Metabolism News and Research

Latest Metabolism News and Research

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Integrating PGx testing for personalized prostate cancer treatment

Prostate cancer (PC) is a significant health concern, being the second leading cause of death among American men.

31 May 2024

Mediterranean diet linked to lower mortality risk in women

Investigators from Brigham and Women's Hospital identified and assessed underlying mechanisms that may explain the Mediterranean diet's 23 percent reduction in all-cause mortality risk for American women.

31 May 2024

Good communication between fathers and adolescents influences physical activity levels

A doctoral dissertation from the University of Jyväskylä, Finland, found that having difficulties in talking with one's father predicted a decrease in physical activity and the maintenance of low physical activity between adolescence and young adulthood.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

In contemporary society, obesity has emerged as a worldwide chronic metabolic disorder, imposing substantial burdens on both individual health and healthcare systems.

29 May 2024

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

The effects of polystyrene microplastics on pregnancy outcomes and glucose metabolism.

29 May 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

Metabolic cell death pathways could be novel therapeutic targets in cancer treatment

The review discusses how metabolic cell death, distinct from traditional forms of regulated cell death like apoptosis, arises from imbalances in cellular metabolism due to nutrient and metal overload or depletion.

28 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in cancer, diabetes and many cellular activities.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Simple vaginal swab could help detect early-stage gynecological cancers

A simple vaginal swab could reveal the presence of early-stage gynecological cancers, according to a new, wide-ranging study published in De Gruyter's Open Life Sciences.

28 May 2024

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.

28 May 2024

Genetic screening and counseling slash young adults' excessive drinking, new study reveals

A recent randomized controlled trial found that short-term interventions combining enzyme substances and behavioral changes significantly reduced excessive alcohol intake among young adults.

28 May 2024

Low vitamin D levels linked to higher diabetes risk in older adults, study finds

A meta-analysis found that low serum vitamin D levels significantly increase the risk of developing type 2 diabetes in older adults, even after adjusting for several confounders.

27 May 2024

Metabolism News and Research

Latest Metabolism News and Research

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Integrating PGx testing for personalized prostate cancer treatment

Mediterranean diet linked to lower mortality risk in women

Good communication between fathers and adolescents influences physical activity levels

Researchers uncover two classes of genetic causes for pediatric chordoma

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

Microplastics: Invisible to the eye but severely harmful to pregnancy and metabolic outcomes

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Metabolic cell death pathways could be novel therapeutic targets in cancer treatment

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

Study highlights a dietary strategy for health improvement and weight management

Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Simple vaginal swab could help detect early-stage gynecological cancers

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

Genetic screening and counseling slash young adults' excessive drinking, new study reveals

Low vitamin D levels linked to higher diabetes risk in older adults, study finds

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production