Genetics News and Research

Latest Genetics News and Research

Hap1 protein could lead to future drug targets for eating disorders

Researchers have discovered how the protein Hap1, which is abundant in the brain's hypothalamus, serves as the link between circulating insulin in the blood and the neural circuitry that controls feeding behavior in mice.

16 Apr 2006

Nimesulide fights breast cancer by targeting key enzyme

A pain-killing medication appears to halt the production of an enzyme that is key to a common form of breast cancer, a new study using tissue cultures suggests.

16 Apr 2006

First gene therapy human trial in the United States for a form of muscular dystrophy under way

The clinical trial for Duchenne muscular dystrophy (DMD) tests the safety and effectiveness of a therapy that was developed over two decades by scientists at the University of North Carolina Chapel Hill's School of Medicine and the University of Pittsburgh.

16 Apr 2006

Doses of DNA-gene-coated gold particles protect against harmful protein implicated in Alzheimer's disease

Doses of DNA-gene-coated gold particles protect mice against a protein implicated in Alzheimer's disease, researchers at UT Southwestern Medical Center have found.

16 Apr 2006

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.

16 Apr 2006

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes are caused by enzyme deficiencies and typically have crippling, even fatal, consequences starting at very early ages.

13 Apr 2006

Researchers find genetic "signature" that accurately identifies colon cancer

Researchers at Jefferson Medical College in Philadelphia have uncovered a genetic "signature" that accurately identifies colon cancer--a key, they hope, to better understand how the cancer develops.

13 Apr 2006

Active ingredient in soy may explain why Asians have lower rates of obesity and cancer

A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.

13 Apr 2006

Environmental scientists identify new culprits in the cancer equation

In the granite-rich region of Western North Carolina, taking a daily shower could pose a risk of developing lung cancer. So could working from home every day. That's because granite emits a carcinogenic gas, radon.

13 Apr 2006

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

A study led by researchers from the Howard Hughes Medical Institute has found that dasatinib provides significant benefit in chronic myeloid leukemia (CML) patients resistant to Gleevec. (imatinib), according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

11 Apr 2006

Researchers identify the role of a protein in hemoglobin gene silencing

Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.

11 Apr 2006

New model of p53 regulation has important implications for the development of anticancer drugs

Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about how a powerful tumor suppressor called p53 is controlled in cells. Their new model of p53 regulation has important implications for the development of anticancer drugs.

11 Apr 2006

Research explains why recipients of growth hormone therapy may develop colon polyps

The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer - but medical researchers have debated the extent of a cancer risk.

11 Apr 2006

Gene variant doubles risk for obsessive-compulsive disorder

Scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) have identified a previously unknown gene variant that doubles an individual's risk for obsessive-compulsive disorder (OCD).

11 Apr 2006

Scientists reconstruct Darwinian evolution to explain 'irreducible complexity'

Using new techniques for resurrecting ancient genes, scientists have for the first time reconstructed the Darwinian evolution of an apparently "irreducibly complex" molecular system.

11 Apr 2006

Losartan can prevent progression of Marfan syndrome

A commonly prescribed blood pressure medication may provide the first ray of hope in preventing potentially deadly complications of Marfan syndrome, a genetic disease that weakens the structural meshwork of blood vessels.

11 Apr 2006

Colorimetric screening detects DNA, small molecules and proteins

Using the unusual color properties of gold at the nanoscale, scientists at Northwestern University have developed a "litmus test" for DNA and small molecule binding that eventually could be used by pharmaceutical companies to rapidly identify promising candidates for new anti-cancer drugs.

11 Apr 2006

Researchers identify new disorder called cortical dysplasia-focal epilepsy syndrome

Researchers from the Translational Genomics Research Institute (TGen) and the Clinic for Special Children (CSC) in Strasburg, PA, have described a new childhood-onset disorder characterized by severe epilepsy and autistic traits, and identified its genetic basis.

11 Apr 2006

Biodegradable drug containing nano-particles effective in killing human breast tumors

Research studies, based at the University of Pennsylvania, demonstrate that biodegradable nano-particles containing two potent cancer-fighting drugs are effective in killing human breast tumors.

11 Apr 2006

Lack of response to herceptin may be reversed with PI3K inhibiting agents

Breast cancer patients with HER2-positive tumors who don't respond to Herceptin (trastuzumab) may benefit from cocktail therapy that includes Herceptin along with one or more PI3K inhibiting agents, say researchers at the University of Texas M. D. Anderson Cancer Center.

11 Apr 2006

Genetics News and Research

Latest Genetics News and Research

Hap1 protein could lead to future drug targets for eating disorders

Nimesulide fights breast cancer by targeting key enzyme

First gene therapy human trial in the United States for a form of muscular dystrophy under way

Doses of DNA-gene-coated gold particles protect against harmful protein implicated in Alzheimer's disease

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Researchers find genetic "signature" that accurately identifies colon cancer

Active ingredient in soy may explain why Asians have lower rates of obesity and cancer

Environmental scientists identify new culprits in the cancer equation

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

Researchers identify the role of a protein in hemoglobin gene silencing

New model of p53 regulation has important implications for the development of anticancer drugs

Research explains why recipients of growth hormone therapy may develop colon polyps

Gene variant doubles risk for obsessive-compulsive disorder

Scientists reconstruct Darwinian evolution to explain 'irreducible complexity'

Losartan can prevent progression of Marfan syndrome

Colorimetric screening detects DNA, small molecules and proteins

Researchers identify new disorder called cortical dysplasia-focal epilepsy syndrome

Biodegradable drug containing nano-particles effective in killing human breast tumors

Lack of response to herceptin may be reversed with PI3K inhibiting agents

Sequencing & Genomics: Elevating Science and Healthcare eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production