Metabolism News and Research

Latest Metabolism News and Research

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

For several decades, scientists have recognized the key role that a molecule known as GTP, one of the building blocks of RNA, plays in the development of cancer and other diseases.

13 Sep 2017

Scientists uncover how gut bacteria and body clock work together to promote fat accumulation

UT Southwestern researchers have uncovered new clues about how gut bacteria and the body's circadian clock work together to promote body fat accumulation.

12 Sep 2017

Study findings may have critical implications to boost efficacy of T cell-based therapies

T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy.

11 Sep 2017

Generation Genome: the UK’s genetics revolution?

The report set out the NHS’ intentions of routinizing whole genome sequencing. It is particularly focused towards rare diseases and cancers, although conditions such as obesity, bacterial and other infections are also included.

11 Sep 2017

Regulatory T-cells can support fat depots in dealing with environmental challenges

Immunosuppressive regulatory T-cells play an important role in the functioning of adipose tissue. This is the discovery of scientists from the Helmholtz Diabetes Center at Helmholtz Zentrum München and the Technical University of Munich.

11 Sep 2017

Penn researcher wins National Cancer Institute Outstanding Investigator Award

M. Celeste Simon, PhD, who studies cancer cell metabolism, tumor immunology, and the influence of oxygen availability and deprivation on tumor growth, has been given a National Cancer Institute Outstanding Investigator Award.

8 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Study provides first structural glimpse of circadian clock's molecular machinery

Scientists have long known that circadian clocks- biochemical oscillators that control physiology, metabolism and behavior on a roughly 24-hour cycle- are present in all forms of life, including animals, plants, fungi and some types of bacteria. However, the molecular mechanisms that "run" these systems remain largely unknown.

7 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Conducting plastics in smartphone screens can be used to trick pathogenic bacteria

Conducting plastics found in smartphone screens can be used to trick the metabolism of pathogenic bacteria, report scientists at the Swedish Medical Nanoscience Center at Karolinska Institutet in the scientific journal npj Biofilms and Microbiomes.

7 Sep 2017

New device detects cancerous tissue during surgery within seconds

Researchers from the University of Texas at Austin have invented a pen-like, handheld device that can identify cancerous tissue in around 10 seconds during surgery, offering hope that procedures to remove cancer could be made quicker, more precise and safer.

7 Sep 2017

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Porphyrias, a group of eight known blood disorders, affect the body's molecular machinery for making heme, which is a component of the oxygen-transporting protein, hemoglobin. When heme binds with iron, it gives blood its hallmark red color.

7 Sep 2017

Study sheds light on virulence strategy of intracellular bacteria that cause legionellosis

Intracellular pathogens adopt various strategies to circumvent the defences of the host cell and to proliferate intracellularly. One specific strategy is to target host organelles like the mitochondria. Mitochondria are well-defined cytoplasmic organelles, which take part in a variety of cellular metabolic functions.

7 Sep 2017

Yoganatomy helps medical students to connect, recharge and remember

Take a deep breath in. As you breathe out, answer: what did your internal intercostal muscles do when you took that breath? This isn't a common question in most yoga classes, but it is part of Yoganatomy at the Perelman School of Medicine, a yoga class that combines traditional yoga practice with reinforcement of lessons in gross anatomy.

6 Sep 2017

Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

A surprising discovery that immune cells possess an internal warehouse of glycogen used to activate immune responses could help to increase immune activity in vaccines or suppress immune reactions in autoimmune disease or hyper-inflammatory conditions.

6 Sep 2017

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

A pair of new studies find that diets termed ketogenic that are classically low in carbohydrates can prolong life in adult male laboratory mice. In addition this ketogenic diet also preserves the memory functions as well as muscle masses of the aged mice that were fed on it. The mechanism behind this could be the fact that ketogenic diet induces protein acetylation in the mice liver and muscles.

5 Sep 2017

Metabolism News and Research

Latest Metabolism News and Research

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

Scientists uncover how gut bacteria and body clock work together to promote fat accumulation

Study findings may have critical implications to boost efficacy of T cell-based therapies

Generation Genome: the UK’s genetics revolution?

Regulatory T-cells can support fat depots in dealing with environmental challenges

Penn researcher wins National Cancer Institute Outstanding Investigator Award

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Study provides first structural glimpse of circadian clock's molecular machinery

Seeing the full picture, real-time analysis of live-cells

Conducting plastics in smartphone screens can be used to trick pathogenic bacteria

New device detects cancerous tissue during surgery within seconds

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Study sheds light on virulence strategy of intracellular bacteria that cause legionellosis

Yoganatomy helps medical students to connect, recharge and remember

Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

Active component rich in sugarcane may ameliorate stress, help having sound sleep

CSHLP publishes new book on The Biology of Exercise

Researchers identify impact of climatic factors on dengue disease burden in India

Fat may influence cancer development in diverse ways

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS