Gene News and Research

Latest Gene News and Research

Genes and alcoholism link explored: Study

According to the latest research in the U.S., a genetic variation may protect against alcoholism, and this could lead to a novel preventative treatment. The researchers say that a gene variant known as CYP2EI is linked to people's response to alcohol.

19 Oct 2010

Agendia establishes contract with Humana for coverage of MammaPrint breast cancer recurrence test

Agendia, a world leader in molecular cancer diagnostics, announced today that it has established a contract with leading insurance provider Humana to reimburse for the company's MammaPrint test. Agendia's contract with Humana expands the coverage for MammaPrint by more than 17 million lives. In November 2009, Palmetto GBA, California's Part B Medicare administrator, established coding guidelines for MammaPrint, allowing healthcare providers from across the United States to submit claims for the test.

19 Oct 2010

BioMarin announces BMN-111 program for treatment of achondroplasia

BioMarin Pharmaceutical Inc. today announced its program for BMN-111, a peptide therapeutic for the treatment of achondroplasia. BioMarin plans to file an IND in the fourth quarter of 2011 and to initiate a Phase 1 clinical trial by the first quarter of 2012.

19 Oct 2010

Pharmacy graduate awarded national recognition for pioneering research in genetics

A young pharmacy graduate has been awarded national recognition for her pioneering research in the field of genetics which has the potential to treat diseases such as cancer and Parkinson's.

19 Oct 2010

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

A team co-led by neuroscientists at Cold Spring Harbor Laboratory (CSHL) has shed light -- literally -- on circuitry underlying the olfactory system in mammals, giving us a new view of how that system may pull off some of its most amazing feats.

19 Oct 2010

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

The recently signed cooperation agreement between the MPI of Biochemistry and GSK pursues the objective of developing innovative new drugs. The joint research and development work is based on the research findings of Axel Ullrich, Director at the MPI of Biochemistry.

19 Oct 2010

Discovery of 4 new DNA 'hotspots' may aid in developing new therapies for psoriasis

Scientists at the University of Michigan Heath System and their collaborators have found four new DNA "hotspots" that may one day help guide new treatments for psoriasis, one of the most common autoimmune diseases in the country.

19 Oct 2010

New research coalition to design first human trial of mosaic HIV vaccine candidate

Duke University Medical Center vaccine experts have assembled an international team of investigators to design and implement the first human trial of a mosaic HIV vaccine candidate, a novel strategy that attempts to counter one of the most daunting challenges in HIV vaccine design: the virus's extensive genetic diversity

19 Oct 2010

Study finds IAP enzyme maintains normal microbial population in gastrointestinal system

An enzyme that keeps intestinal bacteria out of the bloodstream may also play an important role in maintaining the normal microbial population of the gastrointestinal system.

19 Oct 2010

Discovery may aid in developing new psoriasis therapies

Scientists at the University of Michigan Heath System and their collaborators have found four new DNA “hotspots” that may one day help guide new treatments for psoriasis, one of the most common autoimmune diseases in the country.

18 Oct 2010

Vertex commences VX-770 and VX-809 combination Phase 2a clinical trial for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced the initiation of a Phase 2a clinical trial that will evaluate multiple combinations of VX-770 and VX-809, investigational oral cystic fibrosis transmembrane conductance regulator (CFTR) modulators for the treatment of cystic fibrosis (CF). The trial is designed to evaluate the safety and tolerability of VX-809 dosed alone for 14 days followed by dosing of VX-809 in combination with VX-770 for 7 days.

18 Oct 2010

EC grants orphan drug designation to S*BIO's SB1518 for treatment of myelofibrosis

S*BIO Pte Ltd today announced that the European Commission (EC) has granted orphan drug designation to SB1518, its potent and orally active JAK2 inhibitor for the treatment of primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and post-essential thrombocythemia myelofibrosis (PET-MF). SB1518 has also received orphan drug designation from the U.S. Food and Drug Administration (FDA) for the treatment of the same disorder.

