Male Infertility News and Research

Latest Male Infertility News and Research

Penn researchers track defective sperm epigenome linked to male infertility

One out of eight couples has trouble conceiving, with nearly a quarter of those cases caused by unexplained male infertility. For the past decade, research has linked that infertility to defective sperm that fail to "evict" proteins called histones from DNA during development.

16 Dec 2019

Important discovery about male infertility could lead to new treatments

Using a new mouse model, Penn Medicine researchers have identified defects in the sperm epigenome that cause male infertility.

16 Dec 2019

Why some sperm swim in circles – it’s a protein defect

A new study published in the journal PNAS shows that some sperm cannot swim straight because they lack a protein called VSP. This motility defect seriously impacts the rates of successful fertilization. In addition, VSP is also found to regulate the amount of calcium that enters the flagellum, the whiplike organelle that propels the sperm towards the waiting ovum or egg. This important discovery may help treat infertility more effectively.

3 Dec 2019

Researchers discover genes linked to sex ratio and male fertility in mice

One of the more recent trends among parents-to-be is the so-called gender reveal, a party complete with pink or blue cake to answer the burning question, "Is it a boy or girl?" After all, it's presumed that there's a 50-50 chance you'd have one or the other.

18 Oct 2019

Father’s nutritional pattern affects child’s cardiovascular health

While couples often change their lifestyle in order to conceive faster, including crash diets, a new study in mice throws up the possibility that this kind of extreme dietary modification by the father might result in adverse effects on the child conceived in this manner.

17 Oct 2019

St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

St George Street Capital, a UK registered charity, has signed a license agreement with AstraZeneca to develop two compounds in the clinic: one for idiopathic male infertility, and the other for renal transplant rejection. The agreement enables additional compounds to be added in the future.

From AstraZeneca 14 Oct 2019

Study highlights potential impact of chlamydia infection on men's fertility

The potential impact of undiagnosed sexually transmitted chlamydia infection on men's fertility has been highlighted in a study led by Queensland University of Technology (QUT), which for the first time found chlamydia in the testicular tissue biopsies of infertile men whose infertility had no identified cause.

9 Oct 2019

Study shows miRNAs in semen as non-invasive biomarkers for prostate cancer

Researchers of the Human Molecular Genetics group at the Bellvitge Biomedical Research Institute, led by Dr. Sara Larriba, in collaboration with Dr. Francesc Vigués and Dr. Manel Castells of the Urology Service of Bellvitge University Hospital, show the usefulness of certain molecules, the miRNAs in semen, as non-invasive biomarkers for prostate cancer.

26 Sep 2019

Prostate cancer risk linked to assisted reproduction techniques

A study published in BMJ has revealed a link between the risk of prostate cancer and men who have become fathers via assisted reproduction techniques.

26 Sep 2019

NIH grants totaling $2.8 million focus on pinpointing male fertility genes

Pinpointing the genes responsible for male fertility is the focus of two National Institutes for Health grants totaling $2.8 million.

20 Sep 2019

New computational method reveals genetic patterns in massive jumble of cells

Scientists have devised a new computational method that reveals genetic patterns in the massive jumble of individual cells in the body.

5 Aug 2019

Data collected by ESHRE show rise in use of IVF in infertility treatment

The latest annual data collected by ESHRE from European national registries show another rise in the cumulative use of IVF in the treatment of infertility, although success rates after IVF or ICSI appear to have reached a peak, with pregnancy rates per started treatment calculated at 27.1% after IVF and 24.3% after ICSI.

25 Jun 2019

Men who delay fatherhood put health of partners, unborn children at risk

Men who delay starting a family have a ticking "biological clock" -- just like women -- that may affect the health of their partners and children, according to Rutgers researchers.

13 May 2019

Exposure to particulate air pollution may lead to reduced sperm production

Exposure to tiny air pollution particles may lead to reduced sperm production, suggests new research in mice to be presented Monday, March 25 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

New research opens possibility of using sperm taken from testicles to overcome infertility

Scientists have found that sperm DNA from the testicles of many infertile men is as good as that of ejaculated sperm of fertile men. This may explain a major cause of male infertility and opens the possibility of using sperm taken directly from the testicles of these men; to overcome their infertility

15 Mar 2019

Chemicals at home responsible for decreased fertility in men and dogs

A new study has found that chemical and environmental contaminants at home and diet could be responsible for decreasing fertility of the men and the domestic pet dogs living in the house. The results of the new study were published in the latest issue of the journal Scientific Reports.

4 Mar 2019