Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is an ongoing or chronic health problem that causes inflammation and swelling in the digestive tract. The irritation causes bleeding sores called ulcers to form along the digestive tract. This in turn can cause crampy, abdominal pain and severe bloody diarrhea.

What is Ulcerative Colitis?

Ulcerative colitis is a chronic condition that affects the large intestines, particularly the colon. It is classified as one of the two inflammatory bowel diseases along with Crohn’s disease.

Ulcerative Colitis Causes

Genetics of Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD) in Pregnancy

Dysbiosis and the Microbiome

Mesentery: a new organ?

FODMAP Research

Inflammatory Bowel Disease and Colorectal Cancer

Short-Chain Fatty Acids (SCFAs)

Latest Inflammatory Bowel Disease News and Research

New therapeutic cocktails show promise for long-lasting asthma relief

Current asthma treatments don't work in all patients, and they don't provide long-term relief from potentially deadly asthma attacks.

19 Feb 2025

Ginger's furanodienone compound may offer new treatment for inflammatory bowel disease

An international team led by researchers at the University of Toronto has found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD).

19 Feb 2025

Milk boosts gut-friendly bacteria while cheese alters microbiome balance, study reveals

Researchers found that dairy consumption influences gut microbiota composition, with milk promoting beneficial bacteria and cheese altering microbial diversity in distinct ways.

18 Feb 2025

Strengthening the gut barrier may halt Crohn’s disease progression

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease.

18 Feb 2025

Gut bacteria could one day serve as microscopic in-house pharmacists

Hundreds of different species of microbes live, laugh, and love in your gut. In the future, one of these might serve a new function: microscopic in-house pharmacist.

13 Feb 2025

Oral vancomycin induces PSC-IBD remission, driving gut microbiome and metabolic shifts

Findings indicate oral vancomycin induces remission in PSC-IBD, with notable microbiota changes and inflammation reduction, reversing after treatment ends.

13 Feb 2025

Vancomycin could offer new therapeutic option for patients with a type of inflammatory bowel disease

An antibiotic used to treat infective diarrhoea could be an effective drug for a type of inflammatory bowel disease, a new study has found.

10 Feb 2025

Mediterranean diet boosts quality of life—here’s how

A systematic review finds that following the Mediterranean diet is linked to better physical, mental, and social well-being, particularly in aging populations and those with chronic conditions.

10 Feb 2025

Innovative method sheds light on the proteins behind gut health

A new Weizmann Institute study identified all of the proteins in a stool sample – those from the microbiome, the human body and food – revealing the hidden secrets of the intestines and their impact on human disease

5 Feb 2025

Mayo Clinic researchers create organoid models for uveal melanoma study

Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.

29 Jan 2025

Oral fecal transplantation could help prevent graft-versus-host disease in stem cell transplant patients

A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood cancers.

28 Jan 2025

Innovative approach tracks SARS-CoV-2 in the blood to guide COVID-19 treatment

Investigators from Mass General Brigham have found that a method originally designed for cancer detection can also identify and monitor even tiny amounts of SARS-CoV-2 intact viral particles in blood and other fluids from patients with acute COVID-19 infections, creating the potential for guiding future treatment of patients. The research is published in Science Advances.

25 Jan 2025

A global look at the gut: Scientists highlight microbiome diversity

Researchers analyzed 168,464 samples to uncover how geographic and technical factors shape global gut microbiome variation, highlighting underrepresented regions and technical biases.

23 Jan 2025

AGA releases updated guidelines on hepatitis B reactivation in patients on immunosuppressive drugs

The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline in Gastroenterology addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.

23 Jan 2025

Multiple sclerosis linked to increased risk of perinatal mental illness

People with multiple sclerosis (MS) face a significantly higher risk of perinatal mental illness compared to those with other chronic conditions, according to a new study analyzing over 890,000 births in Ontario.

23 Jan 2025

New technique identifies SARS-CoV-2 in blood and other fluids with high sensitivity

22 Jan 2025

How gut microbiota impacts childhood obesity

Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite regulation, with emerging therapeutic strategies like probiotics, dietary interventions, and fecal microbiota transplantation showing promise.

21 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Tofacitinib reduces SARS-CoV-2 infection risk in patients with PTPN2 deficiency

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in PTPN2.

17 Jan 2025

Wearable devices can identify and predict flare-ups in inflammatory bowel disease

Wearable devices can identify, differentiate, and predict flare-ups, or the worsening of symptoms and inflammation, in inflammatory bowel disease (IBD), Mount Sinai researchers have shown in a first-of-its-kind study.

16 Jan 2025