Gene News and Research

Latest Gene News and Research

New understanding on insulin resistance, action of diabetes drugs may lead to safer medication

A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say scientists from Dana-Farber Cancer Institute and The Scripps Research Institute.Our findings strongly suggest that good and bad effects of these drugs can be separated by designing second-generation drugs that focus on the newly uncovered mechanism, said Bruce Spiegelman, PhD, of Dana-Farber, senior author on a report appearing in the July 22 issue of Nature.

22 Jul 2010

Genomics researchers study role of protein in metabolic disorders, heart disease

Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.

22 Jul 2010

Scientists uncover new mechanism that reduces risk of type 2 diabetes, cardiovascular disease

In a joint study, scientists from The Scripps Research Institute and the Dana-Farber Cancer Institute at Harvard University have uncovered a novel mechanism that dramatically increases insulin sensitivity and reduces the risk of developing type 2 diabetes and cardiovascular disease.

22 Jul 2010

Affymetrix launches QuantiGene ViewRNA Assay formats

Affymetrix, Inc. today announced the launch of QuantiGene® ViewRNA Assay formats, which enable a new era of "in situ multiplex gene expression analysis" by allowing drug screening of native cells and advancing the pace of biomarker disease research and stem cell studies. These in situ assays enable researchers to visualize gene expression in individual cells at an unprecedented level of sensitivity and speed.

22 Jul 2010

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

22 Jul 2010

Smoking cessation effectively alter subgingival microbiome in patients on periodontal therapy: Study

Patients with chronic gum disease who quit smoking in addition to undergoing nonsurgical therapy not only demonstrated a lower abundance of harmful oral pathogens, but also an increase in health-associated bacteria. The researchers from The Ohio State University, Columbus Ohio, and Newcastle University, United Kingdom report their findings in the July 2010 issue of the Journal of Clinical Microbiology.

22 Jul 2010

Valproic acid halts vision loss in patients with retinitis pigmentosa

Researchers at the University of Massachusetts Medical School believe they may have found a new treatment for retinitis pigmentosa, a severe neurodegenerative disease of the retina that ultimately results in blindness. One of the more common retinal degenerative diseases, RP is caused by the death of photoreceptor cells and affects 1 in 4,000 people in the United States. RP typically manifests in young adulthood as night blindness or a loss of peripheral vision and in many cases progresses to legal blindness by age 40.

22 Jul 2010

Survey links autism with digestive problems, intestinal inflammation

Autism is the fastest growing developmental disorder in the world. With 1 child in 91 facing the disorder, the diagnosis is more common than pediatric cancer, diabetes, and AIDS combined.

22 Jul 2010

Affymetrix second-quarter total revenue decreases to $71.7 million

Affymetrix, Inc., today reported its operating results for the second quarter of 2010. Total revenue for the quarter was $71.7 million, in line with previously announced expectations, as compared to total revenue of $81.6 million in the second quarter of 2009.

22 Jul 2010

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

Eighty years ago, the medical establishment believed cancer was caused by a dysfunction of metabolism, but the idea went out of vogue. Now, scientists are again looking at metabolism and its role in cancer and other common diseases. Metabolism is a highly connected network of reactions that are arranged in parallel and interacting pathways. Such parallelism can mask how genes are linked with disease traits and make it difficult to treat conditions.

22 Jul 2010

New findings suggest link between increased cholesterol, depression

Most people know that high cholesterol levels place them at increased risk for heart disease and stroke. Prior research has shown that particular types of strokes contribute to one's risk for depression, and that abnormal blood lipid levels can increase the risk of depression in the elderly.

21 Jul 2010

Quest Diagnostics income from continuing operations increases to $195 million in second-quarter 2010

Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, announced that for the second quarter ended June 30, 2010, income from continuing operations increased to $195 million, or $1.07 per diluted share, compared to $188 million, or $1.00 per diluted share, in the second quarter of 2009. Results for 2009 included a benefit associated with an insurance recovery of $0.05 per share, offset by charges of $0.04 per share associated with the company's debt repurchase and an investment writeoff.

From Quest Diagnostics 21 Jul 2010

Gene essential for respiration and survival at birth identified

How do mammals prepare themselves in utero for a radical modification to their respiration at the time of birth, when they move abruptly from an aquatic medium to air? CNRS researchers, working in collaboration with teams from the Universities of the Méditerranée, Paris-Sud 11 and Paul Cézanne have identified a gene in the mouse that is essential to respiration and consequently to survival at birth.

