Gene News and Research

Latest Gene News and Research

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

Scientists discover new mechanism for viral replication

Researchers at the University of Pennsylvania School of Medicine have identified a new strategy that Kaposi's Sarcoma Associated Herpesvirus (KSHV) uses to dupe infected cells into replicating its viral genome.

17 Aug 2007

Researchers discover how a protein modulates the inflammatory response in acute respiratory distress syndrome

Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure.

17 Aug 2007

FDA approves updated labeling for Warfarin (Coumadin)

The U.S. Food and Drug Administration has announced the approval of updated labeling for the widely used blood-thinning drug, Coumadin, to explain that people's genetic makeup may influence how they respond to the drug.

17 Aug 2007

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned

Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.

17 Aug 2007

New findings on cholesterol metabolism

A team of researchers investigating cholesterol and lipid transport has performed experiments that cast serious doubt on the dominant hypothesis of how the body rids its cells of "bad" cholesterol (LDL) and increases "good" cholesterol (HDL).

17 Aug 2007

New insight into fragile X tremor/ataxia syndrome

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome.

17 Aug 2007

Metformin kills some cancer cells

Researchers at the University of Pennsylvania School of Medicine have found that a commonly prescribed diabetes drug kills tumor cells that lack a key regulatory gene called p53.

16 Aug 2007

Caution urged on use of drugs to raise "good" cholesterol

With 40 percent of all heart attacks and related cardiovascular problems occurring in people who have low levels of so-called "good" cholesterol, researchers have long sought medications to increase the amount of this type of cholesterol in the body's circulation.

16 Aug 2007

Methamphetamine use has long-term behavioral consequences

Young adults who use methamphetamine may be more vulnerable to age-related brain degeneration when they grow older, new animal research suggests.

16 Aug 2007

Breast cancer prevention practices vary across Canada

Breast cancer preventive practices for Canadian women carrying the cancer gene vary across the country, says University of Toronto research, and many women are not taking advantage of the options available.

16 Aug 2007

Cancer blocking gene discovered

Canadian scientists have discovered a gene that suppresses the growth of many cancerous tumours.

14 Aug 2007

Discovery of new mechanism of resistance to endocrine or anti-hormonal therapies

When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye.

13 Aug 2007

Green tea for cancer prevention

Concentrated chemicals derived from green tea dramatically boosted production of a group of key detoxification enzymes in people with low levels of these beneficial proteins, according to researchers at Arizona Cancer Center.

13 Aug 2007

Gene use sets humans and chimps apart

The striking differences between humans and chimps aren't so much in the genes we have, which are 99 percent the same, but in the way those genes are used, according to new research from a Duke University team.

13 Aug 2007

Genomic factors may play a role in alcohol and tobacco use

Alcohol and smoking can be harmful, if not deadly. While the desire for these substances can be due to environmental cues, genomic factors also play an important role.

13 Aug 2007

Genetic engineering offers promising new approaches to improve dietary iron intake

Using selective plant breeding and genetic engineering could be used to reduce the incidence of iron deficiency worldwide by improving the quality of dietary iron, conclude authors of a Seminar in this week’s edition of The Lancet.

13 Aug 2007

New drug targets for multiple myeloma

Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.

13 Aug 2007