Gene News and Research

Latest Gene News and Research

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production

New research in Cell Metabolism identifies a key player in the body's ability to respond to insulin action in the brain by ratcheting down the export of blood sugar from the liver.

6 Apr 2006

Caenorhabditis elegans helps unravel mechanisms of hunger

In research that may have implications for studying eating disorders in humans, a worm the size of a pinhead is helping researchers at UT Southwestern Medical Center unravel the mechanisms of hunger.

6 Apr 2006

Researchers identify potential targets for more effective analgesic drugs with potentially fewer side effects

Studying mice, pain researchers at Washington University School of Medicine in St. Louis have identified two key components in the pain cascade that may provide targets for more effective analgesic drugs with potentially fewer side effects

6 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Ingredient in red peppers inhibits prostate cancer in laboratory studies

Capsaicin is the pungent ingredient in red peppers and is presently used as a topical pain reliever. Now, a new study shows it may be justified to evaluate capsaicin for inhibiting prostate cancer (CaP) in patients.

5 Apr 2006

Higher self awareness of memory difficulties may be associated with brain function decline over time

Published in the April issue of the Archives of General Psychiatry, the study offers a greater understanding of how different types and varying degrees of memory complaints may relate to brain function decline, a finding that may lead to early treatment interventions for people who could develop Alzheimer's disease.

4 Apr 2006

Genome evolution in gibbons erased fat gene

Scientists from The University of Tokyo have discovered that gibbons, arboreal primates that inhabit the jungles of Southeast Asia, do not carry a major obesity gene that is present in the genomes of all other primates, including humans.

4 Apr 2006

Genetic clues to longevity

In a new study, Drs. Gil Atzmon and Nir Barzilai at the Albert Einstein College of Medicine of Yeshiva University have found that people harbor alleles--alternative forms of a gene--that confer the same sort of longevity advantage.

4 Apr 2006

Nrf2 gene findings may offer therapeutic potential for sepsis treatment

Disruption of a single gene, Nrf2, plays a critical role in regulating the body's innate immune response to sepsis and septic shock, according to a study by a research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health.

4 Apr 2006

Johns Hopkins scientists identify genes in fruitflies that may shed light on human cancer spread

By searching through all the genes in the fruitfly genome, Johns Hopkins scientists have identified those required for a certain type of cell migration and simultaneously captured a global view of all the genes turned on when cells are on the move.

4 Apr 2006

Researchers narrow search for effective prostate cancer biomarkers

Researchers at Mayo Clinic have narrowed the search for effective prostate cancer biomarkers (genetic variations that point to a specific disease or condition), identifying changes in the expression of genes of the whole genome closely correlated to prostate cancer development and progression.

4 Apr 2006

People with very agile minds tend to have a very agile cortex

Youth with superior IQ are distinguished by how fast the thinking part of their brains thickens and thins as they grow up, researchers at the National Institute of Mental Health (NIMH) have discovered.

4 Apr 2006

HOXB13 and IL17BR genes predict outcome for breast cancer patients

The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.

4 Apr 2006

Immune response protects against brain tumor development

In their quest to determine whether immune system surveillance guards against brain tumor development, researchers at The University of Texas M. D. Anderson Cancer Center have found that allergies and asthma that stimulate inflammation may be protective, but use of antihistamines to control the inflammation could eliminate that protection.

4 Apr 2006

Mitochondria induce nuclear deformation

In a paper being presented in two American Physiological Society sessions at Experimental Biology 2006, a joint Estonian-French team demonstrated "for the first time that mitochondria are able to induce nuclear deformation, suggesting that mitochondria may mechanically regulate nuclear function."

4 Apr 2006

Proteomics yields new drug targets for treating cardiogenic shock

When it comes to cell signaling and bioregulation, it's tough to find a more important molecule than nitric oxide (NO). Dysfunction of NO-mediated signaling is thought to be a culprit in lethal cardiovascular conditions such as angina, and septic, cardiogenic and hemorrhagic shock; it may play a role in many other illnesses as well.

3 Apr 2006

Gene key to infection-fighting immune cells identified

Every time the human body encounters a virus, bacteria or other infectious agent, immune cells called B-lymphocytes multiply in lymph nodes and then swing into action to fight off the intruders.

3 Apr 2006

Weill Cornell experts publish review of genetic medicine

In an article published in the April issue of Nature Reviews Genetics, two experts at the Weill Medical College of Cornell University sum up the achievements, challenges and promise of a burgeoning field: genetic medicine.

3 Apr 2006

Malaria, mosquitoes and man - breaking a deadly cycle

Malaria kills a child every thirty seconds in Sub-Saharan Africa, according to recent estimates. It is a huge problem currently threatening over 40% of the world’s population and still on the increase.

31 Mar 2006

Scientists identify a new gene that causes the spread of cancer

Professor Philip Rudland, Dr Guozheng Wang and Dr Roger Barraclough from the University’s Cancer and Polio Research Fund Laboratories have discovered an additional member of the S100 family of protein genes - S100P - that causes the spread of cancerous cells from an original tumour to other parts of the body.

30 Mar 2006