Gene News and Research

Latest Gene News and Research

Brain imaging shows differences in people at risk for Alzheimer's

Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

20 Nov 2004

Overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) reduces tumor growth

Scientists have found that overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) blocks the formation of new blood vessels and thus reduces tumor growth. Therapeutics based on this finding may potentially lead to new cancer treatments.

19 Nov 2004

Researchers find mutations in a multifunctional protein cause Parkinsonism

A team of researchers at Mayo Clinic in Jacksonville, Fla. and colleagues in Canada and Germany have discovered a gene and six mutations of it that cause symptoms associated with Parkinson's disease and other neurodegenerative disorders.

18 Nov 2004

New genetic test has proven useful as a prognostic tool for ovarian cancer

The identification of a gene expression profile using microarray technology may help clinicians better determine the prognosis of patients with advanced stage ovarian cancer and may eventually help provide targeted therapies for this hard-to-treat disease, according to a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC).

18 Nov 2004

Understanding the signals that delay the spread of follicular lymphoma could provide new therapeutic targets

Scientists at the National Cancer Institute (NCI), have created a model that predicts the survival of follicular lymphoma patients based on the molecular characteristics of their tumors at diagnosis.

18 Nov 2004

70% of cases of spina bifida are preventable by folic-acid supplementation

A seminar in this week’s issue of THE LANCET discusses the causes, symptoms, and treatments relating to spina bifida, and reinforces an important public-health message for women about to become pregnant

18 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Not all congestion-producing chronic rhinosinusitis infections are the same

Rather, this problem that afflicts some 30 million Americans annually has four severity classifications that could help guide treatment today and help find better treatments in the future, says the lead author on the study published in the November issue of The Laryngoscope.

18 Nov 2004

Gene protects against environmental pollutants and pulmonary emphysema

Researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions have identified a “master gene” in mice that controls the action of 50 other genes whose products protect the lungs against environmental pollutants.

17 Nov 2004

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Remember when Grandma used to say, "don’t go out in the cold; you’ll get sick”? It turns out that she was right for a small number of people who have a condition called familial cold autoinflammatory syndrome (FCAS)

16 Nov 2004

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

What makes beer taste so darn good to men, but vile to most women?

What makes beer taste so darn good to men, but vile to most women? Some oral sensations are under genetic control and new research suggests that these influences on taste perception could help determine the risk of excess alcohol consumption.

16 Nov 2004

Novel enzyme in sperm is essential for spontaneous and independent movement

A study led by scientists at the University of North Carolina at Chapel Hill has found that a novel enzyme in sperm is essential for spontaneous and independent sperm movement as well as male fertility.

16 Nov 2004

Discovery of new compounds that may treat mucus build-up associated with cystic fibrosis

Preliminary studies show these compounds improve the flow of mucus through the respiratory tract, allowing airways to clear more quickly and efficiently.

14 Nov 2004

Research opens up new avenues to diagnosis and treat Lyme disease

Researchers at Yale School of Medicine have identified a Lyme disease receptor called TROSPA that is used by disease agents to invade ticks.

14 Nov 2004

The brain's dopamine system is key to alcoholism

Among the many genes that may contribute to an individual's susceptibility to alcoholism, those in the dopamine system are of special interest because addictive substances can activate this system.

14 Nov 2004

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

The enzyme is known as PTPRO (for “protein tyrosine phosphatase receptor-type O”). When the gene responsible for producing PTPRO is silenced, as can happen in lung cancer, for example, the amount of the enzyme drops, allowing the cells to grow when they shouldn’t.

11 Nov 2004

Gene News and Research

Latest Gene News and Research

Brain imaging shows differences in people at risk for Alzheimer's

Overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) reduces tumor growth

Researchers find mutations in a multifunctional protein cause Parkinsonism

New genetic test has proven useful as a prognostic tool for ovarian cancer

Understanding the signals that delay the spread of follicular lymphoma could provide new therapeutic targets

70% of cases of spina bifida are preventable by folic-acid supplementation

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Not all congestion-producing chronic rhinosinusitis infections are the same

Gene protects against environmental pollutants and pulmonary emphysema

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Troponin genes offer new insights to familial heart failure

What makes beer taste so darn good to men, but vile to most women?

Novel enzyme in sperm is essential for spontaneous and independent movement

Discovery of new compounds that may treat mucus build-up associated with cystic fibrosis

Research opens up new avenues to diagnosis and treat Lyme disease

The brain's dopamine system is key to alcoholism

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

Research aims to understand how genetic information translates into biological activity

Shp2 protein plays a critical role in obesity

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

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