Immunology News and Research

Latest Immunology News and Research

Naturally occurring protein associated with better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

SARS-CoV-2 infection may prompt Guillain-Barré syndrome

A new paper in Brain, published by Oxford University Press, indicates that a COVID-19 infection may prompt Guillain-Barré syndrome.

23 Sep 2021

Researchers unravel the structure of bacterial appendages

A research team led by David Thanassi, PhD, of Stony Brook University, has used molecular biology and cryoelectron microscopy to successfully unravel the structure of bacterial appendages called P pili.

22 Sep 2021

New framework needed to explore links between evolved pathogen tolerance and emerging infections

A new multidisciplinary research framework is needed to explore links between evolved tolerance to pathogens and their spillover into humans, scientists write today in the journal eLife.

22 Sep 2021

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway. These findings were published online in Cancer Research, a journal of the American Association for Cancer Research, and point to a new therapeutic opportunity for this type of ovarian cancer for which new solutions are urgently needed.

22 Sep 2021

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Scientists from the University of Oxford and the Ludwig Institute for Cancer Research are building on the success of the Oxford-AstraZeneca vaccine against SARS-CoV-2 to develop a vaccine to treat cancer.

21 Sep 2021

Researchers identify prediction markers which can be used to define COVID-19 severity

An estimated 14−17% of hospitalized COVID-19 patients develop a severe form of the disease, requiring oxygen support and admission to the intensive care unit.

20 Sep 2021

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

A study led by UT Southwestern dermatologists suggests that a common inflammatory skin condition may stem from poorly regulated sex hormones.

20 Sep 2021

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

Allergic reactions to the new mRNA-based COVID-19 vaccines are rare, typically mild and treatable, and they should not deter people from becoming vaccinated, according to research from the Stanford University School of Medicine.

20 Sep 2021

New discovery reveals how immune 'sentinel' cells are maintained

WEHI researchers have made a surprise discovery about how immune 'sentinel' cells are maintained, which could have implications for drugs in development for treating cancer.

20 Sep 2021

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus.

18 Sep 2021

Study uncovers five new genetic loci predisposing to atopic dermatitis

An international study led by the University of Oulu's researchers reports five new genetic loci predisposing to atopic dermatitis.

18 Sep 2021

Scientists discover new cell type in human skin that contributes to inflammatory skin diseases

A team of international scientists and clinical experts have unraveled a new cell type in human skin that contributes to inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis (PSO). Their study findings were published in the Journal of Experimental Medicine in September 2021.

17 Sep 2021

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

17 Sep 2021

Temple research paves the way for first Phase 1/2 clinical trials of CRISPR-based therapy for HIV

For the last seven years, researchers at the Lewis Katz School of Medicine at Temple University have been developing and refining CRISPR-based gene-editing technology for the treatment of human immunodeficiency virus type 1 (HIV) infection.

17 Sep 2021

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease.

17 Sep 2021

Discovery of biological response platform could provide opportunity to alleviate allergic inflammation

New discoveries about a built-in rapid reaction system that triggers inflammatory responses when people are exposed to allergens, such as insects, mites, and fungi, also may hold the keys to helping more people manage their allergies in years to come.

17 Sep 2021

New vaccine platform can better induce anti-malaria immunity in the liver

Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver.

16 Sep 2021

Study points to a possible new approach for treating MRSA superbug

A study released in STEM CELLS Translational Medicine, by researchers at the Baker Institute for Animal Health, part of Cornell University's College of Veterinary Medicine, Ithaca, N.Y., details in a relevant ex vivo model how treating wounds with the secretion of a type of stem cell called mesenchymal stromal cell (MSC) effectively reduced methicillin-resistant Staphylococcus aureus – better known as MRSA viability and stimulated the surrounding skin cells to build up a defense against the bacterial invader.

16 Sep 2021

Fatal COVID-19 infections linked to poor immune responses and elevated MAIT cell activation

The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological factors associated with death in critically ill COVID-19 patients are poorly understood.

16 Sep 2021

Immunology News and Research

Latest Immunology News and Research

Naturally occurring protein associated with better stroke recovery in mice

SARS-CoV-2 infection may prompt Guillain-Barré syndrome

Researchers unravel the structure of bacterial appendages

New framework needed to explore links between evolved pathogen tolerance and emerging infections

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Researchers identify prediction markers which can be used to define COVID-19 severity

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

New discovery reveals how immune 'sentinel' cells are maintained

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

Study uncovers five new genetic loci predisposing to atopic dermatitis

Scientists discover new cell type in human skin that contributes to inflammatory skin diseases

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

Temple research paves the way for first Phase 1/2 clinical trials of CRISPR-based therapy for HIV

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

Discovery of biological response platform could provide opportunity to alleviate allergic inflammation

New vaccine platform can better induce anti-malaria immunity in the liver

Study points to a possible new approach for treating MRSA superbug

Fatal COVID-19 infections linked to poor immune responses and elevated MAIT cell activation

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