Gene News and Research

Latest Gene News and Research

Math1 gene plays a pivotal role in the formation of many of the neurons important in hearing and balance

Close your eyes and imagine you are in a darkened Carnegie Hall. Although it's pitch black, you know you are getting closer to the stage as the music gets louder. If you have been there before, you have a sense of the location of the seats and aisles.

5 Oct 2005

GRK5 protein plays important role in hypertension

Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.

5 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Divalent metal transporter-1 decreases metal-related injury in the lung

Multi-vitamin products, nutritional supplements and parents tout the need for such mineral elements as calcium, zinc, phosphorus, iron and others.

4 Oct 2005

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice resulting in a range of abnormalities, from cyclical hair loss and skin cancer to severe problems in normal skin development.

4 Oct 2005

New light shed on the causes of drug addiction

A methamphetamine epidemic rages across the United States with addicts blinded by uncontrollable desires for a drug that eventually thrusts them into a dire and catastrophic existence. Doctors don't have any effective treatments for these addicts, or for any other drug addicts; drug addiction is a disease that remains a medical mystery.

4 Oct 2005

Mechanism of X-chromosome dosage compensation in Drosophila

In Drosophila, like in humans, male cells have a single X chromosome, while female cells have two. Researchers have long debated over how X and autosomal chromosome gene expression is equalized between the sexes (generally regarding two different models, known as the activation model and the inverse model).

4 Oct 2005

Largest systematic analysis of duplicated gene function to date

When Mother Nature creates an identical copy of a gene in an organism's genome, the duplicated copy is usually deleted, inactivated, or otherwise rendered nonfunctional in order to prevent genetic redundancy and to preserve biological homeostasis. In some cases, however, gene duplicates are maintained in a functional state.

4 Oct 2005

Bacteria of different species can talk to each other using a common language

The interspecies crosstalk and misdirection could have important consequences for human health, said Bonnie L. Bassler, an HHMI investigator at Princeton University whose study was published in the September 29, 2005, issue of Nature.

4 Oct 2005

Body's own defenses may cause HIV-related dementia

Publishing in the Sept. 2005 issue of the Journal of Virology, the researchers show that HIV in the temporal lobe mutates at a rate 100 times faster than in other parts of the body, triggering white blood cells to continually swarm to attack the infection. The associated overcrowding and inflammation appear to cause the dementia.

3 Oct 2005

Scientists measure with unprecedented accuracy the strengths of hydrogen bonds in a protein

The scientists were then able to predict the function of different versions of the protein based on structural information, a novel outcome that was published recently in the Proceedings of the National Academy of Sciences.

3 Oct 2005

Computer model shows biochemical variations, or noise, leads to oscillations in gene regulation that couldn't otherwise be predicted

Geneticists have debated for decades the relative importance of nature versus nurture in determining how an animal looks and behaves, and now University of California, San Diego (UCSD) scientists report that noise could also be an important factor in determining phenotype.

3 Oct 2005

Discovery establishes a role for the gene Rsf-1 in ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers have linked alterations in a gene, called Rsf-1, to the most deadly ovarian cancers. The scientists say the discovery is the first to establish a role for the gene in ovarian cancer and may lead to a test that can predict, early on, which patients will develop aggressive disease.

3 Oct 2005

New genes tied to lifespan extension

Drastically reducing calorie intake, or caloric restriction, is known to extend the lifespan of species including yeast, worms and rodents. Previous research linked a gene called Sir2 with lifespan extension due to caloric restriction, but worms and yeast that lack Sir2 also live longer when put on a tough diet, showing that some other genes must be at work.

3 Oct 2005

Microarray technology may help tailor breast cancer therapy

Microarray technology could be used to tailor therapy according to the individual, and prevent breast cancer patients from having to undergo painful unsuccessful therapies.

3 Oct 2005

Stem cells help regenerate cartilage and bone

UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells.

28 Sep 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Common form of thalassaemia can be managed without blood transfusion

Haemoglobin E â thalassaemia - the commonest form of severe thalassaemia in many Asian countries - can be managed without transfusion in many patients, suggests a research letter published online today (Thursday September 29, 2005) by The Lancet.

28 Sep 2005

Pain-free needles!

Millions of fearful patients could be saved the pain of vaccinations thanks to revolutionary pain-free needles to be revealed today for the first time at the British Pharmaceutical Conference in Manchester.

28 Sep 2005