Genetics News and Research

Latest Genetics News and Research

New technique to deliver gene therapy to soft-tissue tumors

Using new research and technology that shows bone marrow-derived mesenchymal stem cells (MSCs) will engraft at the site of a tumor and contribute to the growth of stromal fibroblasts (the healthy tissue surrounding a tumor)

2 May 2004

Once expected to die in early childhood, children born with HIV are now surviving into their teens

Once expected to die in early childhood, children born with HIV are now surviving into their teens and early adulthood thanks to research advances over the past decade. However, it's also likely these children will develop drug resistance due to sequential exposure to HIV treatments, including antiretroviral (ARV) therapies.

2 May 2004

Scientists find genetic link between prostate cancer and hereditary form of breast and ovarian cancer

A new study shows that the risk for prostate cancer is significantly elevated in men who are part of families with a hereditary form of breast and ovarian cancer. Researchers at Memorial Sloan-Kettering Cancer Center have determined that men in families carrying BRCA genetic mutations have a three- to five-fold increased risk of prostate cancer.

1 May 2004

New research could reduce risk of strokes in younger people

The study published in this month's edition of the international journal Stroke is the first to provide evidence that blood vessels elsewhere in the body, apart from the brain, in CADASIL sufferers are abnormal in over-constricting in response to the hormone Angiotensin II.

1 May 2004

Protein expression of the tumor suppressing gene could play a vital role in ovarian cancer

Protein expression of the tumor suppressing gene Rb2/p130 could play a vital role in ovarian cancer, according to a study by researchers at the Sbarro Institute for Cancer Research and Molecular Medicine in the Center for Biotechnology at Temple University

1 May 2004

Researchers profile over 6000 genes in the two primary types of normal breast cells

For several years, scientists have attempted to identify gene expression changes, using microarrays or ‘DNA chips’, in order to understand and predict breast cancer onset, progression, and clinical outcome.

1 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

Researchers discover gene responsible for neonatal diabetes

Researchers at Oxford University and the Peninsula Medical School in Exeter have located a gene responsible for around a third of cases of neonatal diabetes. Their findings are likely to lead to treatment of the condition by means of a tablet rather than injections, improving the quality of life of both patients and their parents.

30 Apr 2004

Gene therapy may delay Alzheimer progression

Results from a preliminary eight-patient study of gene therapy for Alzheimer’s disease are positive enough to justify a larger clinical trial, Mark H. Tuszynski, M.D., Ph.D., reported April 27 at the 56th Annual Meeting of the American Academy of Neurology. Dr. Tuszynski says that a larger trial is being planned at a major medical center in Chicago.

30 Apr 2004

Australian research helps to better understand asthma, hayfever, eczema and associated allergies

May 4, 2004 is World Asthma Day. Asthma, hayfever, eczema and associated allergies are among the most common chronic diseases in the developed world. It has been estimated that up to 50% of people in western societies suffer from these conditions, and in Australia alone, health care costs for asthma alone exceed $700 million each year.

29 Apr 2004

Functional genomics and proteomics may accelerate the discovery of new drugs and therapeutic molecules

Functional genomics and proteomics have been quite successful in identifying functions of potential therapeutic targets such as encoded proteins. In fact, the possibilities of identifying more than 10,000 novel target antigens in the human genome may accelerate the discovery of new drugs and therapeutic molecules.

29 Apr 2004

Scientists have discovered a genetic cause of cleft lip and palate in mice

By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.

29 Apr 2004

Time bomb in heart leads to heart failure in some congenital heart disease patients

However, surgical correction of certain forms of congenital heart disease may not fix the underlying molecular trigger that drives progressive heart failure and sudden death later in life, according to new research from the University of California, San Diego (UCSD) School of Medicine.

29 Apr 2004

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

In the study, a team of researchers led by Veridex, LLC, a Johnson & Johnson company, used gene expression profiling to identify the new marker – a 23-gene signature – which may predict disease recurrence in patients initially diagnosed with Dukes' B colon cancer.

29 Apr 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

Scientists have unraveled the behavior of one key component of bacteria

The researchers studied a mechanism of action they call the "magic spot" – an important regulator of gene expression. They describe their results in the current issue of the journal Cell.

29 Apr 2004

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Mutation of a gene involved in non-small cell lung cancer (NSCLC) increases the likelihood that the drug gefitinib (Iressa™) will show a beneficial response, researchers at the Dana-Farber Cancer Institute, the National Cancer Institute (NCI) - part of the National Institutes of Health - and two other institutions announced today in the online version of Science.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

In a paper that will be published on Thursday, April 29, 2004 in the New England Journal of Medicine, a team of scientists from Stanford University and Applied Biosystems, an Applera Corporation business, describe the identification of six genes associated with survival in diffuse large B cell lymphoma (DLBCL), the most common form of non-Hodgkin's lymphoma.

28 Apr 2004

Genetics News and Research

Latest Genetics News and Research

New technique to deliver gene therapy to soft-tissue tumors

Once expected to die in early childhood, children born with HIV are now surviving into their teens

Scientists find genetic link between prostate cancer and hereditary form of breast and ovarian cancer

New research could reduce risk of strokes in younger people

Protein expression of the tumor suppressing gene could play a vital role in ovarian cancer

Researchers profile over 6000 genes in the two primary types of normal breast cells

Developing smart drugs

Researchers discover gene responsible for neonatal diabetes

Gene therapy may delay Alzheimer progression

Australian research helps to better understand asthma, hayfever, eczema and associated allergies

Functional genomics and proteomics may accelerate the discovery of new drugs and therapeutic molecules

Scientists have discovered a genetic cause of cleft lip and palate in mice

Time bomb in heart leads to heart failure in some congenital heart disease patients

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

New technique of identifying genes may help researchers developing drugs

Scientists have unraveled the behavior of one key component of bacteria

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Lou Gehrig’s disease gene discovered

Results look promising in Alzheimer’s gene therapy trial

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

Sequencing & Genomics: Elevating Science and Healthcare eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production