Immunology News and Research

Latest Immunology News and Research

Epigenetic mechanisms maintain tolerance in T cells specific for self antigens

At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens).

14 Feb 2012

Promising compound may counteract HIV's ability to hijack CD59 protein

One of the frustrations for scientists working on HIV/AIDS treatments has been the human immunodeficiency virus' ability to evade the body's immune system. Now an Indiana University researcher has discovered a compound that could help put the immune system back in the hunt.

14 Feb 2012

Starving HIV virus could be the basis for future therapy: Study

In a medical breakthrough researchers at NYU Langone Medical Center and colleagues have shown how some cells in the body can repel attacks from HIV by starving the virus of the building blocks of life.

13 Feb 2012

SAMHD1 protein cuts off raw material that HIV needs to create DNA and replicate

A protein that protects some of our immune cells from the most common and virulent form of HIV works by starving the virus of the molecular building blocks that it needs to replicate, according to research published online in Nature Immunology.

13 Feb 2012

Study reveals how SAMHD1 works to protect dendritic cells from HIV virus

A novel discovery by researchers at NYU Langone Medical Center and colleagues reveals a mechanism by which the immune system tries to halt the spread of HIV. Harnessing this mechanism may open up new paths for therapeutic research aimed at slowing the virus' progression to AIDS. The study appears online ahead of print today in Nature Immunology.

12 Feb 2012

Study investigates how cytokine IFN-λ release is regulated

In new research appearing in this month's issue of the journal Nature Immunology, Roy Curtiss, director of the Center for Infectious Diseases and Vaccinology at the Biodesign Institute at Arizona State University, along with international collaborators, investigates the coordination of a particular type of immune response, involving the release of of IFN-λ- a cell-signaling protein molecule known as a cytokine.

10 Feb 2012

Scientists identify single prion protein that causes neuronal death

Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger prion species.

10 Feb 2012

UofL to receive Grand Challenges tuberculosis biomarkers grant

The University of Louisville announced today that it will receive a tuberculosis (TB) biomarkers grant through the Bill & Melinda Gates Foundation's Grand Challenges in Global Health program, an initiative which seeks to overcome persistent bottlenecks in creating new tools that can radically improve health in the developing world. James E. Graham, Ph.D., associate professor of microbiology and immunology at the UofL School of Medicine, will pursue an innovative research project to identify and validate TB biomarkers, titled "Disposable Sampling Plate and Breath Test to Identify Patients with Active Tuberculosis."

10 Feb 2012

Early-life farm environment increases number of regulatory T-lymphocytes

Immunological diseases, such as eczema and asthma, are on the increase in westernised society and represent a major challenge for 21st century medicine. A new study has shown, for the first time, that growing up on a farm directly affects the regulation of the immune system and causes a reduction in the immunological responses to food proteins.

9 Feb 2012

DNA sequencing can direct immune system to attack cancer

DNA sequences from tumor cells can be used to direct the immune system to attack cancer, according to scientists at Washington University School of Medicine in St. Louis.

9 Feb 2012

Mary Ann Liebert to launch BioResearch Open Access in March

BioResearch Open Access, a new bimonthly peer-reviewed open access journal, will launch in March 2012 by Mary Ann Liebert, Inc., publishers.

9 Feb 2012

Researchers discover molecules that differentiate early-stage breast tumors from invasive cancer

Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness of invasive tumors, and with the time to metastasis and overall survival.

8 Feb 2012

Soft drink consumption associated with increased chance of asthma, COPD

A new study published in the journal Respirology reveals that a high level of soft drink consumption is associated with asthma and/or chronic obstructive pulmonary disease (COPD).

8 Feb 2012

Tailoring TB treatment based on a patient's genetic sequence

A gene that influences the inflammatory response to infection may also predict the effectiveness of drug treatment for a deadly form of tuberculosis.

8 Feb 2012

High soft drink consumption associated with asthma and COPD

A new study published in the journal Respirology reveals that a high level of soft drink consumption is associated with asthma and/or chronic obstructive pulmonary disease (COPD).

7 Feb 2012

Combination of ICS and LABA appears to reduce severe asthma attacks

A Henry Ford Hospital study has found that using two types of common asthma medications in combination reduces severe asthma attacks.

6 Feb 2012

Asian bird flu update for Ferbruary 2012

Health workers in Nepal are to cull thousands of chickens following the discovery of the H5N1 strain of bird flu in the southeastern part of the Himalayan country.

6 Feb 2012

CD74 molecule plays a guiding role in immune responses against diseases

University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.

6 Feb 2012

Smoking cessation reduces coughing, other respiratory symptoms within weeks

If the proven long-term benefits of smoking cessation are not enough to motivate young adults to stop smoking, a new study shows that 18- to 24-year olds who stop smoking for at least two weeks report substantially fewer respiratory symptoms, especially coughing.

4 Feb 2012

Increased exposure to sunlight may prevent allergies and eczema

Increased exposure to sunlight may reduce the risk of both food allergies and eczema in children, according to a new scientific study published this week.

4 Feb 2012