Melanoma News and Research

Latest Melanoma News and Research

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

Computational, cell biological, and human tissue-based studies establish GPNMB as a risk gene and potential therapeutic target for Parkinson's Disease (PD), researchers report.

18 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

16 Aug 2022

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Researchers around the world have been working for years on developing vaccines against different types of cancer, but without much success. Now, Tufts School of Engineering researchers think they have found one that does work. They have devised a method of targeting cancer in mice with a vaccine that is so strong and precise, it eliminates tumors and even prevents their recurrence.

16 Aug 2022

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat a range of cancers.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Skin cancer is a risk no matter the skin tone. But it may be overlooked in people with dark skin.

Brykyta Shelton found herself standing in a checkout line of a big-box retailer, uncomfortably aware as a woman ahead of her stared at her sandaled feet.

5 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

'RNA fishing' technique identifies several proteins involved in the progression of melanoma

Researchers at the Centre for Genomic Regulation have identified several proteins involved in the progression of melanoma, the deadliest form of skin cancer.

3 Aug 2022

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed and optimized a minimally invasive method for more targeted, efficient, and sustained delivery of immunotherapeutic treatments for cancer.

2 Aug 2022

Alliance MCED Biobank Study may provide greater understanding of how to detect multiple cancers

The Alliance for Clinical Trials in Oncology, in partnership with the National Cancer Institute, part of the National Institutes of Health, today announced the opening of a new study for participant enrollment that aims to obtain a reference set of blood samples from newly diagnosed patients with cancer and healthy individuals without cancer to include in a future study to assess the utility of early cancer detection blood tests.

1 Aug 2022

Frequent aspirin use associated with lower ovarian cancer risk in people with multiple risk factors

Frequent aspirin use is linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published in the Journal of Clinical Oncology.

26 Jul 2022

Study may help overcome some obstacles to the development of nanoparticle-based drugs

Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy.

21 Jul 2022

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

The University of Texas MD Anderson Cancer Center and Obsidian Therapeutics, Inc. today announced Food and Drug Administration (FDA) clearance of an Investigational New Drug (IND) application for an MD Anderson-sponsored Phase I clinical study of OBX-115, Obsidian's lead engineered tumor infiltrating lymphocyte (TIL) therapy candidate.

21 Jul 2022

Melanoma News and Research

Latest Melanoma News and Research

GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

Researchers visualize antigen-bound T-cell receptor at atomic resolution

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Researchers synthesize a small molecule that can be used to treat a range of cancers

Terminally exhausted T cells may remain competent for transcription, researchers say

Skin cancer is a risk no matter the skin tone. But it may be overlooked in people with dark skin.

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

'RNA fishing' technique identifies several proteins involved in the progression of melanoma

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

Alliance MCED Biobank Study may provide greater understanding of how to detect multiple cancers

Frequent aspirin use associated with lower ovarian cancer risk in people with multiple risk factors

Study may help overcome some obstacles to the development of nanoparticle-based drugs

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

International Agency for Research on Cancer classifies firefighting as carcinogenic

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

Scientists find a promising new combination therapy for certain types of lung tumors

Machine learning models help forecast immunotherapy response from gut microbiomes

Discovery about how a certain protein is activated in tumor cells could lead to better treatments

Innovation in neuroscience drug discovery - eBook eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

Melanoma News and Research

Latest Melanoma News and Research

Innovation in neuroscience drug discovery - eBook eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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