21 Jul 2010

Roche, Exiqon join marketing forces for RealTime ready assays, microRNA PCR systems

Roche and Exiqon join marketing forces for Roche Applied Science's RealTime ready assays and Exiqon`s miRCURY LNA Universal RT microRNA qPCR system. As indicated by respective links on their websites, each system will complement the cooperator's product portfolio.

21 Jul 2010

INRA Genomic Platform core facility now provides services on Fluidigm's BioMark System for Genetic Analysis

Fluidigm Corporation today announced that the Toulouse Midi-Pyrénées Genomic Platform - Genotoul INRA core facility is now providing a wide range of services on a BioMark™ System for Genetic Analysis to a wide range of French researchers. These services include SNP genotyping, gene expression analysis and digital PCR quantification of DNA libraries for next-generation sequencing. The INRA has been validating the performance of the system on several projects over the past year.

21 Jul 2010

University of Luebeck becomes part of Metaminer Cardiac Partnership

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that Dr. Salah Mohamed in Department of Cardio and Thoracic Vascular Surgery at the University of Luebeck and his team will be part of the Metaminer Cardiac Partnership. Dr. Mohamed is published within 6 different reputed Scientific American Journals in connection with Biomarker Discovery work performed for the American Heart Association.

21 Jul 2010

Affymetrix introduces Axiom Custom Genotyping Arrays

Affymetrix, Inc. today announced that it has launched Axiom™ Custom Genotyping Arrays, the newest addition to the Axiom Genotyping Solution. Researchers can now leverage Affymetrix' Axiom Genomic Database, the world's largest collection of validated common and rare SNPs, to create custom arrays containing 50,000 to as many as 2.6 million SNPs. This inherent flexibility allows researchers to conduct genome-wide association, replication, fine mapping, and candidate gene studies on a single platform.

21 Jul 2010

Researchers receive $12M NCI grant to identify biological pathways that lead to prostate cancer risk

Researchers at the USC Norris Comprehensive Cancer Center have received a $12 million National Cancer Institute grant to lead a multi-institution international project aimed at identifying new biological pathways critical to the development and potential treatment of prostate cancer.

21 Jul 2010

La Jolla Institute forms partnership to investigate potential new therapy for sickle cell disease

Researchers from the La Jolla Institute for Allergy & Immunology have joined forces with the Dana-Farber Cancer Institute in Boston and Washington University in St. Louis to investigate a potential new therapy for sickle cell disease, a severe and chronic illness affecting more than 70,000 Americans and several million people worldwide.

21 Jul 2010

CHLA receives $410,000 grant for 'first in childhood leukemia' multi-site study

J. Eric Bubbers, PhD, of the Saban Research Institute at Childrens Hospital Los Angeles, has received a $410,000 grant from Phase One Foundation. The award will fund a "first in childhood leukemia" multi-site study in children with relapsed or refractory acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML). Dr. Bubbers is the administrative director of Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL), an academic research consortium consisting of 33 member institutions in four countries.

21 Jul 2010

Gene News and Research

Latest Gene News and Research

New understanding on insulin resistance, action of diabetes drugs may lead to safer medication

Genomics researchers study role of protein in metabolic disorders, heart disease

Scientists uncover new mechanism that reduces risk of type 2 diabetes, cardiovascular disease

Affymetrix launches QuantiGene ViewRNA Assay formats

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

Smoking cessation effectively alter subgingival microbiome in patients on periodontal therapy: Study

Valproic acid halts vision loss in patients with retinitis pigmentosa

Survey links autism with digestive problems, intestinal inflammation

Affymetrix second-quarter total revenue decreases to $71.7 million

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

New findings suggest link between increased cholesterol, depression

Quest Diagnostics income from continuing operations increases to $195 million in second-quarter 2010

Gene essential for respiration and survival at birth identified

Roche, Exiqon join marketing forces for RealTime ready assays, microRNA PCR systems

INRA Genomic Platform core facility now provides services on Fluidigm's BioMark System for Genetic Analysis

University of Luebeck becomes part of Metaminer Cardiac Partnership

Affymetrix introduces Axiom Custom Genotyping Arrays

Researchers receive $12M NCI grant to identify biological pathways that lead to prostate cancer risk

La Jolla Institute forms partnership to investigate potential new therapy for sickle cell disease

CHLA receives $410,000 grant for 'first in childhood leukemia' multi-site study

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