Genetics News and Research

Latest Genetics News and Research

Comprehensive analysis of DNA barcodes

With species around the world disappearing faster than biologists can identify them, many scientists pinned their hopes on DNA barcoding, a recently proposed strategy that treats a short fragment of DNA as a sort of universal product code to identify species.

30 Nov 2005

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Most people with a rare type of dementia called primary progressive aphasia (PPA) have a specific combination of prion gene variants, a new study shows.

28 Nov 2005

Chronic stress induces rapid occlusion of angioplasty

Chronic stress can induce rapid blocking of arteries after a balloon angioplasty procedure, according to research performed in animal studies at Georgetown University Medical Center. Blocked coronary arteries after angioplasty affect 41 percent of patients who undergo the procedure and can lead to death.

28 Nov 2005

Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005

Master switch for blood cell development detected

Blood cells develop from blood stem cells in the bone marrow. Their development is regulated by roughly 20 gene regulators or transcription factors.

28 Nov 2005

Patient-specific stem cell lines - now a real possibility

Immune rejection problems could affect any one of us. This unique research shows that producing individual patient cell lines for our own future needs is now something we might all want to consider.

28 Nov 2005

Study links low level of response (LR) to alcohol to an area on chromosome 10

How a person "feels" the effects of alcohol is, in part, genetically influenced and relates to their risk for developing alcoholism.

28 Nov 2005

GRK5's role in restenosis

Researchers at Jefferson Medical College have begun to clarify the role of a protein - and potential drug target - in the process by which arteries re-clog after treatment.

28 Nov 2005

GRK2 protein - potential drug target for heart failure

A protein that plays an important regulatory role in heart failure in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have found. The protein, GRK2, is a potential drug target for heart failure.

28 Nov 2005

Analysis of Fcg Receptor haplotypes in rheumatoid arthritis

People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.

28 Nov 2005

Loss of genes on chromosome 1 or 11 raises the risk of death from the children's cancer neuroblastoma

A new study reports that a loss of genes on chromosome 1 or chromosome 11 raises the risk of death from the children's cancer neuroblastoma, even when other indicators seem to point to a lower-risk form of the disease.

28 Nov 2005

Genetic influences behind Dupuytren's disease or contracture

A crippling condition that can result in sufferers losing their fingers is to be investigated by scientists in one of the most detailed studies into the genetic causes of the disease ever carried out.

From The University of Manchester 26 Nov 2005

New door opens for anti-aging research in humans

A counterintuitive experiment has resulted in one of the longest recorded life-span extensions in any organism and opened a new door for anti-aging research in humans.

26 Nov 2005

Thrombospondin (TSP-1) can cause kidney failure when normal blood flow is disrupted

Scientists led by a University of Cincinnati (UC) kidney expert have found that a naturally occurring protein that normally fights cancer cells can also cause severe kidney failure when normal blood flow is disrupted.

26 Nov 2005

Researchers identify genes affected by Methotrexate (MTX)

A Queen's University study of fruit flies that may revolutionize the way birth defects are studied has identified the genes affected by a widely-prescribed drug known to cause birth defects.

26 Nov 2005

High blood pressure research advances efforts to tailor drugs to individual patients

Having high blood pressure and a particular genetic alteration dramatically increases the risk of heart attack, stroke or death, and may explain why some hypertensive patients fare worse than others - even if they take the same medication, University of Florida researchers announced.

26 Nov 2005