Metabolism News and Research

Latest Metabolism News and Research

Himalayan marmot genome offers clues to high-altitude adaptation

Himalayan marmots can survive at altitudes up to 5,000 meters in the Himalayan regions of India, Nepal, and Pakistan and on the Qinghai-Tibetan Plateau of China, where many of them face extreme cold, little oxygen, and few other resources.

27 Dec 2018

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms.

27 Dec 2018

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Galanin-like peptide is a short peptide made up of 60 amino acid residues. This sequence is homologous across several species. The hypothalamic arcuate nucleus is the place where GALP is produced. GALP has diverse physiological effects such as the regulation of feeding, energy metabolism, and reproductive behavior.

25 Dec 2018

The impact of maternal diabetes on fetal heart development

Congenital heart disease is the most common birth defect. And even with remarkable advances in care, it remains the leading cause of non-infectious death in infants.

24 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

Simple protocol rescues stressed liver cells

Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte quality and enables cells from a wider quality spectrum to be used in standard and advanced cell culture. The findings are published in Archives of Toxicology.

21 Dec 2018

New approach to destroy HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus - it is their metabolic (or energy-producing) activity1 that enables the virus to multiply.

21 Dec 2018

New research examines cancer metabolism at multiple scales

No matter what form cancer takes in the body, it starts at the cellular level and grows via metabolism run amok.

21 Dec 2018

Experts in Parkinson's research propose roadmap for drug trials targeting alpha-synuclein

A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the progression of Parkinson's disease

20 Dec 2018

Experimental gene therapy extends lifespan of mice suffering from untreatable mitochondrial disease

Researchers at the University of Helsinki and Folkhälsan Research Center have, together with their collaborators, for the first time demonstrated in a mouse model that partial restoration of respiratory chain function in mitochondria, which serve as cellular power plants, may be sufficient to entirely prevent symptoms of a severe mitochondrial disorder.

20 Dec 2018

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

Novel ferrocenyl phosphines developed as potent antimalarial drugs

A team of researchers from the Singapore University of Technology and Design and Nanyang Technological University have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death.

20 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Mindfulness training could be excellent strategy to prevent and manage obesity

Mindfulness training may improve the effectiveness of intensive weight management programs, suggesting that it could be an excellent strategy for healthcare providers in preventing and managing obesity.

18 Dec 2018

'Little Foot' endocast reveals a small brain combining ape-like and human-like features

First ever endocast reconstruction of the nearly complete brain of the hominin known as Little Foot reveals a small brain combining ape-like and human-like features.

18 Dec 2018

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual death. Their ultimate goal is to create medications capable of stopping ALS in its tracks.

18 Dec 2018

Metabolism News and Research

Latest Metabolism News and Research

Himalayan marmot genome offers clues to high-altitude adaptation

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

NIPER researcher presents a review on autophagy in neuronal cells

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

The impact of maternal diabetes on fetal heart development

Statins reduce the formation of brown adipose tissue

Simple protocol rescues stressed liver cells

New approach to destroy HIV reservoirs

New research examines cancer metabolism at multiple scales

Experts in Parkinson's research propose roadmap for drug trials targeting alpha-synuclein

Experimental gene therapy extends lifespan of mice suffering from untreatable mitochondrial disease

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

Novel ferrocenyl phosphines developed as potent antimalarial drugs

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Mindfulness training could be excellent strategy to prevent and manage obesity

'Little Foot' endocast reveals a small brain combining ape-like and human-like features

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Research suggests a promising therapeutic target to treat or prevent metabolic disorders

Rice University scientists develop synthetic protein switches to control electron flow

New $1.6 million NIH grant supports study on a gene vital to circadian rhythms

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production