Genetics News and Research

Latest Genetics News and Research

Variation in IGF1 gene may play a role in prostate cancer risk

Two variations in the gene for insulin-like growth factor I (IGF-1) are linked to an increased risk of prostate cancer, according to research performed by scientists from the Keck School of Medicine of the University of Southern California, the Broad Institute of Harvard and MIT, and the University of Hawaii.

18 Jan 2006

Alzheimer's may be triggered by neuron division

A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.

18 Jan 2006

Genetic risk factor for West Nile virus infection identified

People who lack a cell surface protein called CCR5 are highly resistant to infection by HIV but may be at increased risk of developing West Nile virus (WNV) illness when exposed to the mosquito-borne virus, report researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

18 Jan 2006

X-linked agammaglobulinemia

Individuals who have a rare genetic immune system disorder that prevents them from making antibodies nevertheless appear to be moderately healthy and lead productive lives, according to results of a study by investigators at St. Jude Children's Research Hospital.

18 Jan 2006

Cloned stem cells are perfectly normal

Scientists generally agree that all cloned animals are biologically flawed. But they don't agree about what that means for stem cells derived from cloned embryos, the basis for therapeutic cloning.

18 Jan 2006

Missing protein C/EBPb may be cause of infertility

The absence of a key protein may lead to infertility. Researchers at the University of Illinois at Urbana-Champaign report that experiments involving mice -- to be detailed in the Proceedings of the National Academy of Sciences -- indicate that the transcription factor protein C/EBPb must be present in the uterus for pregnancy to occur.

18 Jan 2006

Single gene may hold key to schizophrenia

By deleting a single gene in a small portion of the brains of mice, researchers at UT Southwestern Medical Center found that the animals were affected in a way resembling schizophrenia in humans.

18 Jan 2006

Genetic cause of autism

The researchers at the U School of Medicine made the finding by tracing variations in the DNA of an extended Utah family that has a high occurrence of the disorder and whose members are descended from one couple.

18 Jan 2006

Identification of bipolar risk gene

A collaboration, led by scientists at the Garvan Institute of Medical Research and the University of New South Wales (UNSW) in Sydney, has discovered the first risk gene specifically for bipolar disorder, also known as manic-depressive illness. This means that people who have a particular form of this gene are twice as likely to develop the disease.

16 Jan 2006

Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease.

16 Jan 2006

Genome-wide prediction of mammalian enhancers for control of gene expression

Molecular biologists, developmental biologists and computer scientists at the Universtity of Helsinki, Finland, came together to advance towards cracking the code for how gene expression is controlled. The results of this work are published in Cell, in January 2006.

16 Jan 2006

Physiogenomic resources for rat models of heart, lung and blood disorders

Every year, heart disease claims an estimated 7 million lives, according to the World Health Organization. Scientists have struggled to pinpoint the precise genes behind this complex disease. Now, however, they have a new research ally: the designer rat.

16 Jan 2006

Target identified for therapeutic drugs to fight adult brain cancer

A research team at UT Southwestern Medical Center has discovered a cell-signaling mechanism instrumental in the most common brain cancer in adults.

16 Jan 2006

Identification of gene in childhood kidney disease

An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS). Children with MKS have central nervous system deformities as well as abnormal cysts in their kidneys, and usually die shortly after birth.

16 Jan 2006

Diabetes gene found in 40% of population

Researchers in Iceland say they have identified a single genetic change which could predispose close to 40 percent of the population to type-2 diabetes.

16 Jan 2006

Sickle cell corrected with gene copy

Scientists in the U.S. say they have found a way to use embryonic stem cells to correct the mutation that causes sickle cell disease in mice.

16 Jan 2006

DinB DNA polymerase is a key player in DNA repair

A quarter century after they discovered it, researchers have identified the job of one of the most common DNA-damage response proteins. The enzyme has puzzled scientists because it is present in nearly every organism, which suggests that it is crucial to life, and yet, in laboratory experiments, its function has remained a mystery.

11 Jan 2006

St. Jude projects 90 percent cure rate for acute lymphoblastic leukemia

The cure rate for the once almost universally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital.

11 Jan 2006

Protein finding could lead to new topical treatment for inflammatory diseases

A protein that undesirably shields a skin poxvirus from the immune system may become the key ingredient in a new topical treatment for inflammatory diseases, say medical researchers at the University of Illinois at Urbana-Champaign.

11 Jan 2006

New disability website launched

Med Services Europe has announced the launch of " New Disability", a website dedicated to products for the disabled community. According to Dr. Gene Emmer, President of Med Services Europe, the goal of New Disability is to be a platform to advance the commercialization of assistive technology.

11 Jan 2006