Malaria News and Research

Latest Malaria News and Research

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

First meeting of the International Health Regulations Emergency Committee reports on mpox surge

The Director-General of the World Health Organization (WHO), having concurred with the advice offered by the International Health Regulations (2005) (IHR or Regulations) Emergency Committee regarding the upsurge of mpox 2024 during its first meeting, held on 14 August 2024, has determined, on the same date, that the ongoing upsurge of mpox in the Democratic Republic of the Congo (DRC) and in a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the provisions of the Regulations.

20 Aug 2024

Study reveals time-of-day impact on cerebral malaria severity

A discovery by McGill-affiliated researchers could lead to more effective treatment of malaria and other parasitic diseases.

19 Aug 2024

Pneumococcal vaccines could drastically reduce child deaths by 2030

Utilizing pneumococcal conjugate vaccines (PCVs) could save almost 700,000 children's lives between the time of their introduction to the year 2030, according to a new modeling study. This would be equivalent to the average number of babies born in the UK each year.

16 Aug 2024

Breakthrough malaria vaccine offers long-term protection for pregnant women

In a report published in The Lancet Infectious Diseases (Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomized, double-blind, placebo-controlled, phase 1 and 2 trials) a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable protective efficacy against malaria shown by Sanaria® PfSPZ Vaccine when administered to women prior to pregnancy.

14 Aug 2024

Experimental malaria vaccine shows promise in protecting pregnant women

Two National Institutes of Health (NIH)-supported trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe.

14 Aug 2024

ANU researchers develop cholesterol-based trojan horse method to target malaria parasites

More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive.

13 Aug 2024

Pioneering study brings leishmaniasis vaccine development closer

Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body's immune response, bringing a vaccine for the neglected tropical disease a step closer.

2 Aug 2024

Climate change-driven migrations worsen infectious diseases in vulnerable regions

Climate change-driven migrations increase infectious disease risks by spreading pathogens and overcrowding vulnerable regions, demanding urgent, targeted interventions.

1 Aug 2024

How insecticide resistance in household pests fuels malaria resurgence

For decades, insecticide-treated bed nets and indoor insecticide spraying regimens have been important – and widely successful – treatments against mosquitoes that transmit malaria, a dangerous global disease. Yet these treatments also – for a time – suppressed undesirable household insects like bed bugs, cockroaches and flies.

23 Jul 2024

Breakthrough malaria vaccines RTS,S and R21 poised to save thousands of lives

Research paper reviews the efficacy of the first licensed malaria vaccines, RTS,S and R21, highlighting their potential to significantly reduce childhood mortality and discussing future vaccine development strategies.

21 Jul 2024

Extreme heat alert: Understanding the impact of heatwaves on public health

According to a joint heat-health warning issued by the UK Health Security Agency (UKHSA) and Met Office, parts of the UK are forecast to experience heatwave conditions as temperatures rise over the next few days in July.

19 Jul 2024

Urgent strategies needed to fight artemisinin resistance in East Africa

Artemisinin-based combination therapies (ACTs) have become the cornerstone of malaria treatment and control.

19 Jul 2024

Poll: Majority of Brits fear cancer diagnosis more than any other condition

Two-thirds of the public say they are very or somewhat worried about being told they have the disease – higher than for any other medical condition, including dementia and having a heart attack – according to polling released today.

14 Jul 2024

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

Comprehensive review highlights Aloe vera's versatile biological activities and its potential applications in medicine and cosmetics while addressing its safety concerns.

11 Jul 2024

SRI’s novel injectable formulation aims to provide a better option to fight malaria

SRI today announced that researchers are developing a new treatment that aims to provide a better option to fight malaria, particularly for people in low-income and rural regions.

2 Jul 2024

CRISPR-based genetic technique eradicates malaria mosquitoes with over 99% efficiency

Scientists at the University of California have developed a precision-guided sterile insect technique to eliminate Anopheles gambiae mosquitoes, achieving over 99.5% male sterility and 99.9% female lethality, effectively suppressing malaria transmission.

26 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control.

24 Jun 2024

Artemisinins: A new hope for women with polycystic ovary syndrome

Plant-derived compounds best known for their antimalarial properties relieve polycystic ovary syndrome, a major public health problem that affects millions of women worldwide.

13 Jun 2024

Malaria News and Research

Latest Malaria News and Research

Spatial transcriptomics unlocks malaria's liver stage secrets

First meeting of the International Health Regulations Emergency Committee reports on mpox surge

Study reveals time-of-day impact on cerebral malaria severity

Pneumococcal vaccines could drastically reduce child deaths by 2030

Breakthrough malaria vaccine offers long-term protection for pregnant women

Experimental malaria vaccine shows promise in protecting pregnant women

ANU researchers develop cholesterol-based trojan horse method to target malaria parasites

Pioneering study brings leishmaniasis vaccine development closer

Climate change-driven migrations worsen infectious diseases in vulnerable regions

How insecticide resistance in household pests fuels malaria resurgence

Breakthrough malaria vaccines RTS,S and R21 poised to save thousands of lives

Extreme heat alert: Understanding the impact of heatwaves on public health

Urgent strategies needed to fight artemisinin resistance in East Africa

Poll: Majority of Brits fear cancer diagnosis more than any other condition

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

SRI’s novel injectable formulation aims to provide a better option to fight malaria

CRISPR-based genetic technique eradicates malaria mosquitoes with over 99% efficiency

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

Artemisinins: A new hope for women with polycystic ovary syndrome

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Malaria News and Research

Latest Malaria News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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