Immunology News and Research

Latest Immunology News and Research

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway.

19 Dec 2022

Scientists make breakthrough in understanding how inflammation is regulated

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.

16 Dec 2022

Origins of the serious cancer-like disease LCH discovered

The origins of the serious cancer-like disease LCH have been identified by researchers from Karolinska Institutet in collaboration with Karolinska University Hospital. The findings presented in Science Immunology may lead to new, targeted treatments.

16 Dec 2022

Mucosal DNA vaccine provides protection against lethal SARS-CoV-2 in mice

Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections.

16 Dec 2022

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Scientists at UC San Francisco have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells.

16 Dec 2022

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

Using synthetic gene circuits to better control the timing of immunotherapy

In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors happens on longer timescales.

16 Dec 2022

Study uncovers new immune target to treat atherosclerosis

For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins.

16 Dec 2022

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

In a recent study posted to the medRxiv* preprint server, researchers in Australia and Switzerland evaluated the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in community-based settings of the United States (US).

13 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

A nasal COVID-19 vaccine based on technology licensed from Washington University in St. Louis has been approved for emergency use in India as a booster for people who have already received two doses of other COVID-19 vaccines.

9 Dec 2022

HIV-positive people are protected by Covid vaccines

People infected with HIV who receive antiretroviral therapy form antibodies against Sars-Cov-2 after being vaccinated against Covid with mRNA vaccines.

9 Dec 2022

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

The George Washington University Vaccine Research Unit in partnership with Scripps Research, IAVI, Fred Hutchinson Cancer Center (FHCC) and the National Institutes of Health, National Institute of Allergy and Infectious Diseases Vaccine Research Center published the results of their Phase 1 Clinical Trial in Science.

8 Dec 2022

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Research led by Randal J. Kaufman, Ph.D., has found that misfolded proteins in liver cells contribute to the development of liver cancer, shedding new light on the mysterious origins of one of the world's deadliest diseases.

7 Dec 2022

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer, caused by abnormal overgrowth of cells, is the second-leading cause of death in the world. Researchers from the Salk Institute have zeroed in on specific mechanisms that activate oncogenes, which are altered genes that can cause normal cells to become cancer cells.

7 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

Immunology News and Research

Latest Immunology News and Research

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Scientists make breakthrough in understanding how inflammation is regulated

Origins of the serious cancer-like disease LCH discovered

Mucosal DNA vaccine provides protection against lethal SARS-CoV-2 in mice

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

Using synthetic gene circuits to better control the timing of immunotherapy

Study uncovers new immune target to treat atherosclerosis

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

An epigenetic modification improves the defense against infections, research shows

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

HIV-positive people are protected by Covid vaccines

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer immunotherapies can become more potent depending on the time of day

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

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