Immunology News and Research

Latest Immunology News and Research

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Clinton Mathias, associate professor of nutritional sciences in the College of Agriculture, Health and Natural Resources (CAHNR), has discovered a potential new treatment for allergic reactions.

7 Jun 2024

‘Artificial lymph node’ shows potential to treat cancer

Johns Hopkins Medicine scientists say they have developed an artificial lymph node with the potential to treat cancer, according to a new study in mice and human cells.

6 Jun 2024

Developing pre-symptomatic diagnostic tools for Alzheimer's disease using long-read RNA sequencing

Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer's disease.

6 Jun 2024

Common anti-inflammatory drug could combat deadly gut fungus, study finds

A team of UC Davis Health researchers discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the nasty fungus Candida albicans in the gut.

4 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.

4 Jun 2024

New computational method developed for linking DNA marks to gene activity

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

New strategy targets rare B cells for effective HIV vaccine development

Germline-targeting epitope scaffold nanoparticles elicit rare broadly neutralizing antibody (bnAb) precursors against human immunodeficiency virus (HIV).

3 Jun 2024

Scientists identify genetic cause of rare, life-threatening immunodeficiency disorders in children

Scientists have pinpointed genetic changes that can leave children born with little to no immune defence against infection.

3 Jun 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells.

30 May 2024

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions.

29 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

New point-of-care test revolutionizes toxoplasmosis screening

An inexpensive, accurate test that detects infections with the parasite Toxoplasma gondii can provide results within 30 minutes from a finger-prick in a doctor's office or within an hour from a small blood sample tested in a local medical laboratory.

28 May 2024

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

28 May 2024

Heart failure triggers multimorbidity by altering stem cells, study reveals

Researchers identified that heart failure (HF) promotes multimorbidity by altering hematopoietic stem cells (HSCs) to produce pro-inflammatory macrophages, increasing vulnerability in multiple organs. The study highlights the role of suppressed TGF-β signaling in these alterations, contributing to chronic inflammation and subsequent health issues.

28 May 2024

Immunology News and Research

Latest Immunology News and Research

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

‘Artificial lymph node’ shows potential to treat cancer

Developing pre-symptomatic diagnostic tools for Alzheimer's disease using long-read RNA sequencing

Common anti-inflammatory drug could combat deadly gut fungus, study finds

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

New computational method developed for linking DNA marks to gene activity

New strategy targets rare B cells for effective HIV vaccine development

Scientists identify genetic cause of rare, life-threatening immunodeficiency disorders in children

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

How tight binding between immune cells dictates T cell cancer-fighting ability

Existing drug alleviates symptoms of a rare genetic syndrome

Statins may block an inflammation pathway involved in the development of cancer

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

New point-of-care test revolutionizes toxoplasmosis screening

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

Heart failure triggers multimorbidity by altering stem cells, study reveals

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