Immunology News and Research

Latest Immunology News and Research

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

Access to soil increases mice's resistance to allergic inflammations

When mice live in cages with an added earthen floor, it increases their resistance towards allergic inflammations. Close contact with micro-organisms in the soil triggers anti-inflammatory genes in the mice and stimulates their gut microbiota.

7 Aug 2018

Doxorubicin drug causes heart toxicity by disrupting the immune system

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure.

7 Aug 2018

Study highlights impact of silent viruses on how the host responds to vaccines

UC Davis researchers have shown that low levels of cytomegalovirus (CMV) have a significant impact on microbe and immune cell populations and how the immune system responds to the influenza vaccine. The study was published in the Journal of Virology.

3 Aug 2018

Study provides new insights into how asthma develops and progresses

Of the more than 24 million people in the U.S. who have asthma, 10 percent have severe asthma - a form of the disease that does not respond to treatment.

3 Aug 2018

CHOP experts identify new autoimmune disorder along with personalized treatment for young patient

Elijah Patino is a happy, healthy seven-year-old now, but it took a while to get there. For much of his life, he had a mysterious disease that made it painful to eat and painful to play.

2 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue transmission often precedes Zika virus infection, suggesting that women who previously acquired dengue immunity may be bitten by ZIKV-carrying mosquitoes during pregnancy.

2 Aug 2018

Study: Obesity may play role in flu transmission, not just disease severity

Obesity increases a person's risk for severe complications from influenza, including hospitalization and even death.

2 Aug 2018

Inhibiting a protein could enhance effectiveness of cancer immunotherapies

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy in the Johns Hopkins Kimmel Cancer Center discovered inhibiting a previously known protein could reduce tumor burdens and enhance the effectiveness of immunotherapy treatments.

31 Jul 2018

Researchers sequence complete mitochondrial genome of malaria mosquitoes

A team led by scientists from the Johns Hopkins Bloomberg School of Public Health has sequenced and annotated the first complete mitochondrial genome of Anopheles funestus, one of the main vectors of malaria in sub-Saharan Africa.

31 Jul 2018

Researchers discover new antibodies that have capacity to treat all Ebola viruses

Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans.

31 Jul 2018

Study finds tick bite meat allergy as most common cause of anaphylaxis

An increase in the Lone Star tick population since 2006, and the ability to recognize the ticks as the source of "alpha gal" allergy to red meat has meant significantly more cases of anaphylaxis being properly identified.

30 Jul 2018

Discovery opens up new ways to tackle growing threat of untreatable gonorrhea

Good news in the battle against the growing threat of drug-resistant “super gonorrhea”: Researchers at the University of Virginia School of Medicine and their collaborators in the United Kingdom have discovered a new way that the bacteria that cause gonorrhea resist the body’s immune defenses.

27 Jul 2018

Immunology News and Research

Latest Immunology News and Research

New CAR T-cell immunotherapy trial targets solid tumors

Access to soil increases mice's resistance to allergic inflammations

Doxorubicin drug causes heart toxicity by disrupting the immune system

Study highlights impact of silent viruses on how the host responds to vaccines

Study provides new insights into how asthma develops and progresses

CHOP experts identify new autoimmune disorder along with personalized treatment for young patient

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Study: Obesity may play role in flu transmission, not just disease severity

Inhibiting a protein could enhance effectiveness of cancer immunotherapies

Researchers sequence complete mitochondrial genome of malaria mosquitoes

Researchers discover new antibodies that have capacity to treat all Ebola viruses

Study finds tick bite meat allergy as most common cause of anaphylaxis

Discovery opens up new ways to tackle growing threat of untreatable gonorrhea

PEACHI project develops vaccine strategies targeting both HIV and hepatitis C virus

Research findings may offer new path to treat or prevent neurodegenerative diseases

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

Study observes how nanoplastics cause damage to DNA and cell membranes in mussels

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

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