Metabolism News and Research

Latest Metabolism News and Research

Blocking ABCB10 protein in liver cells protects against high blood sugar, fatty liver disease

A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice.

20 May 2021

New pan-European survey explores the effect of COVID-19 restrictions on physical, mental health

A new pan-European survey funded by the Institute for Scientific Information on Coffee exploring the impact of COVID-19 Lockdowns and associated restrictions (in those countries where there has been no Lockdown), has found that nearly two thirds of adults (61%) expressed concern about their worsening mood; two times higher than those concerned about physical inactivity (24%).

20 May 2021

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.

18 May 2021

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19.

18 May 2021

Researchers report promising biotherapeutics for obesity and related medical complications

The research teams at the University of Hong Kong led by Professor Xuechen LI from the Research Division for Chemistry and Department of Chemistry, and Professor Yu WANG from the Department of Pharmacology and Pharmacy, reported a synthetic biotherapeutics with promising anti-tumor, insulin sensitising and hepatoprotective activities in the Journal of the American Chemical Society.

18 May 2021

A potential treatment to prevent obesity-related liver damage

One of the especially dangerous health risks of being extremely overweight occurs when an obese person begins to accumulate fat in their liver.

18 May 2021

New framework could help manage COVID-19, deal with other major stresses

A new analysis of the effects of SARS-CoV-2, the virus causing the current pandemic, on the human body has provided novel insights into the nature of resilience and how we deal with stressful situations.

17 May 2021

New way to detect a diverse range of bacteria that cause diarrheal disease in informal settlements

Monash University researchers have validated a way to successfully detect a diverse range of bacteria (pathogens) that cause diarrheal disease in informal settlements.

17 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

UCL scientists identify new immunotherapy to combat hepatitis B virus

Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world.

14 May 2021

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

Do labels on commercial kefir products report microbial levels correctly?

A recent study in the journal JDS Communications reports the results of an analysis of five brands of kefir on the US market, indicating the need for stricter regulation of this field.

14 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

New study may help develop senolytic drugs that target senescent immune cells

In a study recently published in Nature University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

13 May 2021

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Mycobacterium tuberculosis is incredible in that it can survive for decades within its human host. It does this by varying its diet to successfully steal nutrients from the human host including immune cells; it is known to acquire and absorb multiple carbon sources from the body during infection.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

The first global review of complementary medicines (herbal and dietary supplements) for weight loss in 16 years--combining 121 randomized placebo-controlled trials including nearly 10,000 adults--suggests that their use cannot be justified based on the current evidence.

8 May 2021

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.

7 May 2021

Metabolism News and Research

Latest Metabolism News and Research

Blocking ABCB10 protein in liver cells protects against high blood sugar, fatty liver disease

New pan-European survey explores the effect of COVID-19 restrictions on physical, mental health

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

Researchers report promising biotherapeutics for obesity and related medical complications

A potential treatment to prevent obesity-related liver damage

New framework could help manage COVID-19, deal with other major stresses

New way to detect a diverse range of bacteria that cause diarrheal disease in informal settlements

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

UCL scientists identify new immunotherapy to combat hepatitis B virus

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Do labels on commercial kefir products report microbial levels correctly?

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

New study may help develop senolytic drugs that target senescent immune cells

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Sepsis can cause alterations in the functioning of defense cells that lead to death

Natural products a rich source for novel antiviral compounds

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production