Gene News and Research

Latest Gene News and Research

Startling discovery on the development of human embryonic stem cells

In this week's Nature, researchers of the McMaster Cancer and Stem Cell Research Institute show that human embryonic stem (ES) cells can actually produce distinctive niche cells, which then release stem-cell nourishing proteins to help keep their parents ticking over.

12 Jul 2007

New method to estimate sickle cell disease severity

Researchers from Boston University School of Medicine (BUSM) and Boston University School of Public Health (BUSPH) have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease.

12 Jul 2007

New evidence of very recent human adaptation

A Cornell study of genome sequences in African-Americans, European-Americans and Chinese suggests that natural selection has caused as much as 10 percent of the human genome to change in some populations in the last 15,000 to 100,000 years, when people began migrating from Africa.

12 Jul 2007

Chemotherapy may benefit all women with a BRCA1 mutation

Breast cancer patients who possess one of the so-called "breast cancer" or BRCA genetic mutations do not have a higher risk of dying than patients with no BRCA mutations, according to a detailed study by researchers at the Technion-Israel Institute of Technology and the University of Toronto.

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

Ago2 and hematopoiesis

Argonaute 2 (Ago2) is unique among its family: It is the only one of the four mammalian Argonaute proteins that exhibits endonuclease 'slicer' activity (facilitation of miRNA-guided cleavage of target mRNA).

12 Jul 2007

New model of early biological evolution

In a study publishing in PLoS Computational Biology, Shakhnovich et al present a new model of early biological evolution , the first that directly relates the fitness of a population of evolving model organisms to the properties of their proteins.

12 Jul 2007

New genetic function involved in embryo development in organisms

Research aimed at understanding the mechanisms underlying embryo development has taken a step forward thanks to collaborative work between biologists specialized in the study of the fruit fly (Drosophila melanogaster) and scientists specialized in the design of mathematical models that simulate the functioning of biological systems.

11 Jul 2007

Master switch for the production of brown fat discovered

Researchers at Dana-Farber Cancer Institute have identified a long-sought "master switch" in mice for the production of brown fat, a type of adipose tissue that generates heat and counters obesity caused by overeating.

11 Jul 2007

Neural stem cells for Parkinson's disease

A University of South Florida neuroscientist reports that the cutting-edge research study of human stem cells in primates with Parkinson's disease is compelling on several fronts , particularly how the transplanted cells did their job of easing disease symptoms.

11 Jul 2007

Discovery of gallstone gene

Scientists at the University of Bonn, together with colleagues from Romania, have discovered a gene variant that significantly increases the risk of developing gallstones (Hepatology No. 46, 11 July 2007, DOI 10.1002/hep.21847).

11 Jul 2007

3-D microscopic views of tiny mouse brains available online

A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains - unveiled layer by layer - by extending the capabilities of conventional magnetic resonance imaging.

10 Jul 2007

Magnetic nano tweezers show how cancer drug works

The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller's motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at St. Jude Children's Research Hospital and Delft University of Technology.

10 Jul 2007

New insights into acute promyelocytic leukemia

Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.

10 Jul 2007

Rapid evolution of defense genes in plants may produce hybrid incompatibility

One of the basic tenets of evolution is speciation in which populations of the same species become so genetically and morphologically variable that they can be classified as two different species.

10 Jul 2007

Researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression.

10 Jul 2007

New gene mutation linked to frontotemporal dementia

Researchers have identified a new gene mutation linked to frontotemporal dementia, according to a study published in the July 10, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

10 Jul 2007

Neutral genetic drift

Johns Hopkins researchers have added to the growing mound of evidence that many of the genetic bits and pieces that drive evolutionary changes do not confer any advantages or disadvantages to humans or other animals.

10 Jul 2007

Bacterial biofilms

In one of the first potential applications of synthetic biology, an emerging field that aims to design and build useful biomolecular systems, researchers from MIT and Boston University are engineering viruses to attack and destroy the surface biofilms that harbor harmful bacteria in the body and on industrial and medical devices.

10 Jul 2007

Breast cancers to be more aggressive in African-American women

A study of more than 2,200 women at the Kimmel Cancer Center at Jefferson in Philadelphia shows that African American women have more advanced breast cancer at the time of diagnosis than Caucasian women.

10 Jul 2007