Immunology News and Research

Latest Immunology News and Research

Study shows how IgA acts as a "tuner" to keep the immune system in check

IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers.

26 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

New research suggests that the immune system’s ability to respond to spinal-cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

25 May 2023

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

24 May 2023

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Weill Cornell Medicine has been awarded a five-year, $11.6 million grant from the National Institute on Drug Abuse of the National Institutes of Health to study the effects cannabis, including marijuana and compounds derived from it, may have on the brains of those living with HIV.

23 May 2023

Exploring nutritional factors during pregnancy and in infancy to find clues for childhood tooth decay

Researchers from Rochester Institute of Technology and the University of Rochester Medical Center are taking a closer look at nutritional factors during pregnancy and in infancy associated with severe tooth decay in young children.

23 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

Understanding the cause for suboptimal germinal center response in aged mice

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

22 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.

15 May 2023

Researchers develop a computational approach to predict diabetic kidney disease

Researchers from Sanford Burnham Prebys and the Chinese University of Hong Kong have developed a computational approach to predict whether a person with type 2 diabetes will develop kidney disease, a frequent and dangerous complication of diabetes.

15 May 2023

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

An important genetic mechanism of drug resistance in one of the deadliest human malaria parasites has been identified in a new study published in Nature Microbiology.

11 May 2023

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms.

10 May 2023

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

Researchers from Cima University of Navarra (Spain) have shown in animal models of Alzheimer's disease that inhaling menthol improves cognitive ability.

10 May 2023

Immunology News and Research

Latest Immunology News and Research

Study shows how IgA acts as a "tuner" to keep the immune system in check

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Exploring nutritional factors during pregnancy and in infancy to find clues for childhood tooth decay

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Understanding the cause for suboptimal germinal center response in aged mice

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Novel computational platform can expand the pool of cancer immunotherapy targets

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

Researchers develop a computational approach to predict diabetic kidney disease

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

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