Metabolism News and Research

Latest Metabolism News and Research

Study offers clues for earlier diagnosis of folate deficiency

As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who carry certain genetic variants, dealing with folate deficiency can be a life-long struggle which can lead to serious neurological and heart problems and even death.

1 Jul 2021

The impact of COVID-19 on dialysis patients

In this interview, News-Medical speaks to Professor Simon Davies and Dr. Raymond Vanholder about the impact of COVID-19 on kidney dialysis patients.

1 Jul 2021

New study maps evolutionary history and interrelationships of protein domains

Proteins have been quietly taking over our lives since the COVID-19 pandemic began. We've been living at the whim of the virus's so-called "spike" protein, which has mutated dozens of times to create increasingly deadly variants. But the truth is, we have always been ruled by proteins. At the cellular level, they're responsible for pretty much everything.

1 Jul 2021

Study offers a new model for examining genetic risk associated with nicotine dependence

Some people casually smoke cigarettes for a while and then stop without a problem, while others develop long-term, several packs-per-day habits. A complex mix of environmental, behavioral, and genetic factors appear to raise this risk for nicotine dependence.

1 Jul 2021

Reactive oxygen species are important components in cancer treatments

Reactive oxygen species (ROS) are highly reactive chemicals which contain oxygen radicals. Hypochlorous acid, peroxides, superoxide, singlet oxygen, alpha-oxygen and hydroxyl radicals are the major examples of ROS, which are familiar to persons from many walks of life as they are used in many domestic and industrial processes.

1 Jul 2021

Discovery of blood biomarker opens new perspectives for dietary prevention of AMD-related risks

Age-related macular degeneration (AMD) is the principal cause of vision loss in industrialised countries, with nearly 20 million people affected in Europe in 2020. Although identified as a risk factor, until now it was impossible to evaluate retinal omega-3 fatty acid deficits.

30 Jun 2021

New biomarkers can predict HIV remission after antiretroviral therapy interruption

New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure.

29 Jun 2021

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

The LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies against Alzheimer's disease.

29 Jun 2021

Study investigates the link between skeletal muscle proteome and type 2 diabetes

Globally, more than 400 million people have diabetes, most of them suffering from type 2 diabetes.

29 Jun 2021

Research shines new light on deadly medulloblastoma metastases

With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, or metastasize.

29 Jun 2021

Optibrium Publishes Major Peer-Reviewed Study on AI Applications to Global Pharma Data

Optibrium Limited today announced the publication of a peer-reviewed study in Applied AI Letters, “Deep Imputation on Large-Scale Drug Discovery Data”.

From Optibrium Ltd. 29 Jun 2021

Acidic environment enhances production of butyric acid from apple pectin by fecal microbiota

Researchers from Tallinn University of Technology, Grete Raba, Signe Adamberg, and Kaarel Adamberg showed that an acidic environment enhances the production of butyric acid from apple pectin by fecal bacterial consortia - microbiota.

29 Jun 2021

Lowering iron content in fat cells prevented mice from gaining excess weight

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines, UT Southwestern scientists report in a new study. The findings, published online in Cell Metabolism, could eventually lead to new strategies to protect people against obesity and related diseases.

29 Jun 2021

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

The National Cancer Institute has awarded the Lung Cancer Metabolism Working Group at Moffitt Cancer Center with a Research Program Project Grant (P01CA250984).

28 Jun 2021

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively.

28 Jun 2021

Over-the-counter antacids may improve glucose levels in people with diabetes

Antacids improved blood sugar control in people with diabetes but had no effect on reducing the risk of diabetes in the general population, according to a new meta-analysis published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

25 Jun 2021

New book reveals promising nanomaterials for therapeutic drug delivery

'Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery' gives the present status and future perspective of Polymeric nanoparticles, Liposomes, Carbon Nanotubes, Magnetic Nanoparticles, Silica Based nanomaterial, Hydrogels, Metallic Nanoparticles, Cyclodextrins, Poly (Lactide-Co-Glycolide) and its Copolymers.

25 Jun 2021

Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis

In a new study published in Circulation Research, Chen-Yu Zhang and Xiaohong Jiang's group from Nanjing University and Dongjin Wang's group from Nanjing Drum Tower Hospital reported a critical role of PGC1α in maintaining the contractile phenotype of vascular smooth muscle cells (VSMCs) and highlighted the therapeutic potential of PGC1α for atherosclerosis.

25 Jun 2021

Researchers trace gecko’s skin tumors to a gene implicated in deadly cancer

The leopard gecko's name was Mr. Frosty, and he was hard to miss. Yellow bands striped his back, and uncommonly white skin peeked out from speckles on his head and tail.

25 Jun 2021

City of Hope researchers identify how breast cancer cells acquire resistant traits

City of Hope, a world-renowned cancer research and treatment center, has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies, according to a new study published in Nature Cancer.

24 Jun 2021

Metabolism News and Research

Latest Metabolism News and Research

Study offers clues for earlier diagnosis of folate deficiency

The impact of COVID-19 on dialysis patients

New study maps evolutionary history and interrelationships of protein domains

Study offers a new model for examining genetic risk associated with nicotine dependence

Reactive oxygen species are important components in cancer treatments

Discovery of blood biomarker opens new perspectives for dietary prevention of AMD-related risks

New biomarkers can predict HIV remission after antiretroviral therapy interruption

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

Study investigates the link between skeletal muscle proteome and type 2 diabetes

Research shines new light on deadly medulloblastoma metastases

Optibrium Publishes Major Peer-Reviewed Study on AI Applications to Global Pharma Data

Acidic environment enhances production of butyric acid from apple pectin by fecal microbiota

Lowering iron content in fat cells prevented mice from gaining excess weight

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Over-the-counter antacids may improve glucose levels in people with diabetes

New book reveals promising nanomaterials for therapeutic drug delivery

Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis

Researchers trace gecko’s skin tumors to a gene implicated in deadly cancer

City of Hope researchers identify how breast cancer cells acquire resistant traits

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production