Gene News and Research

Latest Gene News and Research

UCSF transgenic mouse model first to display earliest signs of Parkinson's disease

UCSF researchers have created the first transgenic mouse to display the earliest signs of Parkinson's disease using the genetic mutation that is known to accompany human forms of the disease.

4 May 2010

New data on salt-sensitive hypertension to be presented at ASH 2010 conference

With governmental authorities, academicians, healthcare providers and industry grappling with the level of salt in the diet in an effort to reduce its impact on high blood pressure, new data evaluating a potential genetic component to salt-sensitive hypertension will be presented at the American Society of Hypertension, Inc.'s 25th Annual Scientific Meeting and Exposition (ASH 2010).

4 May 2010

Neural stem cell transplantation promising for Batten disease

Neuronal Ceroid Liposfuscinosis (NCL), often referred to as Batten disease, is a rare and fatal neurodegenerative disorder that afflicts infants and young children. NCL is caused by a deficiency of a lysosomal enzyme, and is a relatively rare disease, affecting an estimated 2 to 4 of every 100,000 babies born in the U.S. Although NCLs are classified as rare diseases, they often affect more than one child in families that carry the defective gene, and tragically, are always fatal.

4 May 2010

Hormone-like inner ear signaling system protects against noise-induced hearing loss

An in vivo study shows for the first time that there is a stress-response system within the cochlea that mirrors the signaling pathways of the body's fight or flight response. Researchers have identified a hormone-like signaling system of the inner ear that sets baseline hearing sensitivity and helps protect against noise-induced hearing loss.

4 May 2010

New breakthrough in nutritional plant breeding may save children’s eyesight

Two Agricultural Research Service (ARS) scientists are part of an international team that has found a way to boost the nutritional value of corn. This has the potential to reduce the number of children in developing countries who lose their eyesight, become ill or die each year because of vitamin A deficiencies.

4 May 2010

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Gaucher disease, a rare enzyme deficiency disorder, is one of many conditions with few approved treatment options for patients. In a study published online today in Blood, the journal of the American Society of Hematology, researchers present positive results of a Phase II clinical trial of eliglustat tartrate, an oral therapy in development to treat Gaucher disease.

4 May 2010

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

Whitehead Institute researchers have converted established human induced pluripotent stem cells and human embryonic stem cells to a base state of greater pluripotency.

4 May 2010

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

The National Institutes of Health has awarded $10.24 million to Fred Hutchinson Cancer Research Center to lead a five-year study that aims to understand and prevent breast cancer disparities in Hispanic women.

4 May 2010

QIAGEN reports 20% revenue growth in first quarter 2010

QIAGEN N.V. today announced the results of operations for its quarter ended March 31, 2010. Net sales were at the high end of, and adjusted earnings per share for the first quarter 2010 exceeded the guidance provided by the Company on February 9, 2010.

From QIAGEN Manchester Limited 4 May 2010

Researchers identify genes associated with cleft lip and/or cleft palate

An international consortium of scientists, led by researchers at Johns Hopkins University has identified two genes that when altered are closely associated with cleft lip and/or cleft palate. Cleft lip and cleft palate are among the world's most common congenital malformations and occur in one in every 700 births. The finding is the result of the largest family-based, genome-wide study of cleft lip and/or cleft palate conducted to date. The results were published online by the journal Nature Genetics.

3 May 2010

HTG, JWCI collaborate to develop new approaches for early stage primary cutaneous melanoma diagnosis

HTG, Inc., provider of the quantitative Nuclease Protection Assay (qNPA™), today announced it signed a collaboration agreement with the John Wayne Cancer Institute (JWCI) at Saint John's Health Center in Santa Monica, California. Under the terms of the agreement, HTG and JWCI (Department of Molecular Oncology, Dave S. B. Hoon, Ph.D., Director) will collaborate to generate a novel mRNA signature that can measure the gene expression differences in melanoma and benign nevi using HTG's qNPA technology in classical surgical pathology samples.

3 May 2010

Progress in development of gene therapies for inherited blindness caused by rod degeneration

Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.

3 May 2010

Scientist to receive 2010 March of Dimes Prize in Developmental Biology

The scientist who reprogrammed adult cells into embryonic-like stem cells has been chosen to receive the 2010 March of Dimes Prize in Developmental Biology.

3 May 2010

Protein test to determine response of lung cancer patients to erlotinib

Testing for the presence of specific cancer protein 'fingerprints' in the blood of lung cancer patients may be a useful means of identifying a subgroup whose tumors are more likely to shrink when treated with the drug erlotinib, especially when other testing methods are unavailable, according to new data presented at the 2nd European Lung Cancer Conference in Geneva, Switzerland.

3 May 2010

Scientists discover two body clock genes that may help find treatments for seasonal affective disorder

Scientists have discovered two "body clock" genes that reveal how seasonal changes in hormones are controlled and could ultimately help find treatments for seasonal affective disorder.

3 May 2010

Study indicates older women with diabetes have increase risk for colon cancer

A research team led by Mayo Clinic physicians has found that older women with diabetes face a more than doubled risk for some types of colorectal cancer.

3 May 2010

Majority of patients who appear healthy may be at risk for cardiovascular disease

Three separate studies announced today at the American Society of Hypertension Inc.'s 25th Annual Scientific Meeting and Exposition (ASH 2010) examined the cardiovascular consequences of relatively healthy patients - those who were asymptomatic and not classified as hypertensive or diabetic - and found that many patients who appear healthy may still be at risk for cardiovascular disease.

3 May 2010

Scientists discover three genes linked to development of Paget's disease

Scientists have discovered three genes linked to the development of Paget's disease, a painful bone condition that affects up to one million people in the UK.

3 May 2010

Mutations in several genes associated with developmental brain disorder: Study

Although there is no known cause of autism, studies have shown that mutations in several genes are associated with the developmental brain disorder. New research has uncovered two additional genes that may be involved with autism.

3 May 2010

McGill scientist discovers how one particular gene regulates epithelial cells

New research led by McGill Biochemist Dr. William Muller helps explain why breast-milk cells lose their structure, causing them to clump up in strange ways (photos available) and sometimes become cancer tumors. With the support of Chen Ling and Dongmei Zuo at McGill's Goodman Cancer Centre, Muller has discovered how one particular gene regulates epithelial cells - cells that normally form in sheets and are polarized to enable the transport of molecules in a single direction.

30 Apr 2010

Gene News and Research

Latest Gene News and Research

UCSF transgenic mouse model first to display earliest signs of Parkinson's disease

New data on salt-sensitive hypertension to be presented at ASH 2010 conference

Neural stem cell transplantation promising for Batten disease

Hormone-like inner ear signaling system protects against noise-induced hearing loss

New breakthrough in nutritional plant breeding may save children’s eyesight

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

QIAGEN reports 20% revenue growth in first quarter 2010

Researchers identify genes associated with cleft lip and/or cleft palate

HTG, JWCI collaborate to develop new approaches for early stage primary cutaneous melanoma diagnosis

Progress in development of gene therapies for inherited blindness caused by rod degeneration

Scientist to receive 2010 March of Dimes Prize in Developmental Biology

Protein test to determine response of lung cancer patients to erlotinib

Scientists discover two body clock genes that may help find treatments for seasonal affective disorder

Study indicates older women with diabetes have increase risk for colon cancer

Majority of patients who appear healthy may be at risk for cardiovascular disease

Scientists discover three genes linked to development of Paget's disease

Mutations in several genes associated with developmental brain disorder: Study

McGill scientist discovers how one particular gene regulates epithelial cells

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