Gene News and Research

Latest Gene News and Research

Overexpression of microRNA 125b can cause leukemia: Research

Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease's progression. Their results are published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS).

30 Nov 2010

Ageing reversed in mice: Study

A scientific team at Harvard-affiliated medical centers genetically manipulated mice to age faster. Then they used gene therapy to lengthen telomeres. Telomeres are compounds found at the ends of strands of DNA that are related to age. This lengthening of telomeres reversed age-related problems such as decreased brain function and infertility.

29 Nov 2010

Hemispherx requests FDA time extension for Ampligen NDA data resubmission

Hemispherx Biopharma, Inc., announced that the Company has requested an extension of time in which to resubmit data to its NDA for Ampligen®, an experimental therapeutic, to treat CFS.

29 Nov 2010

Depressed and suicidal individuals linked to low levels of stress hormone cortisol

Depressed and suicidal individuals have low levels of the stress hormone cortisol in their blood and saliva. They also have substances in their spinal fluid that suggest there is increased inflammation in the brain. These findings could help to develop new methods for diagnosing and treating suicidal patients.

29 Nov 2010

QIAGEN to supply point-of-need molecular veterinary diagnostics for disease detection in emerging countries

QIAGEN has been selected to contribute to the fight against infectious diseases in animals in emerging countries by supplying an international pilot project associated with the United Nations with portable devices to perform ultra-fast molecular testing in the field.

From QIAGEN Manchester Limited 29 Nov 2010

Marcus evans Summit highlights potential growth, innovation in drug discovery

Drug discovery scientists need to broaden their approaches to pharmaceutical research and development (R&D) and Medicinal Chemistry, to take advantage of untapped opportunities, says Torsten Hoffmann, Head Discovery Chemistry at F. Hoffmann La Roche, Basel, Switzerland. Chemical Biology allows room for innovation, but is often overlooked by scientists in the industry.

29 Nov 2010

Study finds association between DGKK gene and hypospadias

Hypospadias is a common congenital malformation of the male external genitalia, affecting 1 in 375 boys. In hypospadias patients, the urethral opening is not located at the tip of the penis, but somewhere halfway, at the base of the penis, or even in the scrotum.

29 Nov 2010

ACS recommends annual MRI screening in women with family history of breast cancer

Women with a personal history of breast cancer should consider annual screening with MRI in addition to mammography, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

29 Nov 2010

Philips ushers new era in radiology science with Imaging 2.0 technology at RSNA annual meeting

This year at the 96th annual meeting of the Radiological Society of North America (RSNA) in Chicago, Royal Philips Electronics is ushering in a new era in radiology science with Imaging 2.0, a concept fueled by integration of technology, clinician and patient.

From Philips Healthcare 29 Nov 2010

New irreversible covalent approach to inhibit viral protease

Avila Therapeutics, Inc., a biotechnology company developing novel targeted covalent drugs, has published research in Nature Chemical Biology demonstrating the first-ever selective irreversible inhibition of a viral protease using a targeted covalent drug.

28 Nov 2010

New strategy to prevent memory deficits in mouse model with AD

Scientists at the Gladstone Institute of Neurological Disease (GIND) in San Francisco have discovered a new strategy to prevent memory deficits in a mouse model of Alzheimer's disease (AD).

28 Nov 2010

Researchers explain molecular mechanism that induces HER2+ tumours to ignore cell signals

About 30% of breast cancer patients have tumours that show rapid growth and invasion through the body. A common denominator in all of these cases is the presence of a large number of Her2 proteins in tumour cellular membranes. Consequently, these aggressive tumours are referred to as HER2+. Scientists working in the Metastasis Laboratory (MetLab) at IRB Barcelona headed by ICREA researcher Roger Gomis, have described the molecular mechanism that induces HER2+ tumours to ignore the signals that protect cells from excessive growth.

