Immunology News and Research

Latest Immunology News and Research

New delivery method enhances the "attack power" of CAR T cells against tumors

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient's T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Researchers reveal why people with allergic asthma are protected from severe COVID

The vast majority of people infected with the omicron variant of SARS-CoV-2 experience mild cold-like symptoms, moderate flu-like symptoms, or no symptoms at all, but the virus is so transmissible that it still spread deep into lung tissue to cause severe disease and death in thousands of people in the United States in 2022 alone.

7 Apr 2022

Developing and manufacturing custom recombinant antibodies for R&D

In this interview, Dr. Linlin Zhang, technical specialist for Sino Biological Europe, discusses how Sino is expanding its product offerings into the European market and outlines its process for developing and manufacturing custom recombinant antibodies for their clients.

From Sino Biological Inc. 6 Apr 2022

Emergency C-section may compromise development and long-term health of babies

Labor and natural childbirth causes stress on a mother’s body but an emergency Caesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows.

6 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B cell signaling acts as both a red light to signaling in healthy cells and a green light to signaling in immune-deficient cells.

4 Apr 2022

The effect of COVID-19 on the lung function of young adults

Researchers evaluate whether SARS-CoV-2 infection has a negative impact on lung function in young adults who experienced mild to moderate COVID-19.

3 Apr 2022

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

1 Apr 2022

Tulane researchers show how COVID-19 affects the central nervous system

COVID-19 patients commonly report having headaches, confusion and other neurological symptoms, but doctors don't fully understand how the disease targets the brain during infection.

1 Apr 2022

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

The work investigated why the children experienced milder COVID-19 illness even after a strong immune response.

1 Apr 2022

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Faculty from the Departments of Microbiology, Medicine Genetics and Genomic Sciences, and Pathology and Molecular Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai play key roles in a National Institutes of Health (NIH) program set up to provide a real-time risk assessment of variants of SARS-CoV-2, the virus that causes COVID-19. The program, called SARS-CoV-2 Assessment of Viral Evolution (SAVE) and described in a paper published March 31 in Nature, assesses how the variants might affect transmission, virulence, and resistance to both disease-induced (convalescent) and vaccine-induced immunity.

31 Mar 2022

$2.05 million to support UTHSC's advanced genetics project on breast cancer

A University of Tennessee Health Science Center team has received $2.05 million from the National Cancer Institute for an advanced genetics project that could help develop targeted therapies and personalized treatment for breast cancer. Liza Makowski, PhD, professor of Hematology and Oncology in the College of Medicine, is the lead investigator on the award.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

New tissue-clearing method could speed the study of many disease-related biological processes

Scientists at Scripps Research have unveiled a new tissue-clearing method for rendering large biological samples transparent.

29 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Immunology News and Research

Latest Immunology News and Research

New delivery method enhances the "attack power" of CAR T cells against tumors

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Researchers reveal why people with allergic asthma are protected from severe COVID

Developing and manufacturing custom recombinant antibodies for R&D

Emergency C-section may compromise development and long-term health of babies

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The effect of COVID-19 on the lung function of young adults

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Tulane researchers show how COVID-19 affects the central nervous system

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

$2.05 million to support UTHSC's advanced genetics project on breast cancer

Role of SARS-CoV-2 S1 subunit in severe COVID-19

SARS-CoV-2 and pandemic chilblains

A ferritin nanoparticle candidate vaccine for COVID

New tissue-clearing method could speed the study of many disease-related biological processes

The different actions of CBD in SARS-CoV-2 infection

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

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