Heart Disease News and Research

Latest Heart Disease News and Research

Researchers develop tools for objective pain measurement in the operating room

The degree to which a surgical patient's subconscious processing of pain, or "nociception," is properly managed by their anesthesiologist will directly affect the degree of post-operative drug side effects they'll experience and the need for further pain management they'll require.

23 Sep 2024

New defibrillation strategy could enhance survival rates in cardiac arrest

Joshua Lupton, M.D., has no memory of his own cardiac arrest in 2016. He only knows that first responders resuscitated his heart with a shock from a defibrillator, ultimately leading to his complete recovery and putting him among fewer than one in 10 people nationwide who survive cardiac arrest outside of a hospital.

23 Sep 2024

Enhanced TnpB protein offers new possibilities for gene editing

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissor" but is much smaller and thus easier to transport into cells.

23 Sep 2024

Study uncovers novel genetic variant associated with intellectual disability

Researchers at the Icahn School of Medicine at Mount Sinai have published a pivotal study in Nature Genetics (DOI: 10.1038/s41588-024-01917-1) that sheds light on a novel genetic variant associated with intellectual capacities and educational outcomes.

23 Sep 2024

Chemotherapy linked to increased cardiovascular risks in older cancer survivors

A study based on clinical trial data found higher risks of stroke, heart attack, and hospital admission for heart failure in older cancer survivors.

23 Sep 2024

Research reveals disparities in diabetes drug efficacy for Black populations

New research analyzing the effects of two drugs used to treat type 2 diabetes indicates a consistent lack of cardiovascular and renal benefits in Black populations.

23 Sep 2024

Triptans better at relieving migraine pain than recently marketed and more expensive drugs

A meta-analysis reveals triptans as the most effective acute migraine treatments, highlighting the need for their inclusion in the WHO Essential Medicines List.

23 Sep 2024

Living in food deserts during early childhood raises long-term obesity risk

Children living in low-income areas with limited food access during early childhood are at greater risk for higher BMI and obesity by age 15. The strongest effects are seen when food insecurity is experienced during pregnancy and early childhood.

22 Sep 2024

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of developing type 2 diabetes, liver and heart disease as adults.

20 Sep 2024

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Researchers examine how different dietary components affect the gut microbiome and development of non-communicable diseases.

20 Sep 2024

New blood test identifies obesity-related health risks in children

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

20 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

Study highlights disparities in stroke burden across regions

Although stroke is highly preventable and treatable, there has been a rapid rise in the global stroke burden between 1990 and 2021, due to both population growth and the rise of aging populations worldwide, as well as a substantial increase in people's exposure to environmental and behavioral risk factors.

19 Sep 2024

Cancer drug shows promise for treating rare bleeding disorder

A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic and supported by the National Institutes of Health, was stopped early because of these successful findings, and has been published in the New England Journal of Medicine.

19 Sep 2024

Study highlights the importance of placental evaluation in pregnancy outcomes

In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention.

19 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

New machine learning approach boosts precision of cardiovascular risk assessments

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.

18 Sep 2024

Electrolyte abnormalities in eating disorders associated with higher risk of death from any cause

A new study published in The Lancet Psychiatry found that 32% of individuals with an eating disorder had abnormal electrolyte levels, which were associated with a higher risk of death from any cause.

18 Sep 2024

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide.

18 Sep 2024

Updated Nutri-Score system reveals stronger links between poor diet and cardiovascular disease risk

A large European study finds that consuming foods with lower nutritional quality, as graded by the updated Nutri-Score, increases the risk of cardiovascular diseases, particularly stroke and heart attack.

18 Sep 2024