Genetics News and Research

Latest Genetics News and Research

NIH project homes in on COVID racial disparities

While the disproportionate impact of COVID-19 on Black and Hispanic Americans is no secret, federal officials have launched studies of the disparity that they hope will better prepare the country for the next great epidemic.

21 Jul 2020

Drug discovery pipeline to exploit transcription factors for cancer therapy

Cancer is a leading cause of death and one of the most complex challenges to modern medicine. By employing cutting-edge technologies that precisely measure the effects of candidate targets and drugs on the fundamental process of transcription, the new start-up company QUANTRO Therapeutics strives to radically change the precision and scope of cell-based drug screening.

21 Jul 2020

Prostate tumors reactivate dormant molecular program during metastatic progression

When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute.

20 Jul 2020

Mutant zebrafish opens a window into evolutionary history of human spine

A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past.

20 Jul 2020

$Genetic markers can improve screening for osteoporotic fracture risk$

Genetic markers can improve screening for osteoporotic fracture risk

A new study shows that genetic pre-screening could reduce the number of screening tests needed to identify individuals at risk for osteoporotic fractures. Douglas P. Kiel, M.D., M.P.H., director of the Musculoskeletal Research Center in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, is an author on the report published this month in PLOS (Public Library of Science) Medicine.

20 Jul 2020

Developing a Better Understanding of Polycystic Ovary Syndrome (PCOS)

In this interview, Dr. Andrea Dunaif talks to News-Medical about their genetic analysis study which suggests there are different subtypes of PCOS.

20 Jul 2020

Researchers unravel key mechanisms behind the mysteries of aging

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

16 Jul 2020

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

16 Jul 2020

Weak immune status, and not HIV infection affects cavity prevalence in children

Recent studies indicate HIV infection heightens the risk of dental cavities - but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases.

16 Jul 2020

Researchers solve the mystery of genetic defect in horses

Warmblood fragile foal syndrome is a severe, usually fatal, genetic disease that manifests itself after birth in affected horses.

16 Jul 2020

Likelihood of SARS-CoV-2 transmission may depend on blood type of spreader and recipient

A modeling study by Dr. Peter Ellis from the University of Kent indicates that ABO incompatibility between infected patients and susceptible individuals may actually decrease the transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by 60% or more. His detailed investigation of such "ABO-interference" can be found on the medRxiv preprint server.

15 Jul 2020

Transmission of coronavirus from dogs to humans is scientifically flawed

A study published earlier this year claiming the coronavirus may have jumped from dogs to humans is scientifically flawed, offering no direct evidence to support its conclusions, according to a collaborative group of international researchers, including scientists at the University of Colorado Anschutz Medical Campus.

15 Jul 2020

Silver strands and graying hair are not signs of aging in chimpanzees

Silver strands and graying hair is a sign of aging in humans, but things aren't so simple for our closest ape relatives--the chimpanzee. A new study published today in the journal PLOS ONE by researchers at the George Washington University found graying hair is not indicative of a chimpanzee's age.

15 Jul 2020

Researchers characterize how changes in glioblastoma cells influence different drug effects

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

14 Jul 2020

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

International research collaboration to investigate the role of immune system in health

An international research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

13 Jul 2020

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

11 Jul 2020

Innovative system aims to improve predictions of survival indicators in breast cancer patients

Improving the predictions of survival indicators in breast cancer patients through artificial intelligence and probabilistic modeling tools is the goal of ModGraProDep, an innovative system presented in a study published in the journal Artificial Intelligence in Medicine.

11 Jul 2020

Researchers map non-coding, 'functional' genome in maize during early reproductive development

Growth and development of all organisms depends on coordinated regulation of gene expression in time and space, and this is largely controlled by non-coding sequences in the genome.

8 Jul 2020

Study: E. coli Nissle may also protect human cells against other pathogenic strains

Typically, there aren't a lot of positive thoughts when E. coli, generally found in animal and human intestines, is mentioned. It's been blamed for closing beaches and swimming pools and shuttering restaurants because of contamination in salad bars, meats or other food items.

8 Jul 2020

Genetics News and Research

Latest Genetics News and Research

NIH project homes in on COVID racial disparities

Drug discovery pipeline to exploit transcription factors for cancer therapy

Prostate tumors reactivate dormant molecular program during metastatic progression

Mutant zebrafish opens a window into evolutionary history of human spine

Genetic markers can improve screening for osteoporotic fracture risk

Developing a Better Understanding of Polycystic Ovary Syndrome (PCOS)

Researchers unravel key mechanisms behind the mysteries of aging

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Weak immune status, and not HIV infection affects cavity prevalence in children

Researchers solve the mystery of genetic defect in horses

Likelihood of SARS-CoV-2 transmission may depend on blood type of spreader and recipient

Transmission of coronavirus from dogs to humans is scientifically flawed

Silver strands and graying hair are not signs of aging in chimpanzees

Researchers characterize how changes in glioblastoma cells influence different drug effects

Researchers uncover new mechanism for designing antiviral drugs for dengue virus

International research collaboration to investigate the role of immune system in health

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Innovative system aims to improve predictions of survival indicators in breast cancer patients

Researchers map non-coding, 'functional' genome in maize during early reproductive development

Study: E. coli Nissle may also protect human cells against other pathogenic strains

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production