Genetics News and Research

Latest Genetics News and Research

Genetically caused deafness may be reversible by compensating for a missing protein

Emory University researchers have found that in mice, increasing the amount of the protein connexin26 in the ear's cochlea compensates for an absence of another protein, connexin30.

26 Feb 2007

Irregular heartbeat linked to genetic mutation

Every day for 10 years, a seemingly heart-healthy 53-year-old woman experienced rapid and irregular heartbeats. She had no personal or family history of hypertension or hyperthyroidism. She did not suffer from myocardial or coronary artery disease, or any abnormalities of the heart as best doctors and medical science could determine.

25 Feb 2007

microRNA directly regulates a gene implicated in human cancers

MicroRNAs are tiny snippets of RNA that can repress activity of a gene by targeting the gene's messenger RNA (which copies DNA information and starts the process of protein production).

22 Feb 2007

Research defines the cancer role for protein Gab-2

A protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease's deadliest stage, a study from Burnham Institute for Medical Research has found.

22 Feb 2007

microRNAs undergo molecular editing with significant physiological consequences

Tiny molecules called microRNAs, only 19 to 21 nucleotides in length, are able to effectively silence sometimes large sets of genes. They do this by specifically binding to and neutralizing another form of RNA called messenger RNA, responsible for conveying the information from genes to the cellular machinery that uses that information to create proteins, the building blocks of the body.

22 Feb 2007

Abnormalities in eye movements and attention define risk for schizophrenia

A Binghamton University researcher has established a new framework to help determine whether individuals might be at risk for schizophrenia.

22 Feb 2007

Women in the UK to trade eggs for IVF treatment

According to the fertility regulator in the UK women there will soon be able to donate their eggs for medical research.

21 Feb 2007

Experimental vector vaccine reduces stillbirths from cytomegalovirus

Researchers funded by the National Institutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV) - a common virus that can also cause mental retardation and hearing loss in newborn children who were infected in early fetal life.

21 Feb 2007

Reduced brain growth in alcoholics with family drinking history

The brains of alcohol-dependent individuals are affected not only by their own heavy drinking, but also by genetic or environmental factors associated with their parents- drinking, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

21 Feb 2007

Swedish brain researchers gain access to unique IBM supercomputer

Approximately 127 million people in Europe are suffering from some kind of brain disease or injury. With the long term goal to improve diagnostics and find new therapies in their sights, the Stockholm Brain Institute (SBI) and IBM have embarked on a partnership that gives Swedish brain researchers access to a unique supercomputer.

21 Feb 2007

Scientists find new genes linked to Lou Gehrig's disease

In the first genome-wide search for the genetic roots of the most common form of amyotrophic lateral sclerosis (ALS), Johns Hopkins scientists have newly identified 34 unique variations in the human genetic code among 276 unrelated subjects with ALS.

21 Feb 2007

Genentech updates on Cabilly patent peexamination

Genentech, Inc. has announced today that the U.S. Patent and Trademark Office issued a final Office action in its reexamination of the Cabilly, et al. U.S. Patent No. 6,331,415 ('415 patent) and rejected the patentability of the claims of the '415 patent.

21 Feb 2007

Low-cost Parkinson's disease diagnostic test a world first

Scientists at Melbourne's Howard Florey Institute have developed a cost-effective diagnostic test for Parkinson's disease (PD), which will also assist researchers to understand the genetic basis of PD and to undertake large-scale studies to identify the genes that cause this debilitating condition.

21 Feb 2007

Anorexia nervosa may be genetic

A researcher in the United States says a ten year study into the eating disorder anorexia nervosa suggests that sufferers may have a genetic predisposition for it.

21 Feb 2007

New test identifies suitable lymphoma patients likely to respond to new therapy

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered a genetic signature identifying cases of lymphoma that are uniquely susceptible to a newly developed molecular targeted therapy. As a result, physicians organizing clinical trials of the new therapy will be able to enroll patients who'll be most likely to benefit from it.

20 Feb 2007

Cancer cells 100 times more likely to genetically mutate

When cells become cancerous, they also become 100 times more likely to genetically mutate than regular cells, researchers have found. The findings may explain why cells in a tumor have so many genetic mutations, but could also be bad news for cancer treatments that target a particular gene controlling cancer malignancy.

20 Feb 2007

Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia

Reviewing published reports, Ferkol and Margaret Leigh, M.D., professor of pediatrics at the University of North Carolina at Chapel Hill (UNC), found that neonatal respiratory distress was a common clinical symptom of PCD, a chronic airway disease that affects about 1 in 15,000 children.

20 Feb 2007

Transmission of drug-resistant tuberculosis among treated patients in Shanghai

A newly released study suggests that the majority of cases of drug-resistant tuberculosis (TB) among patients undergoing treatment for the disease may be due to new infections, not acquired resistance.

20 Feb 2007

Researchers discover markers that identify breast cancer subtypes resistant to Herceptin

Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor.

20 Feb 2007

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein.

20 Feb 2007