18 Oct 2010

Possibilities of genetics research, personalized medicine, and behavioral intervention

Personalized medicine - improving the fit between patient and treatment - has become a major focus of research in fields from cancer treatment to the psychopharmacology of mental disorders. Genetic studies have suggested that an individual's genetic makeup renders him either more or less sensitive to stressful social environments - but can an individual's unique genotype also determine the effectiveness of preventative or therapeutic behavioral interventions?

18 Oct 2010

Metabolon announces publication of metabolic analysis of biochemical changes in CF primary lung epithelial cells

Metabolon, Inc., the leader in global metabolomics, biomarker discovery and analysis, announces the publication of "Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells", in the Journal of Biological Chemistry.

18 Oct 2010

Major advance in treatment of brain disorders with external genes

In the October 17 issue of Nature Methods, researchers at Thomas Jefferson University describe how they can transfer genes into brain neurons intravenously, using a viral gene delivery vehicle (vector) that causes no side effects.

18 Oct 2010

Celgene acquires Abraxis BioScience

Celgene Corporation today announced it has completed its acquisition of Abraxis BioScience, Inc. For each share of Abraxis common stock, Abraxis shareholders will receive (i) $58.00 in cash (ii) 0.2617 shares of Celgene common stock, and (iii) one tradeable Contingent Value Right (CVR), which entitles its holder to receive a pro rata share of potential payments for future regulatory milestones and commercial royalties.

18 Oct 2010

Researchers identify new paradigm for regulation of alternative splicing

How a T cell decides to make protein X, Y, or Z can have profound effects for fighting foreign invaders or staving off dire autoimmune reactions. Researchers at the University of Pennsylvania School of Medicine have identified the steps that control how different forms of an immune cell protein called CD45, which is critical for activating the immune system when faced with pathogens, are controlled in the arc of a body's immune response.

18 Oct 2010

Researchers discover gene that contributes to depression

Yale University researchers have found a gene that seems to be a key contributor to the onset of depression and is a promising target for a new class of antidepressants, they report Oct. 17 in the journal Nature Medicine.

18 Oct 2010

Cempra to present data on solithromycin, TAKSTA at 48th Annual Meeting in Vancouver

Cempra Pharmaceuticals today announced poster presentations on its novel fluoroketolide antibiotic, solithromycin (CEM-101), and the Company's proprietary front-loading oral dosing regimen of sodium fusidate, TAKSTA (CEM-102) at the 48th Annual Meeting of the Infectious Diseases Society of America in Vancouver, British Columbia.

18 Oct 2010

Researchers discover blocking beta-arrestin 1 protein can reduce severity of heart failure

A Nova Southeastern University (NSU) researcher has announced a breakthrough discovery to block a protein that can contribute to heart failure. His discovery will appear in an upcoming issue of the prestigious medical journal, the Journal of the American College of Cardiology.

18 Oct 2010

Gene News and Research

Latest Gene News and Research

Genes and alcoholism link explored: Study

Agendia establishes contract with Humana for coverage of MammaPrint breast cancer recurrence test

BioMarin announces BMN-111 program for treatment of achondroplasia

Pharmacy graduate awarded national recognition for pioneering research in genetics

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

Discovery of 4 new DNA 'hotspots' may aid in developing new therapies for psoriasis

New research coalition to design first human trial of mosaic HIV vaccine candidate

Study finds IAP enzyme maintains normal microbial population in gastrointestinal system

Discovery may aid in developing new psoriasis therapies

Vertex commences VX-770 and VX-809 combination Phase 2a clinical trial for cystic fibrosis

EC grants orphan drug designation to S*BIO's SB1518 for treatment of myelofibrosis

Possibilities of genetics research, personalized medicine, and behavioral intervention

Metabolon announces publication of metabolic analysis of biochemical changes in CF primary lung epithelial cells

Major advance in treatment of brain disorders with external genes

Celgene acquires Abraxis BioScience

Researchers identify new paradigm for regulation of alternative splicing

Researchers discover gene that contributes to depression

Cempra to present data on solithromycin, TAKSTA at 48th Annual Meeting in Vancouver

Researchers discover blocking beta-arrestin 1 protein can reduce severity of heart failure

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