Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

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Latest Lupus News and Research

Dextromethorphan found to have potential in treating lung fibrosis

Dextromethorphan found to have potential in treating lung fibrosis

Cellular RNA enhances MAVS signalosome activation in antiviral immunity

Cellular RNA enhances MAVS signalosome activation in antiviral immunity

Cough syrup ingredient may help combat lung fibrosis

Cough syrup ingredient may help combat lung fibrosis

NIH funding supports innovative lupus research using DNA mimic molecules

NIH funding supports innovative lupus research using DNA mimic molecules

Study pinpoints how a network of different proteins controls rest and activation

Study pinpoints how a network of different proteins controls rest and activation

Next-generation cell-penetrating antibodies could transform cancer treatment

Next-generation cell-penetrating antibodies could transform cancer treatment

Women with infertility have higher risk of developing systemic autoimmune diseases

Women with infertility have higher risk of developing systemic autoimmune diseases

Revolutionary strategy offers hope for type 1 diabetes treatment

Revolutionary strategy offers hope for type 1 diabetes treatment

New initiative aims to explore diet’s role in lupus care

New initiative aims to explore diet’s role in lupus care

Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Vitiligo linked to increased risk of heart disease and stroke, study finds

Novel antibodies show promise for tumor targeting and RAD51 inhibition

Novel antibodies show promise for tumor targeting and RAD51 inhibition

New study reveals mechanism of inflammation in lupus

New study reveals mechanism of inflammation in lupus

The new science behind the health benefits of caffeine

The new science behind the health benefits of caffeine

Caffeine's anti-inflammatory effects may help protect blood vessels

Caffeine's anti-inflammatory effects may help protect blood vessels

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Autoimmune diseases more common in women who stop ovulating before 40

Autoimmune diseases more common in women who stop ovulating before 40

Over 80% of women are iron deficient by their third trimester

Over 80% of women are iron deficient by their third trimester

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