerosis despite ongoing high blood cholesterol.

21 Jul 2011

Loss of critical male development gene causes male cells to become female

University of Minnesota Medical School and College of Biological Sciences researchers have made a key discovery showing that male sex must be maintained throughout life.

21 Jul 2011

Computer modeling to predict how peripheral nerve axon responds to electrical stimuli

Researchers at Case Western Reserve University have developed a computer modeling method to accurately predict how a peripheral nerve axon responds to electrical stimuli, slashing the complex work from an inhibitory weeks-long process to just a few seconds.

21 Jul 2011

Humans and zebrafish share mechanisms that regulate the circadian system

Circadian rhythms - the natural cycle that dictates our biological processes over a 24-hour day - does more than tell us when to sleep or wake. Disruptions in the cycle are also associated with depression, problems with weight control, jet lag and more. Now Prof. Yoav Gothilf of Tel Aviv University's Department of Neurobiology at the George S. Wise Faculty of Life Sciences is looking to the common zebrafish to learn more about how the human circadian system functions.

21 Jul 2011

Gene-based test for distinguishing harmless from precancerous pancreatic cysts

Johns Hopkins scientists have developed a gene-based test to distinguish harmless from precancerous pancreatic cysts. The test may eventually help some patients avoid needless surgery to remove the harmless variety.

21 Jul 2011

Promising results from phase I study of Genentech's GDC-0941 for advanced breast cancer

A new drug targeting the PI3K gene in patients with advanced breast cancer shows promising results in an early phase I investigational study conducted at Virginia G. Piper Cancer at Scottsdale Healthcare, according to a presentation by oncologist Dr. Daniel D. Von Hoff at the 47th annual meeting of the American Society of Clinical Oncology.

21 Jul 2011

USPTO issues patent for Mirna's tumor suppressor microRNAs

Mirna Therapeutics, Inc. announced today that the United States Patent and Trademark Office has allowed multiple patent claims related to the therapeutic application of several tumor suppressor microRNAs.

21 Jul 2011

Adamis' APC-300 inhibits growth of prostate cancer cells

Adamis Pharmaceuticals Corporation announced today that in addition to activity in pancreatic cancer and its multiple modes of action, APC-300 significantly inhibits the growth of prostate cancer cells.

21 Jul 2011

Babies of stressed pregnant mums may have lasting effects

According to a new study high levels of stress during pregnancy can cause an unborn child to have lifelong mental scars. Researchers have found that a mother facing unnecessary crises can leave an imprint in the brains of her children, making them less able to cope as they get older.

20 Jul 2011

Male infertility cause found in defective gene

Researchers have found a new cause of infertility that could allow millions of infertile couples around the world to have a child. The team found a common gene mutation that causes sperm to be far less able to swim through the mucus of the cervix and reach the egg.

20 Jul 2011

Diabetes gene linked to Alzheimer’s

Researchers from Mount Sinai School of Medicine have identified a gene that causes diabetes kills nerve cells in the brain, possibly resulting in Alzheimer’s disease.

20 Jul 2011

New insights into sleep difficulties among older people

A new study of the brain's master circadian clock - known as the suprachiasmatic nucleus, or SCN - reveals that a key pattern of rhythmic neural activity begins to decline by middle age. The study, whose senior author is UCLA Chancellor Gene Block, may have implications for the large number of older people who have difficulty sleeping and adjusting to time changes.

20 Jul 2011

Scientists discover new dominant gene linked to Parkinson's

The newly discovered gene is known as VPS35, the sixth one which has been associated with Parkinson's disease and the third dominant gene.

20 Jul 2011

New transgenic mouse could predict toxicity of targeted cancer drugs

Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product. The majority of new agents are only shown to be unsuitable in the later phases of clinical development which would explain the exorbitantly high development costs of 500 to 600 million euros per new cancer drug.

20 Jul 2011