Immunology News and Research

Latest Immunology News and Research

$Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer$

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Servier and Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), jointly announced today clinical data from the pivotal Phase III TAS-102 Gastric Study (TAGS) evaluating LONSURF® (trifluridine/tipiracil, TAS-102) versus placebo and best supportive care in patients with heavily pre-treated metastatic gastric cancer who have progressed or are intolerant to previous lines of therapy.

22 Oct 2018

Scientists receive $5.1 million grant to develop stem cell-based therapy for blinding retinal conditions

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Stein Eye Institute have been awarded a $5.1 million grant from the California Institute for Regenerative Medicine to advance the development of a novel therapy for blinding retinal conditions.

19 Oct 2018

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

Researchers at La Jolla Institute for Immunology and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute's Cancer Moonshot initiative.

19 Oct 2018

New approach to understanding cancers will accelerate development of better treatments

A new innovation in cancer research will enable scientists to understand the complex causes of the disease with unprecedented speed and sophistication. This will accelerate the development of new and better treatments, and it will help researchers find ways around roadblocks that now stand in their path.

19 Oct 2018

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

A new study describes the mechanistic relationship between the cytokine interleukin-1β, (IL-1β) and obesity, showing that when IL-1β levels are increased in obesity, IL-1 receptor signaling activates multiple pathways leading to colon cancer.

18 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

New findings reveal potential cellular players in tumor microenvironment

New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy.

16 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Potential 'early warning markers' for sepsis discovered

A multi-site research collaboration supported by a Technology Strategy Board Grant has shown that immune response signatures could be used as an early warning test for the serious condition sepsis in patients attending emergency departments with suspected infection.

15 Oct 2018

MDI Biological Laboratory receives $1.2 million SEPA grant to promote data literacy

The MDI Biological Laboratory will take a national lead in teaching data literacy to students and teachers though a five-year, $1.2 million SEPA grant from the National Institute of General Medical Sciences, an institute of the National Institutes of Health.

15 Oct 2018

First-of-its-kind study to test a personalized vaccine in cancer patient

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic.

15 Oct 2018

Study unravels how cancer stem cells use normal genes in abnormal ways

CDK1 is a "normal" protein - its presence drives cells through the cycle of replication. And MHC Class I molecules are "normal" as well - they present bits of proteins on the surfaces of cells for examination by the immune system.

15 Oct 2018

Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

Rapid inactivation of MRSA superbugs using a simple LED array

Purdue University researchers are testing whether a light-active version of heme, the molecule responsible for transporting oxygen in blood circulation, may help people infected with MRSA.

12 Oct 2018

Scientists find new way to help asthmatics breathe more easily

Around the globe, an estimated 235 million people suffer from asthma. Most people are able to manage their symptoms and live healthy, active lives. However, for some, current treatments are not effective. Managing symptoms can be difficult because triggers are lurking everywhere.

12 Oct 2018

Ritual for orthodox Jewish men may offer cardiovascular health benefits, study suggests

A pilot study led by researchers at the University of Cincinnati College of Medicine suggests Jewish men who practice wearing tefillin, which involves the tight wrapping of an arm with leather banding as part of daily prayer, may receive cardiovascular health benefits.

11 Oct 2018

Computational model helps predict immune response in patients undergoing heart surgery

A research team led by Peter Sloot, professor of Complex Adaptive Systems at the UvA, has managed to pinpoint the mechanisms behind the immune response triggered in patients undergoing open heart surgery.

11 Oct 2018

New vaccine shows effective protection in animal models of Lassa fever

Lassa fever belongs to the same class of hemorrhagic fevers as Ebola. Like Ebola, it has been a major health threat in Western Africa, infecting 100,000-300,000 people and killing 5,000 per year.

11 Oct 2018

Otago scientists make a breakthrough in monkey malaria research

A breakthrough in monkey malaria research by University of Otago scientists encouraged the Bill & Melinda Gates Foundation to fund a special meeting in Dunedin recently.

11 Oct 2018

Study sheds light on lupus's autoimmune origins in precursor cells

In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been unclear, but recent research from Emory University School of Medicine sheds light on a missing link.

11 Oct 2018

Immunology News and Research

Latest Immunology News and Research

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Scientists receive $5.1 million grant to develop stem cell-based therapy for blinding retinal conditions

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

New approach to understanding cancers will accelerate development of better treatments

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

New findings reveal potential cellular players in tumor microenvironment

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Potential 'early warning markers' for sepsis discovered

MDI Biological Laboratory receives $1.2 million SEPA grant to promote data literacy

First-of-its-kind study to test a personalized vaccine in cancer patient

Study unravels how cancer stem cells use normal genes in abnormal ways

Research shows basophils are key players in lung development

Rapid inactivation of MRSA superbugs using a simple LED array

Scientists find new way to help asthmatics breathe more easily

Ritual for orthodox Jewish men may offer cardiovascular health benefits, study suggests

Computational model helps predict immune response in patients undergoing heart surgery

New vaccine shows effective protection in animal models of Lassa fever

Otago scientists make a breakthrough in monkey malaria research

Study sheds light on lupus's autoimmune origins in precursor cells

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