Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is an ongoing or chronic health problem that causes inflammation and swelling in the digestive tract. The irritation causes bleeding sores called ulcers to form along the digestive tract. This in turn can cause crampy, abdominal pain and severe bloody diarrhea.

What is Ulcerative Colitis?

Ulcerative colitis is a chronic condition that affects the large intestines, particularly the colon. It is classified as one of the two inflammatory bowel diseases along with Crohn’s disease.

Ulcerative Colitis Causes

Genetics of Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD) in Pregnancy

Dysbiosis and the Microbiome

Mesentery: a new organ?

FODMAP Research

Inflammatory Bowel Disease and Colorectal Cancer

Short-Chain Fatty Acids (SCFAs)

Latest Inflammatory Bowel Disease News and Research

Link between inflammatory bowel disease and spondyloarthritis revealed

There is a strong connection between inflammatory bowel disease (IBD) and spondyloarthritis - a condition that causes pain and stiffness in the joints.

28 Oct 2024

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis.

26 Oct 2024

Genetic variant identified as potential predictor for severe ulcerative colitis

The HLA-DRB1*01:03 genetic variant is associated with severe ulcerative colitis, significantly raising the risk of major surgeries and hospitalizations.

21 Oct 2024

Blood test predicts preeclampsia risk in laboring women

A simple blood test could help doctors identify women in labor who are at risk for preeclampsia -; a leading cause of maternal death -; and take precautions to prevent it, according to research presented at the ANESTHESIOLOGY 2024 annual meeting.

20 Oct 2024

Studies reveal unique challenges faced by younger patients with colorectal cancer

Younger adults with colon cancer tend to be diagnosed at a later stage and have more aggressive types of tumors.

18 Oct 2024

Revolutionizing precision nutrition with gut microbiome insights

Researchers at Rutgers University-New Brunswick, along with international collaborators, have introduced a novel method for identifying the crucial set of gut microbes commonly found in humans and essential for health.

18 Oct 2024

New genetic variant may predict severe ulcerative colitis in patients

Abdominal pain, diarrhea, and debilitating fatigue define the daily lives of millions of people worldwide who suffer from chronic bowel disease.

17 Oct 2024

Adenine base editors show potential to correct X-CGD-causing mutations

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder characterized by high susceptibility to infections.

16 Oct 2024

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024

Early signs of inflammatory bowel disease detected in newborns

Across the Western world, the prevalence of these chronic and serious conditions, which have no cure, is rising. In Denmark alone, 50,000 people suffer from either Crohn's disease or ulcerative colitis, which represents a doubling in cases over the past 20 years.

12 Oct 2024

Promising stool test and therapy on the horizon for endometriosis

Promising findings by researchers at Baylor College of Medicine and collaborating institutions could lead to the development of a non-invasive stool test and a new therapy for endometriosis, a painful condition that affects nearly 200 million women worldwide.

12 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

Baylor scientist earns NIH grant for personalized microbiome treatments

Baylor University researcher Aaron Wright, Ph.D., has earned a $5.6 million National Institutes of Health (NIH) Director's Transformative Research Award for a project that he and collaborators hope could lead to personalized – and revolutionary – treatments for gut microbiome diseases like Irritable Bowel Syndrome (IBS), Crohn's, Ulcerative Colitis and more.

9 Oct 2024

High-fiber diets transform gut microbiome, improving health across multiple diseases

Researchers identified two competing guilds of gut bacteria, one beneficial and one harmful, which can predict health outcomes and treatment success in diseases like type 2 diabetes.

8 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Autoimmune diseases more common in women who stop ovulating before 40

The study finds a significant correlation between premature ovarian insufficiency and autoimmune diseases, urging further investigation into prevention methods.

30 Sep 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Cleveland Clinic identifies bacterium that weakens gut immune defense

Cleveland Clinic researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases.

26 Sep 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease -; an autoimmune disorder -; is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

Targeted drug therapy shows promise for ulcerative colitis remission

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

26 Sep 2024

Inflammatory Bowel Disease

Overview

Ulcerative Colitis Causes

Genetics of Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD) in Pregnancy

Feature Articles

Dysbiosis and the Microbiome

Mesentery: a new organ?

FODMAP Research

Inflammatory Bowel Disease and Colorectal Cancer

Short-Chain Fatty Acids (SCFAs)

Latest Inflammatory Bowel Disease News and Research

Link between inflammatory bowel disease and spondyloarthritis revealed

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

Genetic variant identified as potential predictor for severe ulcerative colitis

Blood test predicts preeclampsia risk in laboring women

Studies reveal unique challenges faced by younger patients with colorectal cancer

Revolutionizing precision nutrition with gut microbiome insights

New genetic variant may predict severe ulcerative colitis in patients

Adenine base editors show potential to correct X-CGD-causing mutations

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Early signs of inflammatory bowel disease detected in newborns

Promising stool test and therapy on the horizon for endometriosis

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Baylor scientist earns NIH grant for personalized microbiome treatments

High-fiber diets transform gut microbiome, improving health across multiple diseases

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Autoimmune diseases more common in women who stop ovulating before 40

How viral persistence and immune dysfunction drive long COVID

Cleveland Clinic identifies bacterium that weakens gut immune defense

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Targeted drug therapy shows promise for ulcerative colitis remission

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Inflammatory Bowel Disease

Overview

Feature Articles

Dysbiosis and the Microbiome

Mesentery: a new organ?

FODMAP Research

Inflammatory Bowel Disease and Colorectal Cancer

Short-Chain Fatty Acids (SCFAs)

Latest Inflammatory Bowel Disease News and Research

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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