Immunology News and Research

Latest Immunology News and Research

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

Pregnant women with higher levels of inflammatory cytokines and chemokines, proteins that control communication between cells of the immune system, may be at significantly greater risk of having a child with autism combined with intellectual disability, researchers with the UC Davis MIND Institute have found.

8 Jun 2016

New study identifies PDGFRα as key molecule for HCMV viral entry

A publication in the scientific journal Nature Microbiology identifies PDGFRα as the receptor for the trimeric gHgLgO complex of Human cytomegalovirus (HCMV).

7 Jun 2016

Combination immunotherapy may be better than one to combat metastatic melanoma

A new metastatic melanoma study suggests that a combination of two immunotherapies may be better than one.

7 Jun 2016

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients.

7 Jun 2016

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.

6 Jun 2016

Nivolumab drug shows better response rate in metastatic bladder cancer patients

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center.

6 Jun 2016

Study provides insight to gene shuffling process

Use of a new technique developed at the Babraham Institute has allowed researchers to take an in-depth look at the gene shuffling process that is responsible for our body's ability to recognise a vast range of foreign agents such as disease-causing microorganisms.

4 Jun 2016

Clinical study finds two topical skin creams as effective noninvasive treatments for low-risk superficial BCC

Basal cell carcinoma is one of the most common cancers and its incidence is increasing worldwide, putting a significant burden on health services. Topical treatments are available for superficial basal cell carcinoma (BCC) but there has a lack of long-term follow-up data to guide treatment decisions.

3 Jun 2016

Scientists discover master dimmer switches that control activity of immune cells

A person's genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. But little is known about how immune cells are pushed into overdrive.

3 Jun 2016

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Cancer immunotherapies--drugs that work by making a patient's immune system better at spotting and destroying tumor cells--are increasingly generating headlines. A number of these drugs are now being used for the treatment of melanoma, lung, and kidney cancers, and are showing promise in clinical trials with other diseases as well.

3 Jun 2016

Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Intestinal stem cells are among the most rapidly dividing cells in the body, busily creating new cells to replace the ones that are constantly being sloughed off. But unlike stem cells elsewhere in the body, those in the intestine are hidden away, and for good reason, it turns out.

3 Jun 2016

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

Researchers should include laboratory mice that are old and obese in their studies of immunotherapy treatments for cancer, according to a review article by Saint Louis University scientists.

2 Jun 2016

Clinical trial to test safety, efficacy of Roswell Park-developed SurVaxM in multiple myeloma patients

An immune-based therapy developed at Roswell Park Cancer Institute is moving forward with its third clinical trial. The early-stage clinical trial will assess whether SurVaxM — a cancer vaccine developed at Roswell Park — is a safe and effective treatment option for patients with multiple myeloma, a rare type of blood cancer.

1 Jun 2016

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Cryptococcus is a fungus found in the environment throughout the world that is able to cause disease in humans. While most fungal pathogens don’t receive as much press as their bacterial or viral counterparts, they can be just as deadly.

1 Jun 2016

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer.

1 Jun 2016

Scientists discover how Zika virus replicates in the placenta

Zika virus can infect and replicate in immune cells from the placenta, without killing them, scientists have discovered. The finding may explain how the virus can pass through the placenta of a pregnant woman, on its way to infect developing brain cells in her fetus.

28 May 2016

Researchers discover ANKRD55 gene linked to multiple sclerosis

The Ikerbasque researcher Koen Vandenbroeck, who heads the Neurogenomiks laboratory which reports to the Achucarro centre and the UPV/EHU-University of the Basque Country, together with other national and international groups, has shown that a genetic variant in the 5q11 chromosome, which is associated with susceptibility to developing multiple sclerosis, greatly regulates a gene known as ANKRD55. ANKRD55 is a gene with an unknown function.

28 May 2016

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

At noon every day, levels of genes and proteins throughout your body are drastically different than they are at midnight. Disruptions to this 24-hour cycle of physiological activity are why jet lag or a bad night's sleep can alter your appetite and sleep patterns for days--and even contribute to conditions like heart disease, sleep disorders and cancers.

27 May 2016

Study shows birth defects in immune system function may contribute to malnutrition

Malnourished children are most likely to die from common infections, not starvation alone, and immune disorder may be part of the cause, according to a review led by Queen Mary University of London.

27 May 2016

Malaria parasites use complement system to evade human immune response, study finds

The malaria parasite Plasmodium falciparum hijacks an immune system process to invade red blood cells, according to a study led by researchers at Penn State College of Medicine. Understanding how malaria invades the cells could lead to a more effective vaccine.

26 May 2016

Immunology News and Research

Latest Immunology News and Research

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

New study identifies PDGFRα as key molecule for HCMV viral entry

Combination immunotherapy may be better than one to combat metastatic melanoma

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

Nivolumab drug shows better response rate in metastatic bladder cancer patients

Study provides insight to gene shuffling process

Clinical study finds two topical skin creams as effective noninvasive treatments for low-risk superficial BCC

Scientists discover master dimmer switches that control activity of immune cells

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

Clinical trial to test safety, efficacy of Roswell Park-developed SurVaxM in multiple myeloma patients

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Scientists discover how Zika virus replicates in the placenta

Researchers discover ANKRD55 gene linked to multiple sclerosis

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

Study shows birth defects in immune system function may contribute to malnutrition

Malaria parasites use complement system to evade human immune response, study finds

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