25 Nov 2010

Research finds ways to tackle drug resistance in melanoma

The past year has brought to light both the promise and the frustration of developing new drugs to treat melanoma, the most deadly form of skin cancer. Early clinical tests of a candidate drug aimed at a crucial cancer-causing gene revealed impressive results in patients whose cancers resisted all currently available treatments.

25 Nov 2010

Tension-dependent stabilization helps chromosome separation machinery

Scientists have discovered an amazingly simple way that cells stabilize their machinery for forcing apart chromosomes. Their findings are reported Nov. 25 in Nature.

25 Nov 2010

Response to PLX4032 drug short lived in BRAF-mutated metastatic melanoma patients

Researchers with UCLA's Jonsson Comprehensive Cancer Center have found that melanoma patients whose cancers are caused by mutation of the BRAF gene become resistant to a promising targeted treatment through another genetic mutation or the overexpression of a cell surface protein, both driving survival of the cancer and accounting for relapse.

25 Nov 2010

Discovery may lead to new generation of drugs to minimize heart attack risk

An international team led by researchers from the Universities of Leicester and Cambridge has announced a breakthrough in identifying people at risk of developing potentially fatal blood clots that can lead to heart attack.

24 Nov 2010

SIRS-Lab, Pfizer collaborate to improve patients’ outcome with sepsis

SIRS-Lab GmbH, a molecular diagnostics company based in Jena, Germany, and Pfizer Pharma GmbH, headquartered in Berlin, have announced a collaboration in the field of sepsis.

24 Nov 2010

Plant-derived bioscavenger protects against pesticide and nerve agent organophosphate poisoning

The brain is forever chattering to itself, via electrical impulses sent along its hard-wired neuronal "Ethernet." These e-messages are translated into chemical transmissions, allowing communication across the narrow cleft separating one neuron from another or between neurons and their target cells. Of the many kinds of molecules involved in this lively chemical symposium, acetylcholine is among the most critical, performing a host of functions in the central and peripheral nervous system.

24 Nov 2010

NIH expands genetic and clinical research database to provide access to digital study images

The National Institutes of Health has expanded a genetic and clinical research database to give researchers access to the first digital study images.

24 Nov 2010

Hepcidin hormone may be potential therapeutic tool for anemic blood disorders

A hormone made by the body may be a potential therapeutic tool for the treatment of two anemic blood disorders beta-thalassemia and hemochromatosis. The new research was led by scientists at Weill Cornell Medical College and published in the Journal of Clinical Investigation and the journal Blood.

24 Nov 2010

Gene News and Research

Latest Gene News and Research

Overexpression of microRNA 125b can cause leukemia: Research

Ageing reversed in mice: Study

Hemispherx requests FDA time extension for Ampligen NDA data resubmission

Depressed and suicidal individuals linked to low levels of stress hormone cortisol

QIAGEN to supply point-of-need molecular veterinary diagnostics for disease detection in emerging countries

Marcus evans Summit highlights potential growth, innovation in drug discovery

Study finds association between DGKK gene and hypospadias

ACS recommends annual MRI screening in women with family history of breast cancer

Philips ushers new era in radiology science with Imaging 2.0 technology at RSNA annual meeting

New irreversible covalent approach to inhibit viral protease

New strategy to prevent memory deficits in mouse model with AD

Researchers explain molecular mechanism that induces HER2+ tumours to ignore cell signals

Research finds ways to tackle drug resistance in melanoma

Tension-dependent stabilization helps chromosome separation machinery

Response to PLX4032 drug short lived in BRAF-mutated metastatic melanoma patients

Discovery may lead to new generation of drugs to minimize heart attack risk

SIRS-Lab, Pfizer collaborate to improve patients’ outcome with sepsis

Plant-derived bioscavenger protects against pesticide and nerve agent organophosphate poisoning

NIH expands genetic and clinical research database to provide access to digital study images

Hepcidin hormone may be potential therapeutic tool for anemic blood disorders

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