Genetics News and Research

Latest Genetics News and Research

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

Alzheimer's genetic risk studies undermined by systemic biases

Recent research in Nature Genetics reveals pervasive biases in GWAX studies using parental history of Alzheimer’s, highlighting potential misdirection in genetic associations and disease risk predictions. A novel GSUB method identifies false signals stemming from confounding factors like survival bias and socioeconomic status.

4 Dec 2024

ACMG sets new lifelong guidelines for managing phenylalanine hydroxylase deficiency

Updated evidence-based clinical guidelines for phenylalanine hydroxylase deficiency diagnosis and management.

4 Dec 2024

Immune cells play a key role in movement control and metabolic balance

Immune cells have a surprising and critical role in controlling movement and bridging neural activity with metabolic demands, concludes a groundbreaking study published in Nature by researchers at the University of Copenhagen and Imperial College London.

4 Dec 2024

Common farming pesticides linked to rheumatoid arthritis

Exposure to specific pesticides is linked to increased rheumatoid arthritis risk, with notable dose-response trends for malathion and carbofuran among older licensed applicators in the Agricultural Health Study.

4 Dec 2024

Fructose consumption linked to accelerated tumor growth in cancer models

Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.

4 Dec 2024

COPD patients' perspectives should guide development of new therapies

The perspectives and priorities of people living with chronic obstructive pulmonary disease (COPD) should be integrated into the development process of new therapies for COPD, according to a new commentary.

4 Dec 2024

Professor Peter Falkai suggests promising new directions in schizophrenia treatment

In a comprehensive Genomic Press Interview, distinguished psychiatrist Professor Peter Falkai suggests promising new directions in schizophrenia treatment through his groundbreaking research on brain plasticity and myelin regeneration.

4 Dec 2024

Novel single-cell genomics analysis approach provides direct insights into cell cycle and proliferation

By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies key clones in cancer progression.

4 Dec 2024

Disrupted sleep-wake rhythms linked to liver disease progression

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles. MASLD (formerly known as non-alcoholic fatty liver disease) is already the most common liver disorder: it affects 30% of adults and between 7% and 14% of children and adolescents, and this prevalence is predicted to rise to more than 55% of adults by 2040.

4 Dec 2024

New algorithm identifies tumor cells driving aggressive cancer growth

The first computer algorithm capable of identifying which tumor cells are driving aggressive cancer growth has been developed by Cancer Research UK-funded scientists from UCL and The Francis Crick Institute.

3 Dec 2024

Study finds T cell exhaustion in chronic fatigue syndrome patients

Chronic fatigue syndrome creates conditions where pathogen-killing immune T cells become exhausted, according to a new Cornell University study.

3 Dec 2024

Scientists aim to identify the most effective TBS protocols for treating schizophrenia

Schizophrenia, which is characterized by positive symptoms (e.g., hallucinations and delusions), negative symptoms (diminished emotional expressions or avolition), and cognitive impairments (attention deficits and poor learning skills), is a serious mental health condition that affects how individuals think, behave, and perceive the world.

3 Dec 2024

Disrupted sleep patterns identified in patients with metabolic dysfunction-associated steatotic liver disease

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles.

2 Dec 2024

New algorithm identifies cells responsible for aggressive tumor growth

Cancer Research UK-funded scientists have unveiled the first computational algorithm capable of identifying which cell populations within a tumor drive aggressive growth.

2 Dec 2024

Researchers develop organoid mimicking human fetal pancreas

Researchers from the Organoid group (previously Clevers group) at the Hubrecht Institute have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development.

2 Dec 2024

Study reveals varied risks of hormone treatments for menopausal symptoms

Researchers at Uppsala University have analyzed the effects of seven different hormone treatments for menopausal symptoms on the risk of blood clots, stroke and heart attack.

28 Nov 2024

Research paves the way for genetic control of disease-spreading ticks

Research collaboration by the Texas A&M Department of Entomology and the U.S. Department of Agriculture, USDA, creates potential for genetic tools to control disease-spreading ticks.

27 Nov 2024

TRiC mutations found to cause developmental brain malformations in children

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

27 Nov 2024

Research shows "Alzheimer's in a dish" model can accelerate drug discovery

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks.

27 Nov 2024