Genetics News and Research

Latest Genetics News and Research

Largest "gene deserts" yet discovered in the human genome sequence

A detailed analysis of chromosomes 2 and 4 has detected the largest "gene deserts" known in the human genome and uncovered more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes, researchers supported by the National Human Genome Research Institute (NHGRI).

6 Apr 2005

Gene therapy shows effect in heart patients

The first double-blind, placebo-controlled randomized trial of VEGF gene injections into the heart muscle of patients with coronary artery disease with the intention of spurring growth of new blood vessels showed significant effects on heart wall motion, although blood flow was not significantly better in treated patients, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Genetic testing could bolster radiotherapy's effectiveness against cancer

Obtaining a genetic picture of how a tumor will react to the many treatment techniques available could help doctors prescribe therapies customized for individual cancer patients' needs, suggests a Purdue University research team.

5 Apr 2005

Metabolic side effects of antipsychotics are known, but rarely monitored

Psychiatrists are doing a “modest” job of monitoring for weight gain, diabetes and other metabolic problems that may result from use of the newer antipsychotics for schizophrenia, researchers say.

5 Apr 2005

Method of gene therapy accurately corrects mutations in disease-causing genes

Harnessing the strength of a natural process that repairs damage to the human genome, a researcher from UT Southwestern Medical Center has helped establish a method of gene therapy that can accurately and permanently correct mutations in disease-causing genes.

5 Apr 2005

Promising new therapy that prompts the immune system to aid in the fight against melanoma tumors

Melanoma is a particularly deadly form of skin cancer very resistant to treatment. Researchers at H. Lee Moffitt Cancer Center & Research Institute and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors.

5 Apr 2005

Genomics and proteomics to increase the efficiency of drug discovery and development

While the United Sates is still the world leader, Europe is having a good deal of success in the field of advanced genomics and proteomics research. Significant government funding together with the presence of large pharmaceutical companies has made Europe a major competitor in the efforts to deploy genomics and proteomics as vital tools in drug discovery and development.

5 Apr 2005

Pair of cancer genes found to drive both cell migration and division

Johns Hopkins researchers have found that two genes already known to control cell movement are also needed for proper cell division. They report their findings in the April issue of Developmental Cell.

5 Apr 2005

DNA repair kit announced by scientists

A study by scientists at Sangamo BioSciences, Inc. has demonstrated the use of the Company's zinc finger DNA-binding protein (ZFP) technology to achieve highly efficient, permanent correction of a disease-causing gene in primary human cells.

5 Apr 2005

Canada spends more on stem cell research

Canadian Justice Minister Irwin Cotler gave Canadian stem cell research an extra boost with the announcement of $5.3 million in annual funding.

5 Apr 2005

Alteration of steroid receptor genes creates fat burning muscle

The Salk Institute scientist who earlier discovered that enhancing the function of a single protein produced a mouse with an innate resistance to weight gain and the ability to run a mile without stopping has found new evidence that this protein and a related protein play central roles in the body's complex journey to obesity and offer a new and specific metabolic approach to the treatment of obesity related disease such as Syndrome X (insulin resistance, hyperlipidemia and atherosclerosis).

4 Apr 2005

Gene mutation protecting against malaria linked to prostate cancer incidence in African-American men

Research from the University of Cincinnati College of Medicine suggests that the 60 percent greater incidence of prostate cancer among African-American men is related to a gene mutation developed generations ago in West Africa as nature's way of providing protection from the malaria infection endemic in that part of the world.

4 Apr 2005

Natural killer cells could lead to new Hepatitis treatments

Researchers have discovered that natural killer T (NKT) cells, the immune system's sentinels, patrol the labyrinthine blood vessels of the liver for invaders or signs of tissue damage and demonstrate a dogged behavior not seen before in other T cells.

4 Apr 2005

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Scientists at New York University School of Medicine viewing the actual journey of immune cells in the liver have found that these cells travel in the liver's blood vessels with surprising speed and agility.

4 Apr 2005

Method of gene therapy that can accurately and permanently correct mutations in disease-causing genes

4 Apr 2005

Obesity may hinder body's ability to control influenza infection

Obesity apparently reduces laboratory mice’s ability to turn on elements of their immune systems needed for controlling influenza infection, a new University of North Carolina at Chapel Hill School of Medicine study shows.

4 Apr 2005

Step toward a potential treatment for Huntington's disease

Researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine have taken another step toward a potential treatment for Huntington's disease (HD). Using an approach called RNA interference (RNAi), the scientists reduced levels of the disease-causing HD protein in mice and significantly improved the movement and neurological abnormalities normally associated with the disease.

4 Apr 2005

Chronic inflammation caused by too little stomach acid leads to gastric cancer

When it comes to gastric cancer, too little stomach acid can be just as dangerous as too much, according to scientists at the University of Michigan Medical School. Both extremes create inflammatory changes in the stomach lining and a condition called chronic atrophic gastritis, which over time often leads to cancer.

4 Apr 2005

Mutations in the HFE gene directly associated with chronic joint disease

Mutations in the HFE gene, which is involved in iron regulation, seem to be directly associated with chronic joint disease (or haemophilic arthropathy) among haemophilic patients, claim a team of Portuguese scientists in the April issue of the journal Blood.

4 Apr 2005