Macular Degeneration News and Research

Latest Macular Degeneration News and Research

BrightFocus announces recipients of 2015 research program grants

BrightFocus Foundation, which funds research worldwide on Alzheimer's disease, glaucoma, and macular degeneration, today announced that its 2015 research program grants have been awarded to 58 scientists in 20 states and 7 foreign countries. Part of an $11 million research investment, the grants reflect the largest annual research funding in the foundation's history.

4 Aug 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

New method identifies preferred retinal locations in both eyes of patients with central vision loss

Eyes with central vision loss adapt by developing a new fixation point in a different part of the retina, called the preferred retinal location (PRL). Now for the first time, a new method makes it possible to identify PRLs in both eyes simultaneously, reports a study in the August issue of Optometry and Vision Science, official journal of the American Academy of Optometry.

29 Jul 2015

Low-dose lithium lowers involuntary motor movements in mouse model of Parkinson's disease

Low-dose lithium reduced involuntary motor movements - the troubling side effect of the medication most commonly used to treat Parkinson's disease (PD) - in a mouse model of the condition that is diagnosed in about 60,000 Americans each year. The third in a series of studies from the Andersen lab involving PD and low-dose lithium, the results add to mounting evidence that low-doses of the psychotropic drug could benefit patients suffering from the incurable, degenerative condition.

28 Jul 2015

New study suggests novel ways to treat serous retinal detachment

Wet age-related macular degeneration (AMD) is the leading cause of severe vision loss in older individuals. AMD and other serious chronic eye problems that affect younger individuals result when fluid accumulates abnormally under or within the retina. A new study published in The American Journal of Pathology shows for the first time that the release of substances from mast cells may be a causal factor in this type of eye pathology, and inhibitors of this release may offer new ways to treat serous retinal detachment.

22 Jul 2015

Current and new treatments for AMD: an interview with Dr Alan Cruess, AMD Alliance International

For two decades beginning in the late 1970’s through 2001, clinicians relied upon laser photocoagulation in the treatment of wet AMD caused by choroidal neovascularization. Attempts to obliterate the neovascular lesions often led to acute central visual loss and often, even with modest success, the lesions recurred with even more vision loss.

21 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

OphthaliX updates website to reflect proposed acquisition of Israel-based Improved Vision Systems

OphthaliX Inc., a clinical-stage company focused on developing products that treat and improve sight for people living with ophthalmic disorders, and a subsidiary of Can-Fite BioPharma Ltd., announced today it has launched an updated website, www.ophthaliX.com, to reflect its definitive agreement to acquire Israel-based Improved Vision Systems Ltd.

14 Jul 2015

Up-to-date treatment and diagnostic guidelines for diabetic retinal degeneration

Around 600,000 Austrians suffer from diabetes. This condition is frequently associated with serious retinal disorders. Along with age-related macular degeneration, diabetic retinal degeneration is one of the most common causes of blindness. The Department of Ophthalmology and Optometry at MedUni Vienna was chosen by the European Society of Retina Specialists (EURETINA) to coordinate the development of up-to-date treatment and diagnostic guidelines.

9 Jul 2015

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Progression and severity of macular atrophy are the main anatomical determinants of long-term visual outcomes in exudative age-related macular degeneration patients treated with ranibizumab, suggest SEVEN-UP study results.

8 Jul 2015

Study could provide paradigm shift in treatment of age-related disease, cancer

Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies.

7 Jul 2015

Researchers compare effectiveness of two stem cell types in treating retinal degeneration

By growing two types of stem cells in a "3-D culture" and measuring their ability to produce retinal cells, a team lead by St. Jude Children's Research Hospital researchers has found one cell type to be better at producing retinal cells.

3 Jul 2015

OCT angiography shows promise in CNV detection

Noninvasive optical coherence tomography angiography can successfully detect choroidal neovascularisation, research findings indicate.

30 Jun 2015

Polypoidal choroidal vasculopathy shows distinct classification

Researchers have found that idiopathic polypoidal choroidal vasculopathy has significant clinical differences to neovascular age-related macular degeneration and suggest that it should be considered a distinct entity.

30 Jun 2015

RPE transdifferentiation revealed in AMD

Subducted and melanotic cells in the eyes of patients with advanced age-related macular degeneration derive from two distinct retinal pigment epithelium phenotypes, research shows.

30 Jun 2015

ORT incidence increases in nAMD despite anti-VEGF treatment

Swiss researchers report that patients with neovascular age-related macular degeneration (nAMD) experience increased incidence of outer retinal tubulation over time, despite treatment with a vascular endothelial growth factor blocker.

30 Jun 2015

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Canada's first human gene therapy trial for eyes -- the replacement of a faulty gene with a healthy one -- is now underway at the Royal Alexandra Hospital to preserve and potentially restore vision for people with a genetic disorder that leaves them blind by middle age.

30 Jun 2015

iCo Therapeutics declares voting and election results from its 2015 Annual Meeting of Shareholders

iCo Therapeutics, today announced that all nominees listed in the management information circular dated June 1, 2015 were elected as directors at its 2015 Annual Meeting of Shareholders, held earlier today, June 26 2015.

27 Jun 2015

UAB optometrist offers tips to keep eyes healthy during summer months

While the warm summer months are perfect for spending time outside, several environmental factors can spell trouble for eyesight. One University of Alabama at Birmingham optometrist says knowledge of what to do, and what not to do, will keep eyes healthy.

26 Jun 2015

Bayer Yakuhin receives MHLW approval in Japan for EYLEA (aflibercept) Injection to treat RVO patients

Regeneron Pharmaceuticals, Inc. today announced that Bayer HealthCare's Japanese subsidiary, Bayer Yakuhin, Ltd., received approval for EYLEA (aflibercept) Injection by the Ministry of Health, Labour and Welfare (MHLW) in Japan for the treatment of patients with macular edema secondary to retinal vein occlusion (RVO).

26 Jun 2015

Macular Degeneration News and Research

Latest Macular Degeneration News and Research

BrightFocus announces recipients of 2015 research program grants

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

New method identifies preferred retinal locations in both eyes of patients with central vision loss

Low-dose lithium lowers involuntary motor movements in mouse model of Parkinson's disease

New study suggests novel ways to treat serous retinal detachment

Current and new treatments for AMD: an interview with Dr Alan Cruess, AMD Alliance International

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

OphthaliX updates website to reflect proposed acquisition of Israel-based Improved Vision Systems

Up-to-date treatment and diagnostic guidelines for diabetic retinal degeneration

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Study could provide paradigm shift in treatment of age-related disease, cancer

Researchers compare effectiveness of two stem cell types in treating retinal degeneration

OCT angiography shows promise in CNV detection

Polypoidal choroidal vasculopathy shows distinct classification

RPE transdifferentiation revealed in AMD

ORT incidence increases in nAMD despite anti-VEGF treatment

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

iCo Therapeutics declares voting and election results from its 2015 Annual Meeting of Shareholders

UAB optometrist offers tips to keep eyes healthy during summer months

Bayer Yakuhin receives MHLW approval in Japan for EYLEA (aflibercept) Injection to treat RVO patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Macular Degeneration News and Research

Latest Macular Degeneration News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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