Immunology News and Research

Latest Immunology News and Research

Study reveals how B cells safeguard high-affinity antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

19 Mar 2025

Research findings solve the paradox of how the immune system balances speed and precision

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check.

19 Mar 2025

Testing a novel approach to restore normal heart function in Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1 (DM1) is the most common adult-onset form of muscular dystrophy and a condition that severely affects multiple organs including skeletal muscle, heart, brain and the gastrointestinal tract.

18 Mar 2025

Coalition of experts reaffirms vaccines as essential for public health

In response to growing concerns over vaccine misinformation, declining public trust in science, and recent outbreaks of preventable diseases, a coalition of 34 scientific and medical organizations, led by the American Association of Immunologists (AAI) and the American College of Physicians (ACP), has issued a unified statement emphasizing the critical role of vaccinations in public health.

18 Mar 2025

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

Mitochondria may hold key to reducing inflammaging in aging cells

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

14 Mar 2025

NIH researchers define topical steroid withdrawal diagnostic criteria

Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in the body.

14 Mar 2025

COVID-19 discovery could open the door to new treatments for chronic lung diseases

University of Virginia School of Medicine scientists have discovered how severe COVID-19 can destroy immune cells' ability to repair the lungs, helping explain the lingering effects of long COVID.

13 Mar 2025

IgE antibodies show promise in targeting HER2 cancers resistant to other therapies

Antibody treatment which activates the patient's own immune system against cancer, known as immunotherapy, is increasingly being investigated as an alternative for chemotherapy and radiotherapy.

12 Mar 2025

Nanogels can improve antibiotic delivery for urinary tract infections

Researchers from the University of Colorado Anschutz Medical Campus studied a new method to deliver antibiotics, specifically gentamicin, directly into the bladder tissue to better treat UTIs.

12 Mar 2025

Researchers identify cause of post-COVID inflammatory shock in children

MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening.

12 Mar 2025

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, and serological analyses.

From Sino Biological Inc. 12 Mar 2025

New malaria control strategy targets protein system in mosquitoes

A molecular quality-control system in Anopheles mosquitoes-the species responsible for most of the world's malaria cases-is a promising target for future malaria-control strategies, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Mar 2025

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

10 Mar 2025

Herpes infection through the nose can lead to anxiety, motor impairment and cognitive deficits

Herpes simplex virus-1 (HSV-1) is commonly known for causing blisters and sores. But in some cases, the virus can migrate to the eye or nervous system, causing severe, chronic symptoms.

10 Mar 2025

Scientists discover key molecular switch for blood stem cell regeneration

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators.

10 Mar 2025

Study reveals genes critical for tuberculosis survival during transmission

Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person's lungs to another person's during coughing, sneezing or talking, according to researchers from Weill Cornell Medicine and the Massachusetts Institute of Technology.

10 Mar 2025

Vanderbilt researchers aim to use AI to develop antibody therapies for any target

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

8 Mar 2025

Study links ITSN1 gene variants to increased Parkinson's disease risk

A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly 2% of adults older than 65 years.

7 Mar 2025

Immunology News and Research

Latest Immunology News and Research

Study reveals how B cells safeguard high-affinity antibodies

Research findings solve the paradox of how the immune system balances speed and precision

Testing a novel approach to restore normal heart function in Myotonic Dystrophy Type 1

Coalition of experts reaffirms vaccines as essential for public health

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

Mitochondria may hold key to reducing inflammaging in aging cells

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

NIH researchers define topical steroid withdrawal diagnostic criteria

COVID-19 discovery could open the door to new treatments for chronic lung diseases

IgE antibodies show promise in targeting HER2 cancers resistant to other therapies

Nanogels can improve antibiotic delivery for urinary tract infections

Researchers identify cause of post-COVID inflammatory shock in children

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

New malaria control strategy targets protein system in mosquitoes

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

Herpes infection through the nose can lead to anxiety, motor impairment and cognitive deficits

Scientists discover key molecular switch for blood stem cell regeneration

Study reveals genes critical for tuberculosis survival during transmission

Vanderbilt researchers aim to use AI to develop antibody therapies for any target

Study links ITSN1 gene variants to increased Parkinson's disease risk

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The evolution of OCT for retinal imaging and disease intervention

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Prof. Dr. Kristina Kusche-Vihrog