Gene News and Research

Latest Gene News and Research

New Drug Application with the U.S. Food and Drug Administration for Tarceva

OSI Pharmaceuticals and Genentech have announced that OSI completed the submission of a New Drug Application with the U.S. Food and Drug Administration for Tarceva (erlotinib HCl),

3 Aug 2004

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

Scientists have developed a new screening technique to help them look for genes that change patients' responses to cancer drugs and other medications.

3 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before HIV

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before the emergence of HIV, according to new findings from Fred Hutchinson Cancer Research Center.

2 Aug 2004

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Genentech and XOMA have announced preliminary 30-month (120 weeks) results from an open-label study evaluating the safety and efficacy of long-term continuous treatment with RAPTIVA® (efalizumab) in adults with moderate-to-severe chronic plaque psoriasis.

2 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Twin research reveals gene that may play a crucial part in the development of myopia

New research carried out by doctors in the Twin Research Unit at St Thomas’ Hospital, London, indicates that a gene called PAX6 may play a crucial part in the development of myopia.

31 Jul 2004

Important step in understanding the genetic mechanisms of aging

Scientists have rendered the first gene and protein networks of human aging, an important step in understanding the genetic mechanisms of aging. The work led by Joao Pedro de Magalhaes from Harvard Medical School is detailed in the July 30 issue of FEBS Letters.

29 Jul 2004

Research to develop ways to inhibit head and neck cancers, the fifth most common cancer worldwide

A University of Queensland researcher has been awarded $850,000 by one of Australia’s largest private, charitable, medical foundations to develop ways to inhibit head and neck cancers, the fifth most common cancer worldwide.

29 Jul 2004

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

MDA-supported researchers at the University of Washington-Seattle have delivered the gene for the dystrophin protein to all voluntary muscles with a single intravenous injection in mice with Duchenne muscular dystrophy (DMD).

29 Jul 2004

Patent pending botanical extract, V38-AMF-1, completely inhibits bird flu (H5N1) and Fujian Flu

PRB Pharmaceuticals and Lee's Pharmaceuticals have announced the discovery that PRB'S patent pending botanical extract, V38-AMF-1, completely inhibits bird flu (H5N1) and Fujian Flu (H3N2) infections in vitro.

29 Jul 2004

Further evidence about how estrogen helps activate breast cancer

A UC Irvine researcher has found a novel tumor- suppressor function for a gene that, when mutated, often triggers breast cancer in women.

29 Jul 2004

Framework for systematically incorporating epigenetic information into traditional genetic studies

Scientists at Johns Hopkins are calling for simultaneous evaluation of both genetic and epigenetic information in the search to understand contributors to such common diseases as cancer, heart disease and diabetes.

29 Jul 2004

First tool to study image brain function at the cellular level

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

29 Jul 2004

New process that simplifies the production of proteins

F. William Studier, a biophysicist at the U.S. Department of Energy's Brookhaven National Laboratory, has won a 2004 R&D 100 award for developing a new process that simplifies the production of proteins in the widely used T7 gene expression system.

29 Jul 2004

Possible inherited component for lung cancer

Researchers have discovered a possible inherited component for lung cancer, a disease normally associated with external causes, such as cigarette smoking.

27 Jul 2004

Gene responsible for infertility

A paper describing discoveries about the role of a gene that is important in all animals, plants, and fungi is published in the 20 July 2004 issue of the journal Proceedings of the National Academy of Sciences.

23 Jul 2004

Gene associated with susceptibility to developing type 1 diabetes

A new gene mutation identified by researchers at Baylor College of Medicine in Houston is part of the constellation of genes associated with susceptibility to developing type 1 diabetes. It could also play a role in the devastating complications of diabetes such as kidney failure.

23 Jul 2004

$1.6 million to develop gene therapy strategies for Duchenne muscular dystrophy, a fatal, childhood-onset disease

The Muscular Dystrophy Association has announced it has awarded $1.6 million to Asklepios, a biotechnology company closely allied with the University of North Carolina at Chapel Hill, to develop gene therapy strategies for Duchenne muscular dystrophy (DMD), a fatal, childhood-onset disease.

23 Jul 2004

Gene News and Research

Latest Gene News and Research

New Drug Application with the U.S. Food and Drug Administration for Tarceva

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

A protein that the body uses to attack the AIDS virus is actually a stealthy defense mechanism that evolved 32 million years before HIV

Clinical benefit for moderate-to-severe plaque psoriasis patients treated with Raptiva for 30 months

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Twin research reveals gene that may play a crucial part in the development of myopia

Important step in understanding the genetic mechanisms of aging

Research to develop ways to inhibit head and neck cancers, the fifth most common cancer worldwide

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

Patent pending botanical extract, V38-AMF-1, completely inhibits bird flu (H5N1) and Fujian Flu

Further evidence about how estrogen helps activate breast cancer

Framework for systematically incorporating epigenetic information into traditional genetic studies

First tool to study image brain function at the cellular level

New process that simplifies the production of proteins

Possible inherited component for lung cancer

Gene responsible for infertility

Gene associated with susceptibility to developing type 1 diabetes

$1.6 million to develop gene therapy strategies for Duchenne muscular dystrophy, a fatal, childhood-onset disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics