Immunology News and Research

Latest Immunology News and Research

Daratumumab achieves 29.2% overall response rate in heavily pre-treated patients with multiple myeloma

Data from the international, multi-center, open-label, two-part, single-arm Phase 2 MMY2002 (SIRIUS) trial show treatment with single-agent daratumumab – an investigational, human anti-CD38 monoclonal antibody – achieved an overall response rate (ORR) of 29.2 percent (95% CI, 20.8-38.9), as assessed by an independent review committee, in heavily pre-treated patients with multiple myeloma.

30 May 2015

Presence of collagen in tumor microenvironment can be either good or bad

The presence of collagen in the tumor microenvironment, essentially where the tumor lives, can be either good or bad according to Constance Brinckerhoff, PhD who led the Dartmouth team's reporting of "The BRAFV600E inhibitor, PLX4032, increases type 1 collagen synthesis in melanoma cells," in Matrix Biology Journal.

30 May 2015

MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

The world's leading organization of oncologists will honor Jim Allison, Ph.D., for his pioneering research that led to a new way to treat cancer by unleashing an immune system attack rather than targeting tumors directly.

30 May 2015

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Duke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).

29 May 2015

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS).

28 May 2015

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the initiation of CALLISTO, a new comprehensive clinical research program for their novel oral anticoagulant, rivaroxaban, in patients with active cancer. The studies are evaluating the medicine for the prevention and treatment of life-threatening blood clots in patients with a wide range of cancer types.

28 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

A new study has demonstrated that a protein called Niemann-Pick C1 (NPC1) is critical for the Ebola virus to infect a host. The study, published in the May/June issue of mBio, the online open-access journal of the American Society for Microbiology, suggests that drugs that block NPC1 could be used to treat this deadly disease.

27 May 2015

Risk for obesity-associated diseases significantly higher for males than females

Obesity may be tougher on male immune systems than females, a new study in mice at the University of Michigan Medical School suggests.

27 May 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

Microfluidic cell-squeezing device could introduce specific antigens inside immune system's B cells

MIT researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system's B cells, providing a new approach to developing and implementing antigen-presenting cell vaccines.

22 May 2015

Bacterium can use cell-content sharing to repair damaged siblings

A University of Wyoming faculty member led a research team that discovered a certain type of soil bacteria can use their social behavior of outer membrane exchange (OME) to repair damaged cells and improve the fitness of the bacteria population as a whole.

22 May 2015

Chemical compound shows promise in treating rheumatoid arthritis

Montana State University researchers and their collaborators have published their findings about a chemical compound that shows potential for treating rheumatoid arthritis.

22 May 2015

Women more likely to be hospitalised after asthma emergency care

US research shows that women who attend the emergency department with acute asthma are almost twice as likely to be admitted to hospital than men despite several measures of asthma control, treatment and severity being more favourable in women.

21 May 2015

Existing anti-stroke drug can be effective in treating middle-ear infections

An existing anti-stroke drug is an effective treatment for middle-ear infections, showing the ability to suppress mucus overproduction, improve bacterial clearance and reduce hearing loss, according to researchers at Georgia State University and the University of Rochester.

21 May 2015

Novel drug target identified for treating rheumatoid arthritis

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.

21 May 2015

Research shows how immune system controls biological clock in times of inflammation, infection

Researchers at Trinity College Dublin and the University of Pennsylvania have uncovered an important link between our body clock and the immune system that will have relevance to the treatment of inflammatory and infectious diseases.

20 May 2015

Study shows trophon EPR effective in inactivating high-risk, cancer-causing HPV

A new study presented at the Society for Healthcare Epidemiology of America has demonstrated that the trophon EPR is the only high level disinfection system proven to kill natural, infectious, high-risk human papilloma virus (HPV) under normal use conditions.

20 May 2015

Study shows trophon EPR effective in inactivating high-risk, cancer-causing HPV

20 May 2015

New research points to potential therapeutic target for treating multiple sclerosis

New research into the causes of the excessive inflammation that drives multiple sclerosis has identified a faulty "brake" within immune cells, a brake that should be controlling the inflammation. This points to a potential target for developing new therapies to treat multiple sclerosis and could have important implications for other autoimmune diseases, such as the colon disease colitis and the chronic skin condition atopic dermatitis.

20 May 2015

Immunology News and Research

Latest Immunology News and Research

Daratumumab achieves 29.2% overall response rate in heavily pre-treated patients with multiple myeloma

Presence of collagen in tumor microenvironment can be either good or bad

MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Novel discovery offers new insight into why women more likely than men to develop MS

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

Risk for obesity-associated diseases significantly higher for males than females

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Microfluidic cell-squeezing device could introduce specific antigens inside immune system's B cells

Bacterium can use cell-content sharing to repair damaged siblings

Chemical compound shows promise in treating rheumatoid arthritis

Women more likely to be hospitalised after asthma emergency care

Existing anti-stroke drug can be effective in treating middle-ear infections

Novel drug target identified for treating rheumatoid arthritis

Research shows how immune system controls biological clock in times of inflammation, infection

Study shows trophon EPR effective in inactivating high-risk, cancer-causing HPV

Study shows trophon EPR effective in inactivating high-risk, cancer-causing HPV

New research points to potential therapeutic target for treating multiple sclerosis

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging