Gene News and Research

Latest Gene News and Research

Mouse model of Rett Syndrome displays reduced cortical activity

Sacha Nelson of Brandeis University in Waltham, MA and Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA and their colleagues report online in the Proceedings of the National Academy of Sciences Early Edition that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood neurodevelopmental disorder, Rett Syndrome.

23 Aug 2005

First study to test the role of RNA chemical modifications on immunity

The investigators published their findings in the August issue of Immunity. "We think this study will open a new area of research in understanding how our immune systems protect us," says Weissman.

23 Aug 2005

State-of-the-art portable biosensing device based on micro and nanotechnologies

A state-of-the-art portable biosensing device based on micro- and nanotechnologies will empower doctors to rapidly and accurately forewarn patients of their genetic risk of developing diseases such as cancer.

23 Aug 2005

Novel mechanism, called recursive splicing reveals how cells process large genes

Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns).

22 Aug 2005

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Discovery of a potential oncogene in ovarian cancer

Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.

22 Aug 2005

Malfunctioning bone marrow cells cause neuropathy in many people with diabetes

Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine (BCM) in Houston.

22 Aug 2005

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function.

22 Aug 2005

Novel vaccine strain with high efficacy against tuberculosis

Tuberculosis remains a major global health threat. Although more than 3 billion doses of the BCG vaccine have been administered to fight tuberculosis, the ability of the BCG vaccine to protect adults is very limited, as is its efficacy against newly emerging isolates.

22 Aug 2005

Discovery of new gene FANCM sheds light on repair of damaged DNA

National Institute on Aging (NIA) researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA.

22 Aug 2005

Losing weight cuts breast cancer risk

An international team of scientists has found that young women who carry a breast cancer gene, can reduce their risk of the disease by up to 65% by attaining a healthy bodyweight.

21 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Loss of a gene called p63 accelerates aging in mice

Researchers have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes.

17 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Discovery of gene that controls the speed at which patients develop tuberculosis

Scientists at the Research Institute of the McGill University Health Centre (RI MUHC) have discovered a gene that controls the speed at which patients develop tuberculosis--the first time such a gene has been discovered for this disease.

16 Aug 2005

Gene expression levels may reveal stage of Huntington's disease

A survey of the genome of patients with Huntington's Disease (HD) has identified potential markers of the progression of this devastating neurological disorder.

16 Aug 2005

Researchers have discovered a gene linked to age-related maculopathy

University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.

16 Aug 2005

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said.

16 Aug 2005

Gene News and Research

Latest Gene News and Research

Mouse model of Rett Syndrome displays reduced cortical activity

First study to test the role of RNA chemical modifications on immunity

State-of-the-art portable biosensing device based on micro and nanotechnologies

Novel mechanism, called recursive splicing reveals how cells process large genes

Gene therapy advance shows potential for developing improved treatment for hemophilia

Discovery of a potential oncogene in ovarian cancer

Malfunctioning bone marrow cells cause neuropathy in many people with diabetes

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

Novel vaccine strain with high efficacy against tuberculosis

Discovery of new gene FANCM sheds light on repair of damaged DNA

Losing weight cuts breast cancer risk

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

Protein Sirt1 points to new therapies for type 2 diabetes

Defects in newly discovered pathway may be an overlooked cause of anemia

Loss of a gene called p63 accelerates aging in mice

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Discovery of gene that controls the speed at which patients develop tuberculosis

Gene expression levels may reveal stage of Huntington's disease

Researchers have discovered a gene linked to age-related maculopathy

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

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