Melanoma News and Research

Latest Melanoma News and Research

Researchers prove existence of olfactory receptor in pigment-producing skin cells

Researchers at Ruhr-Universität Bochum were the first ones to prove the existence of an olfactory receptor in pigment-producing cells in human skin, the so-called melanocytes. The team headed by Prof Dr Dr Dr habil. Hanns Hatt demonstrated that the violet-like scent Beta-Ionone can activate the receptor.

4 Jun 2016

New treatment shows promise against hard-to-treat eye cancer

Eye cancer took the life of author and neurologist Oliver Sacks last year, bringing attention to the rare and deadly disease. Scientists have tried to develop precision treatments against cancers like this one, but the mutations that cause them have proven difficult to block with drugs.

3 Jun 2016

Stimulating STING pathway to provoke life-extending immune response shows promise in AML

A protein known as STING plays a crucial role in the immune system's ability to "sense" cancer by recognizing and responding to DNA from tumor cells. Injection of compounds that activate the STING pathway directly into solid tumors in mice has been shown in prior studies to result in very potent anti-tumor immune responses.

3 Jun 2016

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Neuroblastoma tumors shrank, some dramatically, in 80 percent of newly diagnosed, young, high-risk patients enrolled in a Phase II clinical trial that included an experimental monoclonal antibody. The immunotherapy agent was produced on the St. Jude Children's Research Hospital campus where the study is still underway.

3 Jun 2016

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Cancer immunotherapies--drugs that work by making a patient's immune system better at spotting and destroying tumor cells--are increasingly generating headlines. A number of these drugs are now being used for the treatment of melanoma, lung, and kidney cancers, and are showing promise in clinical trials with other diseases as well.

3 Jun 2016

Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Small cell lung cancer (SCLC) represents approximately 14 percent of all types of lung cancer. Many patients with SCLC respond to initial chemotherapy; however, they eventually relapse and develop progressive disease that has no effective treatment options.

2 Jun 2016

Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

Today, using anatomic pathology, the differences in appearance of a normal or a malignant lesion can be difficult to tell when just using light microscopy.

2 Jun 2016

Researchers identify potential therapeutic target against oncogenic viral infection

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in immune-compromised individuals.

1 Jun 2016

Counsyl expands into oncology market to increase cancer risk screening

Counsyl, a DNA testing and genetic counseling service, today announced its expansion into the oncology market, with a focus on advancing cancer risk screening and helping cancer prevention efforts.

31 May 2016

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, "Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient," that will be published online May 30 in The Journal of Experimental Medicine.

30 May 2016

Researchers develop new drugs for melanoma

Finding new, more effective and personalised treatments for cancer is the challenge of many researchers. A challenge that has been successfully met by a team from Inserm led by Stéphane Rocchi, which has just synthesised and developed new drugs for melanoma.

28 May 2016

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors.

27 May 2016

Adolescents and young adults have lower cancer survival rates compared to children

More young people of all ages are surviving cancer than ever before, but new research published today in The Lancet Oncology journal shows that adolescents and young adults have a lower chance of surviving eight relatively common types of cancer than children, according to the latest data from a long-running study of cancer survival across Europe.

27 May 2016

Novel photonics device that listens to light can accurately detect skin cancer

Scientists are developing a new photonics device that listens to light and could be capable of detecting skin cancer and other diseases more accurately than ever before, eliminating the need for unnecessary and invasive biopsies.

27 May 2016

Advanced cancer patients lack palliative, hospice care

Medical societies, including the American Society of Clinical Oncology, recommend that patients with advanced cancer receive palliative care soon after diagnosis and receive hospice care for at least the last three days of their life. Yet major gaps persist between these recommendations and real-life practice, a new study shows.

27 May 2016

SBP scientists discover new regulator of immune responses

Research led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a new regulator of immune responses. The study, published recently in Immunity, sheds new light on why T cells fail to clear chronic infections and eliminate tumors.

26 May 2016

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.

24 May 2016

Researchers find ways to switch on Natural Killer cells to combat cancer

Our bodies are constantly and successfully fighting off the development of cells that lead to tumours - but when there is disruption to this process cancer is free to develop.

24 May 2016

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Melanoma News and Research

Latest Melanoma News and Research

Researchers prove existence of olfactory receptor in pigment-producing skin cells

New treatment shows promise against hard-to-treat eye cancer

Stimulating STING pathway to provoke life-extending immune response shows promise in AML

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

New mouse model allows researchers to evaluate CD40-antibody drugs effectively

Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

Researchers identify potential therapeutic target against oncogenic viral infection

Counsyl expands into oncology market to increase cancer risk screening

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Researchers develop new drugs for melanoma

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Adolescents and young adults have lower cancer survival rates compared to children

Novel photonics device that listens to light can accurately detect skin cancer

Advanced cancer patients lack palliative, hospice care

SBP scientists discover new regulator of immune responses

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Researchers find ways to switch on Natural Killer cells to combat cancer

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Melanoma News and Research

Latest Melanoma News and Research

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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